Fermentative Production of Guanosine by 8-Azaguanine Resistant ofBacillus subtilis

Production of Guanosine by Psicofuranine and Decoyinine Resistant Mutants ofBacillus subtilis

“…[1][2][3][4][5] We have also already reported that we derived methionine sulfoxide resistant mutants from an inosineproducing strain of Bacillus subtilis, and obtained a mutant AG 169 that did not excrete inosine but produced considerable amounts of xanthosine and guanosine. 6 ) But this mutant could not accumulate a sufficient amount of guanosine to be contented.…”

Genetic and Biochemical Studies on 5′-Nucleotide Fermentation

“…There was no difference in the effect of guanosine on the total amount of purine nucleosides produced, including both xanthosine and inosine, in these two strains. papers (1)(2)(3)(4)(5)(6)(7)(8)(9), there is as yet very little information concerning the mechanism by which each of these products is accumulated. However, for the industrial production of large amounts of individual purine nucleosides, it is important to know what kinds of genetic traits determine the pattern of accumulation.…”