Femtosecond laser ablation particle introduction to a liquid sampling-atmospheric pressure glow discharge ionization source

Carado, Anthony J.; Quarles, C. Derrick; Duffin, Andrew M.; Barinaga, Charles J.; Russo, Richard E.; Marcus, R. Kenneth; Eiden, Gregory C.; Koppenaal, David W.

doi:10.1039/c2ja10331a

Cited by 29 publications

(25 citation statements)

References 22 publications

(24 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The coupling of the liquid sampling-atmospheric pressure glow discharge (LS-APGD) microplasma and the Exactive Orbitrap has been previously presented with respect to multi-element analysis of aqueous solutions and laser ablation-produced particulates [16,17,21]. The ultimate goal in this task's work on the LS-APGD technique is to provide an ionization source that facilitates portable or field-deployable mass spectrometry.…”

Section: Discussionmentioning

confidence: 99%

“…In the case of the APCI, the predominate ionization mechanism is a proton transfer reaction, whereas ionization of atomic species in the ICP or LS-APGD plasmas is via electron ionization. Furthermore, the LS-APGD has also been used as a secondary ion source for laser ablation samples and as a desorption ionization source for organic samples [21,22]. The work presented here seeks to demonstrate that a LS-APGD microplasma source is a viable option for isotope ratio mass spectrometry (IRMS).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Preliminary Figures of Merit for Isotope Ratio Measurements: The Liquid Sampling-Atmospheric Pressure Glow Discharge Microplasma Ionization Source Coupled to an Orbitrap Mass Analyzer

Hoegg

Barinaga

Hager

et al. 2016

J. Am. Soc. Mass Spectrom.

Self Cite

View full text Add to dashboard Cite

Abstract. In order to meet a growing need for fieldable mass spectrometer systems for precise elemental and isotopic analyses, the liquid sampling-atmospheric pressure glow discharge (LS-APGD) has a number of very promising characteristics. One key set of attributes that await validation deals with the performance characteristics relative to isotope ratio precision and accuracy. Owing to its availability and prior experience with this research team, the initial evaluation of isotope ratio (IR) performance was performed on a Thermo Scientific Exactive Orbitrap instrument. While the mass accuracy and resolution performance for Orbitrap analyzers are well-documented, no detailed evaluations of the IR performance have been published. Efforts described here involve two variables: the inherent IR precision and accuracy delivered by the LS-APGD microplasma and the inherent IR measurement qualities of Orbitrap analyzers. Important to the IR performance, the various operating parameters of the Orbitrap sampling interface, high-energy collisional dissociation (HCD) stage, and ion injection/data acquisition have been evaluated. The IR performance for a range of other elements, including natural, depleted, and enriched uranium isotopes was determined. In all cases, the precision and accuracy are degraded when measuring low abundance (<0.1% isotope fractions). In the best case, IR precision on the order of 0.1% RSD can be achieved, with values of 1%-3% RSD observed for low-abundance species. The results suggest that the LS-APGD is a promising candidate for field deployable MS analysis and that the high resolving powers of the Orbitrap may be complemented with a here-to-fore unknown capacity to deliver high-precision IRs.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Preliminary Figures of Merit for Isotope Ratio Measurements: The Liquid Sampling-Atmospheric Pressure Glow Discharge Microplasma Ionization Source Coupled to an Orbitrap Mass Analyzer

Hoegg

Barinaga

Hager

et al. 2016

J. Am. Soc. Mass Spectrom.

Self Cite

View full text Add to dashboard Cite

show abstract

“…The ability to perform accurate and precise isotope ratio measurements of uranium (U) is of critical value, in the field of nonproliferation, where U enrichment is a cornerstone towards the development of nuclear programs. Monitoring nuclear material in facilities can be facilitated by field deployable mass spectrometers . Currently, the field of isotope ratio analysis relies heavily on multi‐collector inductively coupled plasma mass spectrometry (MC‐ICP‐MS; the workhorse of the nuclear material isotopic analyses) and thermal ionization mass spectrometry (TIMS; considered the “gold standard”) .…”

Section: Introductionmentioning

confidence: 99%

Determination of uranium isotope ratios using a liquid sampling atmospheric pressure glow discharge/Orbitrap mass spectrometer system

Hoegg

Marcus

Koppenaal

et al. 2017

Rapid Comm Mass Spectrometry

Self Cite

View full text Add to dashboard Cite

The LS-APGD/Orbitrap system, while still in the preliminary stages of development, offers highly accurate and precise isotope ratio results that suggest a potential paradigm shift in the world of isotope ratio analysis. Furthermore, the portability of the LS-APGD as an elemental ion source, combined with the small size and smaller operating demands of the Orbitrap, suggests that the instrumentation is capable of being field-deployable.

show abstract

“…The LS-APGD also is effective for OES and MS analysis of laser-ablated particles [34][35][36] and direct surface probing for ambient desorption ionization mass spectrometry (ADI-MS) [33]. A parametric evaluation of the LA-LS-APGD-OES implementation was performed with respect to discharge current, gas flow rate, and electrode gap [35], and their effects on rotational temperatures, excitation temperatures, and electron number densities.…”

Section: Introductionmentioning

confidence: 99%

Investigation of spectrochemical matrix effects in the liquid sampling-atmospheric pressure glow discharge source

Manard

González

Sarkar

et al. 2014

Spectrochimica Acta Part B: Atomic Spectroscopy

Self Cite

View full text Add to dashboard Cite

The liquid sampling-atmospheric pressure glow discharge (LS-APGD) microplasma was evaluated with regards to its spectrochemical robustness in its application as a miniaturized optical emission spectroscopy (OES) source for liquid samples. The susceptibility to perturbations in excitation/ionization conditions was probed across a wide range test species, including transition metals, easily ionized elements (group I), and elements with low second ionization potentials (group II). Spectrochemical metrics included the plasma excitation temperature (T exc), ionization temperatures (T ion), and magnesium (Mg) ionic:atomic (Mg II:Mg I) ratios. The introduction of the 11 different matrix elements into the LS-APGD at concentrations of 500 g mL-1 yielded no significant changes in the optically-determined plasma characteristics, indicating a relative immunity to spectrochemical matrix effects. T exe values for the plasma, using He I as the spectrometric species averaged 2769 ± 79 K across the test matrix, with Mg-based ionization temperature values centered at 6665 ± 151 K. Typical Mg II:Mg I ratios (the so-called robustness parameter) were 0.95 ± 0.3. The lack of appreciable perturbation in excitation/ionization conditions observed here is also manifested in virtually no changes in the probe Mg II and I species' intensities, even at matrix loadings of up 1000 g mL-1 of Ba. These observations indicate that the LS-APGD could serve as an OES source for the analysis of diverse aqueous samples without appreciable spectroscopic matrix effects, though potential physical matrix effects including vaporization effects must be evaluated.

show abstract

Femtosecond laser ablation particle introduction to a liquid sampling-atmospheric pressure glow discharge ionization source

Cited by 29 publications

References 22 publications

Preliminary Figures of Merit for Isotope Ratio Measurements: The Liquid Sampling-Atmospheric Pressure Glow Discharge Microplasma Ionization Source Coupled to an Orbitrap Mass Analyzer

Preliminary Figures of Merit for Isotope Ratio Measurements: The Liquid Sampling-Atmospheric Pressure Glow Discharge Microplasma Ionization Source Coupled to an Orbitrap Mass Analyzer

Determination of uranium isotope ratios using a liquid sampling atmospheric pressure glow discharge/Orbitrap mass spectrometer system

Investigation of spectrochemical matrix effects in the liquid sampling-atmospheric pressure glow discharge source

Contact Info

Product

Resources

About