Female attempted suicide patients with low HDL levels are at higher risk of suicide re-attempt within the subsequent year: A clinical cohort study

Emet, Mücahit; Yücel, Atakan; Özcan, Halil; Gür, Sultan Tuna Akgöl; Sarıtemur, Murat; Bulut, Nevzat; Gümüşdere, Musa

doi:10.1016/j.psychres.2014.11.026

Cited by 14 publications

(4 citation statements)

References 44 publications

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“…A previous study on female patients found lower cholesterol levels in women with violent suicide attempts compared to women with nonviolent suicide-attempts and controls (Vevera et al, 2003). Other studies have found associations between low HDL and suicide attempts in women (Emet et al, 2015;Zhang et al, 2005). Our study did not include suicidal behaviour as an outcome.…”

Section: Clinical and Ethical Implicationsmentioning

confidence: 81%

Low cholesterol level as a risk marker of inpatient and post-discharge violence in acute psychiatry – A prospective study with a focus on gender differences

Eriksen

Bjørkly

Lockertsen

et al. 2017

Psychiatry Research

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Several studies indicate an association between low levels of serum cholesterol and aggressive behaviour, but prospective studies are scarce. In this naturalistic prospective inpatient and post-discharge study from an acute psychiatric ward, we investigated total cholesterol (TC) and high-density lipoprotein (HDL) as risk markers of violence. From March 21, 2012, to March 20, 2013, 158 men and 204 women were included. TC and HDL were measured at admission. Violence was recorded during hospital stay and for the first 3 months post-discharge. Univariate and multivariate binary logistic regression were used to estimate associations between low TC and low HDL and violence. Results showed that HDL level was significantly inversely associated with violence during hospital stay for all patients. For men, but not for women, HDL level was significantly inversely associated with violence the first 3 months post-discharge. Results indicate that low HDL is a risk marker for inpatient and post-discharge violence in acute psychiatry and also suggest gender differences in HDL as a risk marker for violence.

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Section: Clinical and Ethical Implicationsmentioning

confidence: 81%

Low cholesterol level as a risk marker of inpatient and post-discharge violence in acute psychiatry – A prospective study with a focus on gender differences

Eriksen

Bjørkly

Lockertsen

et al. 2017

Psychiatry Research

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“…Specifically, there is a pressing need to identify factors that differentiate suicide attempts in females from those in males. From previous studies, it is currently understood that females are at greater risk for attempted suicide worldwide (Emet et al, 2015; Jeon et al, 2013; Plattner et al, 2007), but males utilize violent methods more frequently in Western countries (Lucas et al, 2014) which may account for their higher rate of suicide death compared to females. Other studies have also noted gender differences in socio-demographic and psychiatric factors (Chau et al, 2014; Tsirigotis et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Gender differences among medically serious suicide attempters aged 15–54 years in rural China

Sun

Zhang

2017

Psychiatry Research

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China is one of few countries which reported higher female suicide rates in the worldwide. However, little is known about the gender differences among Chinese rural suicide attempters. This study aims to analyze the gender differences among medically serious suicide attempters aged 15–54 years in rural China. Subjects were 791 medically serious suicide attempters and 791 controls aged 15–54 years in rural China. Socio-demographic, psychological and some critical variables were assessed in the interview. The results showed that all of the factors (education years, family suicide history, negative life events, social support, impulsivity and mental disorder) associated with male suicide attempters also could be found for females. Physical disease, mental disorder and pesticide ingestion played more roles on male suicide attempters. Ever married, peasant, religious belief, and less social support played more roles on female suicide attempters. Compared with male suicide attempters, female ones are mainly influenced by social factors. A gender-specific approach should be emphasized in suicide prevention.

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“…For example, Raikkonen, Matthews, and Kuller (2002) reported reciprocal associations between psychological states and metabolic syndrome (characterized by high total cholesterol, triglycerides, and other cardiovascular markers) in adults and found, in part, that metabolic syndrome at baseline predicted increasing levels of anger and anxiety over time. In addition, among psychiatric inpatients, low HDL or high total cholesterol and triglycerides have been found to predict violence and aggressive behavior, self-injury, and risk for repeated suicide attempts (Emet et al, 2015; Eriksen, Bjørkly, Lockertsen Færden, & Roaldset, 2017; Roaldset, Bakken, & Bjørkly, 2011). Finally, in a community sample of over 400,000 individuals, low HDL predicted the onset of mood disorders over a 2-year period (Kim, Han, Jang, & Park, 2018).…”

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confidence: 99%

Lipid Profiles at Birth Predict Teacher-Rated Child Emotional and Social Development 5 Years Later

Manczak

Gotlib²

2019

Psychol Sci

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The fetal environment has been increasingly implicated in later psychological health, but the role of lipids is unknown. Drawing on the ethnically diverse Born in Bradford (BiB) birth cohort, the current study related levels of high-density lipoprotein (HDL), very-low-density lipoprotein (VLDL), and triglycerides in umbilical cord blood to 1,369 children’s teacher-rated psychosocial competence approximately 5 years later. Results of ordinal logistic regressions indicated that low levels of HDL, high levels of VLDL, and high levels of triglycerides predicted greater likelihood of being rated as less competent in domains of emotion regulation, self-awareness, and interpersonal functioning. Furthermore, these results generalized across ethnic background and children’s sex and were not accounted for by variables reflecting mothers’ psychological or physical health, children’s physical health, or children’s special education status. Together, these results identify fetal exposure to anomalous lipid levels as a possible contributor to subsequent psychological health and social functioning.

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Female attempted suicide patients with low HDL levels are at higher risk of suicide re-attempt within the subsequent year: A clinical cohort study

Cited by 14 publications

References 44 publications

Low cholesterol level as a risk marker of inpatient and post-discharge violence in acute psychiatry – A prospective study with a focus on gender differences

Low cholesterol level as a risk marker of inpatient and post-discharge violence in acute psychiatry – A prospective study with a focus on gender differences

Gender differences among medically serious suicide attempters aged 15–54 years in rural China

Lipid Profiles at Birth Predict Teacher-Rated Child Emotional and Social Development 5 Years Later

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