Fellow-eye comparison of posterior capsule opacification rates after implantation of 1CU accommodating and AcrySof MA30 monofocal intraocular lenses

Hancox, Joanne; Spalton, David J.; Heatley, Catherine J.; Jayaram, Hari; Yip, Jennifer; Boyce, J.F.; Marshall, John

doi:10.1016/j.jcrs.2006.10.056

Cited by 25 publications

(22 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The duration of follow-up ranged from 4 weeks to 3 years, with most being at least 1 year. Attrition was significantly high (O30%) in 3 16,20,23 of the 7 studies that reported dropout rates. Only 3 trials reported using more than 1 blinding method (examiner-and patient-masked).…”

Section: Description Of Studiesmentioning

confidence: 97%

See 1 more Smart Citation

Functional assessment of accommodating intraocular lenses versus monofocal intraocular lenses in cataract surgery: Metaanalysis

Takakura¹,

Iyer²,

Adams³

et al. 2010

Journal of Cataract and Refractive Surgery

View full text Add to dashboard Cite

show abstract

Section: Description Of Studiesmentioning

confidence: 97%

“…Four of the 5 studies that mentioned PCO 14,16,19,23,24 reported increased rates in the accommodating IOL group several months postoperatively (Table 4). Of note, 1 study 17 reported anterior chamber hemorrhage and another, 15 posterior capsule shrinkage.…”

Section: Adverse Effectsmentioning

confidence: 99%

Functional assessment of accommodating intraocular lenses versus monofocal intraocular lenses in cataract surgery: Metaanalysis

Takakura¹,

Iyer²,

Adams³

et al. 2010

Journal of Cataract and Refractive Surgery

View full text Add to dashboard Cite

show abstract

“…Despite the general interest in accommodative IOLs, the aberrant proliferation of lens epithelial cells and the resultant increase in light-scattering modifications and capsule fibrosis may become limiting factors. 12 The new focusable IOL technology will reduce the association of the IOL with the lens capsule because of the dynamic nature of this technology; consequently, the barrier effect will be minimized.…”

mentioning

confidence: 99%

A Fully Human In Vitro Capsular Bag Model to Permit Intraocular Lens Evaluation

Dawes

Illingworth

Wormstone

2012

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

PURPOSE.To establish a fully human in vitro culture model with which to test the putative effects of intraocular lens (IOL) designs in preventing posterior capsule opacification (PCO) after cataract surgery. METHODS. A sham cataract operation was performed to prepare human capsular bags from donor lenses. In one capsular bag of a donor pair, an intraocular lens (PMMA round-edge IOL or acrylic IOL) was implanted while the other capsular bag remained aphakic. Bags were transferred to a Petri dish and secured anterior-face down using entomological pins. Capsular bags were maintained in Eagle's minimum essential medium supplemented with 2% human serum and 10 ng/mL TGF-␤ to drive growth and matrix contraction. RESULTS. In the absence of an IOL, cells appeared within the central posterior capsule at 4.38 Ϯ 0.26 days, whereas in the presence of a PMMA round-edge IOL or an acrylic IOL they appeared at 8 Ϯ 0.41 days and 11 Ϯ 0.7 days, respectively. Immunocytochemical analysis showed an accumulation of cells at the edge of the acrylic IOL and a less evident accumulation with the PMMA round-edge IOL. Moreover, matrix contraction was more prominent in the absence of an IOL but was still apparent, to a lesser degree, in the presence of a PMMA round-edge IOL. The acrylic IOL greatly suppressed matrix contraction. CONCLUSIONS. The authors have developed a fully human in vitro capsular bag system that relates well to clinical observations and permits the testing of novel intraocular lenses. (Invest Ophthalmol Vis Sci. 2012;53:23-29)

show abstract

“…PCO-induced decrease of VA can be treated by opening the posterior lens capsule by a Nd:YAG capsulotomy 28 . After the capsulotomy, computer PCO assessment is no longer possible and these dropouts can considerably bias study results 29,30 . Buehl and associates 7 published an article in which they identified the difficult statistical problems caused by missing data attributable to Nd:YAG laser capsulotomies in long-term PCO trials, especially when a study includes many capsulotomies.…”

Section: Discussionmentioning

confidence: 99%

Long-term follow-up of posterior capsule opacification after AquaLase and NeoSoniX phacoemulsification

Stepanov¹,

Nekolová²,

Jirásková³

et al. 2016

BIOMED PAP

View full text Add to dashboard Cite

Aim.To compare the degree of posterior capsule opacification (PCO) after AquaLase and NeoSoniX phacoemulsification methods during an 8-year follow-up period using two types of software. Design. Prospective, randomized clinical trial. Methods. AquaLase was used in the right eye and NeoSoniX in the left eye of each patient with bilateral cataract. Results. Fifty patients were analyzed 1 year, 46 patients 3 years, and 37 patients 8 years after cataract surgery. Mean EPCO 2000 values were for the AquaLase group 0.324 ± 0.305 and for the NeoSoniX group 0.298 ± 0.341 (P = 0.53) 1 year after surgery, for the AquaLase group 0.582 ± 0.506 and for the NeoSoniX group 0.594 ± 0.515 (P = 0.87) 3 years after surgery, and for the AquaLase group 0.648 ± 0.567 and for the NeoSoniX group 0.673 ± 0.542 (P = 0.30) 8 years after surgery. The OSCA results were for the AquaLase group 0.7097 ± 0.3778 and for the NeoSoniX group 0.8584 ± 0.4323 (P = 0.046) 1 year after surgery, for the AquaLase group 0.9667 ± 0.736 and for the NeoSoniX group 0.9540 ± 0.5250 (P = 0.91) 3 years after surgery, and for the AquaLase group 1,035 ± 0,952 and for the NeoSoniX group 1,103 ± 0,741 (P = 0.44) 8 years after surgery. Conclusion. There was minimal PCO difference between these 2 approaches, AquaLase and NeoSoniX. Neither AquaLase nor NeoSoniX technique was able to prevent a natural progression of PCO.

show abstract

Fellow-eye comparison of posterior capsule opacification rates after implantation of 1CU accommodating and AcrySof MA30 monofocal intraocular lenses

Cited by 25 publications

References 24 publications

Functional assessment of accommodating intraocular lenses versus monofocal intraocular lenses in cataract surgery: Metaanalysis

Functional assessment of accommodating intraocular lenses versus monofocal intraocular lenses in cataract surgery: Metaanalysis

A Fully Human In Vitro Capsular Bag Model to Permit Intraocular Lens Evaluation

Long-term follow-up of posterior capsule opacification after AquaLase and NeoSoniX phacoemulsification

Contact Info

Product

Resources

About