Feline herpes dermatitis treated with interferon omega

Gutzwiller, Meret E. Ricklin; Brachelente, Chiara; Taglinger, K; Suter, Maja M.; Weissenböck, Herbert; Roosje, Petra

doi:10.1111/j.1365-3164.2007.00556.x

Cited by 24 publications

(9 citation statements)

References 25 publications

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“…Cytokines like interferons possess antiviral and anti-oncogenic properties and can therefore be used to treat certain cancers and viral infections. In cats, interferons have been administered for the treatment of feline infectious peritonitis (FIP) (Ritz et al, 2007), feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV) (de Mari et al, 2004) and feline herpes virus (FHV1) infections (Stiles, 2000;Haid et al, 2007;Gutzwiller et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of orally administered valacyclovir in experimentally EHV1-infected ponies

Garré

Gryspeerdt

Croubels

et al. 2009

Veterinary Microbiology

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The purpose of the current study was to investigate the therapeutic efficacy of valacyclovir against EHV1 in a controlled study. Eight naïve Shetland ponies were inoculated with 10 6.5 TCID 50 of the neuropathogenic strain 03P37. Four ponies were treated with valacyclovir at a dosage of 40 mg/kg bodyweight, three times daily, for five (n=2) or seven (n=2) consecutive days, while the other 4 ponies served as untreated controls. The treatment regimen started 1 hour before inoculation. Ponies were monitored daily for clinical signs. At 0,

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Section: Introductionmentioning

confidence: 99%

Evaluation of orally administered valacyclovir in experimentally EHV1-infected ponies

Garré

Gryspeerdt

Croubels

et al. 2009

Veterinary Microbiology

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“…However, corticosteroid therapy had not been successful and even worsened the lesions. After diagnosis, the cat was treated topically with aciclovir which was not tolerated (pruritus) and was substituted with L‐lysine integration per os twice daily, because the owners refused treatment with interferon omega. Recovery was slow and complete after three months of treatment.…”

Section: Discussionmentioning

confidence: 99%

Feline herpesvirus ulcerative dermatitis: an atypical case?

Porcellato

Luciani²,

Marenzoni

et al. 2018

Veterinary Dermatology

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“…Some cats with FHV-1-or FCV-associated illnesses have had potential positive responses noted after administration of either feline recombinant IFN-ω (Virbagen Omega; Virbac) or IFN-α2b made for use in humans. [18][19][20] In this study, we chose to use IFN-α2b rather than the feline recombinant product as the feline product is not available in the USA. We also selected the dosage of 10,000 U/kg SC q24h empirically based on unpublished opinions from veterinary clinicians working in this field.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of intranasal vaccine administration and high-dose interferon- α2b therapy for treatment of chronic upper respiratory tract infections in shelter cats

Fenimore

Carter

Fankhauser

et al. 2015

Journal of Feline Medicine and Surgery

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Clinical signs of upper respiratory tract infection can be hard to manage in cats, particularly those in shelters. In this study, clinical data were collected from chronically ill (3-4 weeks' duration) cats with suspected feline herpesvirus-1 (FHV-1) or feline calicivirus (FCV) infections after administration of one of two novel therapies. Group A cats were administered a commercially available formulation of human interferon-α2b at 10,000 U/kg subcutaneously for 14 days, and group B cats were administered one dose of a FHV-1 and FCV intranasal vaccine. Molecular assays for FHV-1 and FCV were performed on pharyngeal samples, and a number of cytokines were measured in the blood of some cats. A clinical score was determined daily for 14 days, with cats that developed an acceptable response by day 14 returning to the shelter for adoption. Those failing the first treatment protocol were entered into the alternate treatment group. During the first treatment period, 8/13 cats in group A (61.5%) and all 12 cats in group B (100%) had apparent responses. The seven cats positive for nucleic acids of FHV-1 or FCV responded favorably, independent of the treatment group. There were no differences in cytokine levels between cats that responded to therapy or failed therapy. Either protocol assessed here may be beneficial in alleviating chronic clinical signs of suspected feline viral upper respiratory tract disease in some cats that have failed other, more conventional, therapies. The results of this study warrant additional research involving these protocols.

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Feline herpes dermatitis treated with interferon omega

Abstract: This case report describes the diagnosis, demonstration and treatment of feline herpes virus-induced facial dermatitis in a cat. The cat was successfully treated with interferon omega (IFN-omega).

Cited by 24 publications

References 25 publications

Evaluation of orally administered valacyclovir in experimentally EHV1-infected ponies

Evaluation of orally administered valacyclovir in experimentally EHV1-infected ponies

Feline herpesvirus ulcerative dermatitis: an atypical case?

Evaluation of intranasal vaccine administration and high-dose interferon- α2b therapy for treatment of chronic upper respiratory tract infections in shelter cats

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