Feeling Fine

Walter, Jennifer; Kahn, Stacy A.; Noe, Joshua D.; Schurman, Jennifer Verrill; Miller, Steve; Greenley, Rachel Neff

doi:10.1097/mib.0000000000000657

Cited by 33 publications

(22 citation statements)

References 32 publications

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“…Further, internalizing symptoms such as depression and anxiety are found to be independently associated with recurrence of IBD in adult population [1517]. The prevalence of depression varies anywhere between 13% in disease remission state to as high as 60% in patients with disease activity [38161819202122]. In our study, the prevalence of depression is estimated to be 13% amongst IBD patients and the single largest contributor of psychiatric disorders in our cohort followed by anxiety −12.7%.…”

Section: Discussionmentioning

confidence: 70%

“…Studies have shown the presence of internalizing symptoms is a strong predictor of health-related quality of life. Walter et al [16], reported that depression and anxiety are also associated with perceived functional disability in patients who are having clinical remission. Further, internalizing symptoms such as depression and anxiety are found to be independently associated with recurrence of IBD in adult population [1517].…”

Section: Discussionmentioning

confidence: 99%

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Burden of Psychiatric Disorders among Pediatric and Young Adults with Inflammatory Bowel Disease: A Population-Based Analysis

Thavamani

Umapathi

Khatana

et al. 2019

Pediatr Gastroenterol Hepatol Nutr

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PurposeThere is increasing prevalence of psychiatric disorders among inflammatory bowel Disease (IBD) population. Further, presence of psychiatric disorders has been shown as an independent predictor of quality of life among patients with IBD. We intended to explore the prevalence of various psychiatric disorders among pediatric and young adult population with IBD as a population-based analysis.MethodsWe did a retrospective case control analysis using a deidentified cloud-based database including health care data across 26 health care networks comprising of more than 360 hospitals across USA. Data collected across different hospitals were classified and stored according to Systematized Nomenclature of Medicine-Clinical Terms. We preidentified 10 psychiatric disorders and the queried the database for the presence of at least one of the ten psychiatric disorders among IBD patients between 5 and 24 years of age and compared with controls.ResultsTotal of 11,316,450 patients in the age group between 5 and 24 years and the number of patients with a diagnosis of IBD, Crohn's disease or ulcerative colitis were 58,020. The prevalence of psychiatric disorders was 21.6% among IBD mainly comprising of depression and anxiety disorder. Multiple logistic regression analysis showed, IBD is 5 times more likely associated with psychiatric disorders than controls, p<0.001). We showed a steady increasing trend in the incidence of psychiatric disorders among IBD patients (2% in 2006 to 15% in 2017).ConclusionLargest population-based analysis demonstrated an increased prevalence of psychiatric disorders among IBD patients. Our study emphasizes the need for psychological and mental health services to be incorporated as a part of the routine IBD clinic.

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Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

Burden of Psychiatric Disorders among Pediatric and Young Adults with Inflammatory Bowel Disease: A Population-Based Analysis

Thavamani

Umapathi

Khatana

et al. 2019

Pediatr Gastroenterol Hepatol Nutr

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“…The authors attributed this unexpected finding to the excellent social support in the young patients’ environment [ 41 ]. Walter et al [ 48 ], on the basis of a careful examination of the literature, noted that older studies (1989 – 2004) reported higher depression rates; subsequent advances in treatment may be responsible for the lower levels of psychological distress observed more recently. Therefore, we suggest that screening and treatment for mental wellbeing should be implemented especially for those with increased disease activity and potentially weaker social support.…”

Section: Discussionmentioning

confidence: 99%

Psychological wellbeing and physical activity in children and adolescents with inflammatory bowel disease compared to healthy controls

et al. 2017

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BackgroundChildren and adolescents with inflammatory bowel disease (IBD) report impairments in daily activities, social interactions and coping. Findings regarding psychological functioning are inconsistent, while limited information is available on objectively assessed physical activity (PA). The aims of the present study were therefore to compare anthropometric dimensions, blood values, psychological functioning and PA of children and adolescents with IBD with healthy controls.MethodsForty-seven children and adolescents took part in the study. Of these, 23 were diagnosed with IBD (mean age: 13.88 years, 44% females). The IBD group was divided into a medically well adjusted “remission-group” (n = 14; IBD-RE) and a group with an “active state” of disease (n = 8; IBD-AD). Healthy controls (n = 24; HC) were age- and gender-matched. Participants’ anthropometric data, blood values and objective PA were assessed. Further, participants completed questionnaires covering socio-demographic data and psychological functioning.ResultsParticipants with IBD-AD showed higher erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) values, haemoglobin, and leukocyte values. IBD-AD had poorer psychological functioning and lower PA (average steps per day) compared to IBD-RE and HC. No mean differences were found between IBD-RE and HC.ConclusionsThe pattern of results suggests that effective medical treatment of IBD in children and adolescents is associated with favorable physiological parameters, psychological dimensions and PA. Psychological counselling of children and adolescents in an active state of IBD seem to be advised in addition to standard treatment schedules.Trial registrationNCT NCT02264275; Registered 8 October 2014.

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“…However, the impact of IBD on an adolescent patients' quality of life extends beyond their standard medical care. Adolescent patients with IBD are at an increased risk of depression and poor adherence to treatment plans [4][5][6]. This poor adherence exacerbates disease activity, results in lapses in care, and predisposes patients to preventable complications [7].…”

Section: Introductionmentioning

confidence: 99%

Evaluating a Standardized Transition of Care Process for Pediatric Inflammatory Bowel Disease Patients

et al. 2020

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To reduce lapses in care for pediatric inflammatory bowel disease (IBD) patients approaching adulthood, a health maintenance transition visit (HMV) was developed to supplement standard medical care (SMV). Our aim was to assess the effect of the HMV on transition readiness. A retrospective chart review was conducted at a single center with demographics and clinical data from HMV and SMV visits. Effectiveness of the HMV was assessed by the patient health questionanaire-9 (PHQ-9) and transition readiness assessment questionnaire (TRAQ) scores. A total of 140 patients, 80% Caucasian and 59% male completed an HMV. The mean age was 18 ± 2 years old, and 93% of patients reported inactive or mild disease. Patients who completed at least 1 prior HMV scored significantly higher on the TRAQ when transferring to adult care compared to patients transferred at their first HMV visit (92 vs. 83, p < 0.05). Of patients with no prior depression diagnosis, 36% had a positive screen for depression. A significant relationship was identified between disease status and PHQ-9 (p < 0.05). This study demonstrated a structured HMV increased transition readiness and quantified the significant under-diagnosis of depression in this population, emphasizing the importance of screening. These results indicate depression may affect patients’ transition preparedness.

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Feeling Fine

Abstract: Current results highlight the need to look beyond disease severity and examine the perception of functional disability of patients with IBD when seeking to identify youth at risk for internalizing symptoms such as depression and anxiety.

Cited by 33 publications

References 32 publications

Burden of Psychiatric Disorders among Pediatric and Young Adults with Inflammatory Bowel Disease: A Population-Based Analysis

Burden of Psychiatric Disorders among Pediatric and Young Adults with Inflammatory Bowel Disease: A Population-Based Analysis

Psychological wellbeing and physical activity in children and adolescents with inflammatory bowel disease compared to healthy controls

Evaluating a Standardized Transition of Care Process for Pediatric Inflammatory Bowel Disease Patients

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