Febrile responses of bluegill (Lepomis macrochirus) to bacterial pyrogens

Reynolds, William W.; Casterlin, Martha E.; Covert, Jerry B.

doi:10.1016/0306-4565(78)90006-2

Cited by 28 publications

(6 citation statements)

References 8 publications

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“…Cold-blooded animals, such as fish, cannot do this, but they can raise their body temperatures by moving to warmer areas (Reynolds et al, 1976). Such a behavioral fever response to infection has been previously described in many fish species, including the bluegill and goldfish (Reynolds et al, 1978), Mozambique tilapia (Tsai et al, 2012), Nile tilapia (Cerqueira et al, 2016), rainbow trout (Grans et al, 2012), and zebrafish (Boltana et al, 2013). Fish exhibit behavioral fever responses to a range of pathogens, including parasites.…”

Section: Introductionmentioning

confidence: 72%

Temperature preference of cave and surface populations of Astyanax mexicanus

Tabin

Aspiras

Martineau

et al. 2018

Developmental Biology

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Little is known about the genetic basis of behavioral choice, such as temperature preference, especially in natural populations. Thermal preference can play a key role in habitat selection, for example in aquatic species. Examining this behavior on a genetic level requires access to individuals or populations of the same species that display distinct temperature preferences. Caves provide a uniquely advantageous setting to tackle this problem, as animals colonizing caves encounter an environment that generally has a different, and far more stable, annual temperature than what is encountered on the outside. Here, we focus on cave and surface populations of Astyanax mexicanus, the Mexican tetra, and examine temperature preference and strength of temperature preference (reflected in the percent of time spent at the optimal temperature). We used a tank with a stable temperature gradient and automated tracking software to follow individual fish from each population. We found that distinct populations of A. mexicanus display differences in both temperature preference and strength of preference. Hybrid crosses established that these are multigenic traits that segregate independently from one another. Temperature preference in many aquatic animals is known to shift towards warmer temperatures following infection with parasites (akin to a fever response in humans). While surface fish infected by the ectoparasite Gyrodactylus turnbulli (a gill fluke) displayed a strong fever response, cavefish showed a significantly attenuated fever response. This work establishes A. mexicanus as a genetically tractable system in which differences in temperature preference can be studied in naturally evolved populations.

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Section: Introductionmentioning

confidence: 72%

Temperature preference of cave and surface populations of Astyanax mexicanus

Tabin

Aspiras

Martineau

et al. 2018

Developmental Biology

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“…Positive Effekte Fieber als eine Reaktion des Organismus auf eine Infektion ist im Tierreich weit verbreitet. So konnte am Tiermodell gezeigt wer− den, dass sowohl Reptilien [29,30], Amphibien [31], Fische [32,33], Arthropoden [34,35], Vögel [36] und verschiedene Säu− getiere [37,38,25] Bei kardiopulmonalen Risikopatienten, Schwangeren im ersten Trimenon, Kleinkindern mit Fieberkrämpfen in der Anamnese und bei Erkrankungen des zentralen Nervensystems ist jedoch eine zügige und suffiziente antipyretische Therapie erforderlich. Dabei gilt zu beachten, dass die Gabe von Antipyretika in Abwä− gung ihrer Nebenwirkungen die Therapie der Wahl ist.…”

Section: Die Bedeutung Von Fieberunclassified

“…Während Warmblüter in der Lage sind, ihre Körpertemperatur durch Steigerung der Wärmeproduktion zu erhöhen, reagieren Kaltblüter bei Infektionen mit einer in− stinktiven Suche nach wärmerer Umgebung. Zum Beispiel stei− gern Goldfische nach intraperitonealer Infektion mit Aeromonas hydrophilia durch das Aufsuchen wärmerer Wasserregionen ihre Körperkerntemperatur von 27,9 auf 32,7 8C[32]. Eines der be− kanntesten und meist zitierten Tierexperimente sind die von Kluger et al[39].…”

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Fieber in der Intensivmedizin

Brüderlein

Strupp²,

Vagts³

2006

Anästhesiol Intensivmed Notfallmed Schmerzther

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Fever is an unspecific symptom of most intensive care patients during their stay on an intensive care unit. The reasons for the increase of body temperature often remain unclear, even extended diagnostic measures are performed. The pathogenetic relevance of fever is commonly underestimated and leads to unreflected treatment of every increase of body temperature above 38 C. But the development of fever in patients is quite often useful and should not be treated with antipyretics. Physical measures like ice packs and surface cooling are only allowed to be used, if the central set point is lower than the actual core body temperature. This gradient can be recognized, when the patient starts to sweat. Principally, the treatment of fever in cardiovascular risk patients, patients with high risk for adverse neurological outcome, pregnant women during the first trimenon and in children with seizures must start with pharmacological interventions,which can be followed by physical measures.

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“…Others have investigated a wide range of biological effects produced by endotoxin in fish, including lethality (Berczi et al, 1966;Pol and Berg-Blommaert, 1980), antibody response (Paterson and Fryer, 1974;Ingram and Alexander, 1980), pyrogenicity (Reynolds et al, 1977), hepatic glycogenolysis (Wedemeyer and Ross, 1968), and pituitary activation (Wedemeyer, 1969). In vitro, endotoxin was inactivated by fish serum (Von Eschen and Rudbach, 1974) and induced consumption of complement in fish serum (Day et ai, 1970).…”

Section: Introductionmentioning

confidence: 99%

THE EFFECTS OF MULTIPLE INJECTIONS OF BACTERIAL ENDOTOXIN ON BLOOD COAGULATION IN THE TOADFISH,OPSANUS TAU

Miller¹,

Levin²

1984

The Biological Bulletin

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The effects of multiple injections of bacterial endotoxin on blood coagulation in the toadfish, Opsanus tan, were studied. Preparations of endotoxin from Escherichia coli, Aeromonas hydrophila, or Vibrio harveyi (strain 392) were utilized. Three injections of endotoxin were administered at either 6 or 12 h intervals.Although there was a slight decrease in plasma fibrinogen concentration following the administration of endotoxin, levels did not significantly differ from normal controls. Endotoxins from E. coli and A. hydrophila initially shortened the prothrombin time (PT), but subsequently the PT returned to normal. In contrast, the partial thromboplastin time (PTT) was not shortened following the administration of bacterial endotoxin. There was no detectable effect on the plasma recalcification time. There were no significant differences between the red and white blood cell levels of control fish and fish that had received endotoxin. Endotoxins from A. hydrophila and V. harveyi reduced the survival of recipient toadfish, whereas E. coli did not increase mortality during the period of observation. Although both control and experimental fish demonstrated increased hematopoietic activity in the kidney, only O. tan that had received endotoxin demonstrated marked necrosis of interstitial cells.Our data indicate that multiple injections of bacterial endotoxin into the toadfish result in alterations of blood coagulation compatible with activation of the blood coagulation mechanism. However, striking evidence of a consumptive coagulopathy, as is observed in mammals following multiple injections of bacterial endotoxin, was not observed. Interestingly, toadfish tolerated doses of endotoxin markedly greater than those sufficient to produce not only alterations of blood coagulation but also rapid death in many mammalian species.

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Febrile responses of bluegill (Lepomis macrochirus) to bacterial pyrogens

Cited by 28 publications

References 8 publications

Temperature preference of cave and surface populations of Astyanax mexicanus

Temperature preference of cave and surface populations of Astyanax mexicanus

Fieber in der Intensivmedizin

THE EFFECTS OF MULTIPLE INJECTIONS OF BACTERIAL ENDOTOXIN ON BLOOD COAGULATION IN THE TOADFISH,OPSANUS TAU

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