Febre de origem indeterminada em adultos

Lambertucci, José Roberto; Ávila, Renata Eliane de; Voieta, Izabela

doi:10.1590/s0037-86822005000600012

Cited by 6 publications

(6 citation statements)

References 19 publications

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“…It is always worth inquiring about symptoms that may be considered unimportant, such as jaundice, weight loss, chronic cough, and change in bowel movements, associated with the fever. The personal and family history of previous diseases can also provide valuable indications of specific etiologies (mainly autoimmune diseases) 8 . Up to 28% of travelers who return to their place of origin report fever as the main complaint in medical consultations 13 .…”

Section: Clinical Historymentioning

confidence: 99%

“…The naproxen test can be useful in the differential diagnosis of FUO, although there is controversy among some authors 2. 8 . The test is based on the answer to the empirical therapy with naproxen in patients with prolonged fever (for at least seven days).…”

Section: Naproxen Testmentioning

confidence: 99%

“…biopsies). There is a recommendation to perform bone marrow biopsies, even in the absence of changes in peripheral blood 8 .…”

Section: Laboratory Testsmentioning

confidence: 99%

“…Despite a large number of diagnostic resources, meticulous clinical examination is still the fundamental approach to patients with prolonged fever. Empirical therapy is performed only in selected cases, since some medications may mask symptoms and interfere with the early etiological diagnosis, diagnostic investigation 1, 8 . One of the most accepted concepts of classical FUO encompasses axillary temperature ≥37.8 ºC on several occasions, for a period ≥ three weeks, with no diagnosis after three days of hospital investigation or three outpatient consultations 8.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Fever of unknown origin – a literature review

Santana

Rodrigues

Silva

et al. 2019

Rev. Assoc. Med. Bras.

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Fever of undetermined origin (FUO) is a challenging entity with a striking presence in hospitals around the world and can be associated with a myriad of differential diagnoses. It is defined as axillary temperature ≥ 37.8 ° C on several occasions, lasting ≥ three weeks, in the absence of diagnosis after three days of hospital investigation or three outpatient visits. The main etiologies are: infectious, neoplastic, and rheumatic. The diagnosis is based on the detailed clinical history and physical examination of these patients, in order to direct the specific complementary tests to be performed in each case. Empirical therapy is not recommended (with few exceptions) in patients with prolonged fever, as it may disguise and delay the diagnosis and conduct to treat the specific etiology. The prognosis encompasses mortality of 12% -35%, varying according to the underlying etiology. In this sense, the objective of this study is to review the main topics about fever of undetermined origin, bringing historical and scientific aspects, national and international.

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Section: Clinical Historymentioning

confidence: 99%

Section: Naproxen Testmentioning

confidence: 99%

“…biopsies). There is a recommendation to perform bone marrow biopsies, even in the absence of changes in peripheral blood 8 .…”

Section: Laboratory Testsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Fever of unknown origin – a literature review

Santana

Rodrigues

Silva

et al. 2019

Rev. Assoc. Med. Bras.

View full text Add to dashboard Cite

show abstract

“…Fever of unknown origin (FUO) is a clinical entity that is highly prevalent worldwide and affects all age groups, with some peculiarities at extreme ages and in special groups. [1][2][3][4] Most of the times, it is associated with infectious, neoplastic, and rheumatological etiologies. A meticulous clinical examination is still the foundation for approaching patients with prolonged fever, despite a large number of diagnostic resources.…”

Section: Introductionmentioning

confidence: 99%

Fever of unknown origin in special groups

Santana

Rodrigues

Silva

et al. 2019

Rev. Assoc. Med. Bras.

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SUMMARY Fever of undetermined origin (FUO) is a challenging entity with a striking presence in hospitals around the world. It is defined as temperature ≥ 37.8 ° C on several occasions, lasting ≥ three weeks, in the absence of diagnosis after three days of hospital investigation or 3 outpatient visits. The main etiologies are infectious, neoplastic, and non-infectious inflammatory diseases. The diagnosis is based on the detailed clinical history and physical examination of these patients, in order to direct the specific complementary tests to be performed in each case. The initial diagnostic approach of the FUO patient should include non-specific complementary exams. Empirical therapy is not recommended (with few exceptions) in patients with prolonged fever, as it may disguise and delay the diagnosis and conduct to treat the specific etiology. The prognosis encompasses mortality of 12-35%, varying according to the baseline etiology.

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Prevalence and epidemiological characteristics of human immunodeficiency virus-1 infection in an iron mining area with intense migratory flow in Pará State, Brazilian amazon, 2005–2014

et al. 2020

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Acquired immunodeficiency syndrome (AIDS) caused by human immunodeficiency virus (HIV) is a major global public health problem. The aim of this study is to determine the prevalence of HIV-1 infection in four municipalities of Pará State (Marabá, Parauapebas, Curionópolis, and Canaã dos Carajás), in northern, Brazil. The municipalities are located in the Carajás Complex iron mining area. The employment opportunities result in extensive migratory flow of people. A total of 4771 serum samples were obtained from 2005 to 2014 and were sent to Evandro Chagas Institute, Belém-Pará, where they were tested by enzymelinked immunosorbent assay, with reactive samples confirmed by Western blot analysis. The samples were from individuals from 23 Brazilian states and the Federal District, mainly Maranhão (39.53%) and other municipalities of Pará (34.25%). The total positivity rate was 0.48% (23/4771). The rate was 0.47% (14/2975) in males and 0.50% (9/1796) in females. Of these, 0.33% (14/ 4275) were from asymptomatic individuals whose serum were collected during the serological survey, 1.81% (9/497) were from cases featuring clinical symptoms including fever/diarrhea/jaundice, which were included in febrile, diarrheal, and icteric syndromes analyzed during the study. The findings indicated the presence of HIV-1 infection in the general population studied. The majority of cases (60.9%, 14 of 23 positive cases) were asymptomatic.

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Febre de origem indeterminada em adultos

Cited by 6 publications

References 19 publications

Fever of unknown origin – a literature review

Fever of unknown origin – a literature review

Fever of unknown origin in special groups

Prevalence and epidemiological characteristics of human immunodeficiency virus-1 infection in an iron mining area with intense migratory flow in Pará State, Brazilian amazon, 2005–2014

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