Features of White Rats Stomach Anatomical Structure

Гринь, Володимир Григорович; Костиленко, Ю П; Ячмінь, Анастасія Ігорівна

doi:10.26724/2079-8334-2019-1-67-133

Cited by 3 publications

(2 citation statements)

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“…Отже, завдання зводиться насамперед до вибору найбільш відповідного виду лабораторних тварин, причому вирішальним чинником є мінімальність витрат при утриманні даних тварин і проведенні над ними експериментальних досліджень. Згідно з даними літератури, з метою експериментального моделювання перитонітів найбільш прийнятними є білі щури, оскільки вони у порівнянні з людиною мають подібну анатомічну будову внутрішніх органів [14][15][16][17][18][19][20].…”

Section: великий чепець білих щурів: структурно-функціональна характе...unclassified

The Greater Omentum of White Rats: Structural and Functional Characteristics and its Role in Peritonitis

Maksymenko¹,

Гринь²

2023

Ukr. ž. med. bìol. sportu

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The greater omentum is now recognized as an important organ in the fight against intra-abdominal infections, so it is often called the “policeman of the peritoneal cavity”. The greater omentum plays the most important role in the implementation of immune supervision of the antigenic condition of the peritoneal fluid and rapid response of damage to the gastrointestinal tract, which is often complicated by inflammation of the peritoneum – peritonitis. The purpose of the work was to study the peculiarities of the structure of the greater omentum of white rats and its role in peritonitis by means of a bibliographic analysis of the literature. Materials and methods. This bibliographic analysis is based on published articles, books, textbooks, monographs and dissertation abstracts. For the purposes of this systematic review, a literature search was carried out in the worldwide Internet, domestic sources of literature, scientific and electronic library of Poltava State Medical University using the following key words: “morphology”, “comparative anatomy”, “greater omentum”, “greater omentum of the rats”, “immune system”, “white rats”, “laboratory animals”, “rat anatomy”, “peritonitis”. Results and discussion. The greater omentum of white rats and humans are represented by two different structures: translucent membranous regions and regions rich in adipose tissue. According to the literature, the greater omentum of white rats is the main morphological characteristic (in miniature), homologous to the human one. The main function of the greater omentum, according to the opinion of many authors and ours too, is immunity. Immune structures of the greater omentum of white rats are represented by lymphoid nodules, known in the literature as milky spots, most of which are located near arteries and veins. In pathological conditions, the greater omentum acquires absolutely special properties, such as plasticity, the ability to fuse with a traumatic and inflamed surface, the ability to hemostasis and phagocytosis, the ability to germinate and revascularize, to absorb fluids and microparticles from the peritoneal cavity, and the ability to the immunological response. Conclusion. According to the literature, the greater omentum of white rats is a miniature likeness of the greater omentum of a person. However, unlike the latter, it consists of only one duplication of the visceral peritoneum, between the leaves of which there are blood vessels with deposits of adipose tissue and milk spots. Thus, the greater omentum of white rats is a perfectly acceptable object of experimental research with the subsequent legitimate extrapolation of their results to humans. The greater omentum occupies a central place in the peritoneal defense mechanisms due to its innate immune function, high absorbing capacity, and ability to attach to neighboring structures to close defects of abdominal organs and promote their healing, due to its expressive angiogenic activity

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Section: великий чепець білих щурів: структурно-функціональна характе...unclassified

The Greater Omentum of White Rats: Structural and Functional Characteristics and its Role in Peritonitis

Maksymenko¹,

Гринь²

2023

Ukr. ž. med. bìol. sportu

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“…In the available literature, data are available on the morphological features of the structure of both the middle section of the digestive tube as a whole and its individual parts [3,4,5,6,7,8]. However, these studies relate to the morphology of the rat digestive tube, and the structural features of the rabbit ileum have not been studied.…”

Section: Introductionmentioning

confidence: 99%

Structural organization of the ileum of laboratory animals in normal and in a comparative view aspect

Sydorenko

2019

Rep. of Morph.

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In recent decades, diseases of the digestive system that require immediate, both therapeutic and surgical treatment, have become widespread, and it is therefore a natural task to find new and optimize existing technologies and methods for correcting the above-mentioned nosologies. Preclinical studies of such developments are conducted exclusively on laboratory animals and knowledge of the morphological features of their structure for further comparison with the morphology of similar human organs is an urgent task of modern medical and biological science. The purpose of the study was to study the structural organization of the ileum of rabbits in comparative species and to obtain control data on its morphological features. Adequate research methods were used in the work according to the set goal, namely: histological, histochemical, electron microscopic, morphometric and statistical and biopsies of the ileum of 10 rabbits were studied. The correctness of the distribution of traits by each of the variations obtained, the average values for each trait studied, standard errors and standard deviations were evaluated. The significance of the difference of values between independent micrometric values in the normal distribution of features was determined by Student’s criterion. The paper describes the main structural components of the ileum of rabbits and compared with similar structures of the human ileum. The ileum of rabbits, as in humans, has been determined to have four membranes: mucous, submucosal, muscular and serous. The mucous membrane is constructed from the epithelial layer, which is located on the basement membrane and the muscular plate and contains cellular elements (exocrinocytes, enterocytes of various kinds, elements of the diffuse endocrine system associated with the mucous membrane, intraepithelial lymphocytes), blood and lymphatic vessels and nerve endings. The submucosa is composed of loose fibrous connective tissue, which contains collagen and reticular fibers, elements of diffuse lymphoid tissue, blood vessels, and nerve endings. The muscular and serous membranes are constructed in the same way as in the human ileum. Thus, after the study, it was determined that the morphological organization of the ileum of rabbits at the optical and electron microscopic levels has general patterns of structure similar to those in the ileum of the person.

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Macro-Microscopic Features of the Relief of the Mucous Membrane of the Gastrointestinal Tract of White Rats

Гринь

2019

WOMAB

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Features of White Rats Stomach Anatomical Structure

Cited by 3 publications

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The Greater Omentum of White Rats: Structural and Functional Characteristics and its Role in Peritonitis

The Greater Omentum of White Rats: Structural and Functional Characteristics and its Role in Peritonitis

Structural organization of the ileum of laboratory animals in normal and in a comparative view aspect

Macro-Microscopic Features of the Relief of the Mucous Membrane of the Gastrointestinal Tract of White Rats

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