Features of Menstrual and Generative Function Disorders in Depressive Disorders of Endogenous Nature

Белов, О. О.; Kostyuk, Alevtina L; Andriichuk, Vitalii M; Kostyuk, Irina

doi:10.26724/2079-8334-2020-4-74-15-19

Cited by 1 publication

(1 citation statement)

References 11 publications

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“…According to the World Health Organization (WHO), major depressive disorder (MDD) will be the most significant cause of disease burden worldwide by 2030 [101]. The monoamine hypothesis was one of the initial hypotheses for the breakdown of neurotransmission in MDD.…”

Section: Gut Microbiota and Psychiatric Disorders 101 Major Depressiv...mentioning

confidence: 99%

The Effect of Probiotic Supplementation on the Gut–Brain Axis in Psychiatric Patients

Sabit,

Kassab,

Alaa

et al. 2023

CIMB

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The pathophysiology of several psychiatric diseases may entail disturbances in the hypothalamic–pituitary–adrenal (HPA) axis and metabolic pathways. Variations in how these effects present themselves may be connected to individual variances in clinical symptoms and treatment responses, such as the observation that a significant fraction of participants do not respond to current antipsychotic drugs. A bidirectional signaling pathway between the central nervous system and the gastrointestinal tract is known as the microbiota–gut–brain axis. The large and small intestines contain more than 100 trillion microbial cells, contributing to the intestinal ecosystem’s incredible complexity. Interactions between the microbiota and intestinal epithelium can alter brain physiology and affect mood and behavior. There has recently been a focus on how these relationships impact mental health. According to evidence, intestinal microbiota may play a role in neurological and mental illnesses. Intestinal metabolites of microbial origin, such as short-chain fatty acids, tryptophan metabolites, and bacterial components that might stimulate the host’s immune system, are mentioned in this review. We aim to shed some on the growing role of gut microbiota in inducing/manipulating several psychiatric disorders, which may pave the way for novel microbiota-based therapies.

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Section: Gut Microbiota and Psychiatric Disorders 101 Major Depressiv...mentioning

confidence: 99%

The Effect of Probiotic Supplementation on the Gut–Brain Axis in Psychiatric Patients

Sabit,

Kassab,

Alaa

et al. 2023

CIMB

View full text Add to dashboard Cite

show abstract

Features of Menstrual and Generative Function Disorders in Depressive Disorders of Endogenous Nature

Cited by 1 publication

References 11 publications

The Effect of Probiotic Supplementation on the Gut–Brain Axis in Psychiatric Patients

The Effect of Probiotic Supplementation on the Gut–Brain Axis in Psychiatric Patients

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