The aim: of the study is to study the features of the clinical phenomenology of depressive disorders at the present stage, taking into account gender and age factors. Materials and methods: Clinically examined 107 men and 138 women with bipolar affective disorder (current episode of depression), depressive episode and recurrent depressive disorder using HDRS, HARS, BDI, C. Spilberger’s Scale of Reactive and Personality Anxiety. Results: In all patients showed an increase in the severity of depression and anxiety with age, but in women the greatest differences were found between the middle and older age groups, and in men when comparing young and middle age groups. In young patients the level of agitated depression is higher for men, and women showed the higher overall level of anxiety, somatic anxiety, undifferentiated depression, reactive and personality anxiety. In patients aged 30-44, men have a significantly higher overall score of HARS depression, the level of adynamic, agitated and undifferentiated depression, the level of depression on BDI. In the older age group, the levels of depression in men and women are not significantly different, and the levels of mental anxiety and personality anxiety in women are significantly higher. Conclusions: The general tendency consisting in increasing the severity of depression with age, and more pronounced indicators of depression in men, and anxiety in women. In men, the greatest increase in the severity of depression occurs before the age of 44 years, and in women after 45 years.

The aim: Was exploring features of psychopathological reaction in parents whose children suffer from chronic musculoskeletal disorders. Materials and methods: Clinically, 40 fathers and 64 mothers of children suffering from chronic muscular motor pathologies using M. Hamilton’s Depression and Anxiety Scale and Buss-Durkee Hostility Invertory were examined. Results: It was revealed that the foundation of psychopathological reactions of parents to the chronic illness of children is depressive (from 68,2% to 97,0%) and anxiety (from 40.9% to 100.0%) disorders, and dyssomic disorders as well (from 18.2% to 93.9%), asthenic (from 9.1% to 81.8.%), affective lability (from 9.1% to 36.4%), apathetic (from 4.5% to 42.4%), cognitive (from 4.5% to 42.4%) and obsessive-phobic (from 4.5% to 39.4%) disorders. Mothers with longer and shorter periods of illness in children showed higher levels of depression (20.82 ± 5.94 and 20.26 ± 6.59 respectively) and anxiety (19.06 ± 5.00 and 17, 77 ± 5.65) compared with fathers (17.44 ± 8.78 and 10.82 ± 6.21, respectively; 14.72 ± 5.57 and 14.95 ± 4.45), but fathers showed higher levels of aggression 65.59 ± 10.42 and 63.21 ± 10.31 (respectively versus 55.27 ± 6.97 and 49.72 ± 10.00). Conclusions: А high level of psychopathological reaction in mothers is detected at short periods of disease, and in fathers it significantly grows as the duration of child’s illness increases.

The aim: To examine the features of depressive and anxiety phenomenology in lung cancer, taking into account the gender factor. Materials and methods: 112 patients with a primary diagnosis of stage II and III lung cancer were clinically and psychologically examined using HDRS, HARS, BDI, C. Spilberger’s Reactive and Personality Anxiety Scale. Results: It was found that the core affective psychopathological symptoms of patients with lung cancer are manifestations of depression (96.3% of men, 96.8% of women (p> 0.05), 96.4% together) and anxiety (77.8% , 93.5% (p<0.05) and 82.1%) in combination with asthenic-neurotic (67.9%, 61.3% (p> 0.05) and 66.1%) and affective labile (54.3%, 61.3% (p> 0.05) and 56.2%) manifestations; additional symptoms are apathetic (25.9%, 9.7% (p<0.05) and 21.4%), obsessive (19.8%, 38.7% (p<0.05) and 25.0%) and dysphoric (23.5%, 6.5% (p<0.05) and 18.7%) manifestations. The severity of depressive and anxiety of women is higher than of men; the severity of depressive-anxiety manifestations corresponds to a moderate level: depression by HDRS - 11.6±1.7 points, 15.6±6.3 points (p<0.05) and 12.7±4.0 points; BDI depression – 15.7±6.3 points, 23.7±13.9 points (p<0.05) and 17.9±9.7 points; HARS anxiety - 9.3±2.8 points, 11.5±3.7 points (p<0.05) and 9.9±3.2 points, and reactive anxiety - 44.4±11.1 points, 47.9±15.5 points (p<0.05) and 45.4±12.5 points. The identified differences can be explained by different gender models of psychological response. Conclusions: The core affective symptoms of patients with lung cancer are manifestations of depression and anxiety in combination with asthenic-neurotic and affective-labile manifestations; additional are apathetic, obsessive and dysphoric manifestations.

Experience, current situation and the prospects for operation of mining and processing enterprises for production of montan wax from brown coal are analyzed. Classification of the main technologies for the use of solid fossil fuel mineral has been performed. The features the technological process for production of montan wax, taking into account the experience of leading enterprises in Germany and Ukraine, are considered. Prospective directions for renewing the production of montan wax on the basis of brown coal reserves of Dneprovskiy brown coal basin are indicated. The evaluation of the attractiveness of production montan wax with the application of cash flow projection methods was carried out. Recommendations on the integrated development of brown coal deposits and processing of brown coal in order to attract foreign investment and support the competitiveness of the country's market have been developed.

Introduction: Depressive disorders are one of the most complex and pressing problems of modern psychiatry; important scientific and practical importance is the study of the pathomorphosis of depression. The aim of the study is to study the features of clinical pathomorphosis of depressive disorders, taking into account the age factor. Materials and methods: Medical documentation of 115 men and 121 women with depressive disorders who applied for psychiatric care in 1971–1995 were studied, and 81 men and 108 women with similar depressive disorders who applied for medical care in 2015–2018 were examined clinically. Results and conclusions: In modern patients, pathomorphosis is most pronounced in young patients (under 30 years of age): asthenia and pessimism were more common in them (65.9% versus 81.9%, p<0.05), suicidal thoughts (52.7% versus 68,7%, p<0.05), dyssomnias. In this age group, there was a decrease in anesthetic symptoms (34.8% versus 12.2%, p<0.01) with an increase in depressions with psychopathological symptoms, mainly in the form of obsessions (42.9% versus 59.0%, p<0,05), depressions with disturbances of biological rhythms, mainly in the form of postsomnic disorders (73.6% versus 96.4%, p<0.05), with vegetative-somatic disorders (63.7% versus 79.5%, p<0.05), asthenic (67.0% versus 81.9%, p<0.05) and agitated symptoms (26.4% versus 39.8%, p<0.05). In the middle age group (30-44 years), the share of vital forms of depression in the structure of depressive symptoms decreased (65.8% versus 44.6%, p<0.01) and depressions with senesto-algic symptomatology (6.6% against 9.6%, p<0.05). In patients of the older age group (45 years and more), the main trends in clinical pathomorphosis were a decrease in anhedonia (90.9% versus 70.7%, p<0.01) and low self-esteem (89.4%versus 65.9%, p<0.01), as well as an increase in apathetic depressions (13.6% versus 29.3%, p<0.05). The general tendency of modern pathomorphosis of depressive disorders is the reduction of vital forms of depression with an increase in depressions with asthenic, anxious and somatic symptomatology.