2016
DOI: 10.1016/j.semarthrit.2015.11.003
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Features associated with hematologic abnormalities and their impact in patients with systemic lupus erythematosus: Data from a multiethnic Latin American cohort

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Cited by 49 publications
(49 citation statements)
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“…On the contrary, these patients seem to have mild lupus without a higher frequency of cumulative damage in spite of long disease duration. Reinforcing this finding, cSLE patients with positive anti-Ro antibodies had lower frequency of thrombocytopenia, a known severe manifestation of lupus [19]. Interestingly, the presence of anti-Ro/La/Sm/RNP was previously associated with more benign form of adult lupus nephritis [20].…”
Section: Discussionmentioning
confidence: 54%
“…On the contrary, these patients seem to have mild lupus without a higher frequency of cumulative damage in spite of long disease duration. Reinforcing this finding, cSLE patients with positive anti-Ro antibodies had lower frequency of thrombocytopenia, a known severe manifestation of lupus [19]. Interestingly, the presence of anti-Ro/La/Sm/RNP was previously associated with more benign form of adult lupus nephritis [20].…”
Section: Discussionmentioning
confidence: 54%
“…Similar observations have been described in a China study showing elevated anti-dsDNA titers in 37% SLE patients complicated with Evans syndrome (N=10/27) [ 20 ]. Furthermore, no one has reported the negative impact of the anti-dsDNA antibodies for AIHA patients with SMM or EMH, except for the associations between IgG/IgM ACL antibodies and thrombocytopenia in patients with SLE/APLS [ 21 22 23 ],…”
Section: Discussionmentioning
confidence: 99%
“…Other laboratory markers that may facilitate diagnosis include the presence of hypocomplementaemia, antiphospholipid antibodies, unexplained cytopenia and a positive direct anti‐globulin test result. The latter illustrates the close relationship between immune‐mediated haematological disorders and SLE 13 …”
Section: Diagnosismentioning
confidence: 95%
“…The latter illustrates the close relationship between immune-mediated haematological disorders and SLE. 13 In practice, for general practitioners and other physicians, the diagnosis of SLE should be considered in any patient presenting with inflammatory joint pain with one or more extra-articular features, as arthralgia is one of the most common clinical Summary Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease predominantly affecting women of childbearing age. New classification criteria for SLE have greater sensitivity and therefore improve the diagnostic certainty for some patients, especially those who may previously have been labelled as having undifferentiated symptoms.…”
Section: Diagnosismentioning
confidence: 99%