Feasibility study of a γ-ray detector based on square PSPMT array for breast cancer imaging

Tamda, N.; Bakkali, Aboubakr; Boulahdour, Hatem; Parmentier, Michel; Pousse, A.; Kastler, B.; Chavanelle, J.

doi:10.1016/j.nima.2005.11.186

Cited by 7 publications

(3 citation statements)

References 8 publications

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“…In the last few years, many studies have been carried out on compact position sensitive gamma-ray detectors in order to optimize a gamma camera for nuclear medicine imaging [1][2][3][4][5][6] . Much of the work dealing with the subject, was mainly oriented towards reaching the best intrinsic detector spatial and energy resolution by using the last generation position sensitive photo multiplier tube [7] (PSPMT), on innovative collimator technique [8] , a novel multi-anode readout and an optimized data acquisition system.…”

Section: Introductionmentioning

confidence: 99%

Study of the characteristics of a scintillation array and single pixels for nuclear medicine imaging applications

Zeng

et al. 2009

Chinese Phys. C

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Section: Introductionmentioning

confidence: 99%

Study of the characteristics of a scintillation array and single pixels for nuclear medicine imaging applications

Zeng

et al. 2009

Chinese Phys. C

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“…Economical and practical reasons have therefore lead many research groups to focus on position-sensitive PMTs (PSPMTs) instead of solid-state solutions for the construction of gamma cameras dedicated to organ or small-animal imaging (Sanchez et al 2006, Jeong et al 2004, Loudos et al 2003, Pani et al 2003, Dhanasopon et al 2005, Tamda et al 2006, More et al 2006. Flat-panel PSPMTs in particular can be used to build compact, high-resolution systems at a relatively low cost.…”

Section: Introductionmentioning

confidence: 99%

Monte Carlo simulations of compact gamma cameras based on avalanche photodiodes

Després¹,

Funk²,

Shah³

et al. 2007

Phys. Med. Biol.

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Avalanche photodiodes (APDs), and in particular position-sensitive avalanche photodiodes (PSAPDs), are an attractive alternative to photomultiplier tubes (PMTs) for reading out scintillators for PET and SPECT. These solid-state devices offer high gain and quantum efficiency, and can potentially lead to more compact and robust imaging systems with improved spatial and energy resolution. In order to evaluate this performance improvement, we have conducted Monte Carlo simulations of gamma cameras based on avalanche photodiodes. Specifically, we investigated the relative merit of discrete and PSAPDs in a simple continuous crystal gamma camera. The simulated camera was composed of either a 4 × 4 array of four channels 8 × 8 mm2 PSAPDs or an 8 × 8 array of 4 × 4 mm2 discrete APDs. These configurations, requiring 64 channels readout each, were used to read the scintillation light from a 6 mm thick continuous CsI:Tl crystal covering the entire 3.6 × 3.6 cm2 photodiode array. The simulations, conducted with GEANT4, accounted for the optical properties of the materials, the noise characteristics of the photodiodes and the nonlinear charge division in PSAPDs. The performance of the simulated camera was evaluated in terms of spatial resolution, energy resolution and spatial uniformity at 99mTc (140 keV) and 125I (≈30 keV) energies. Intrinsic spatial resolutions of 1.0 and 0.9 mm were obtained for the APD- and PSAPD-based cameras respectively for 99mTc, and corresponding values of 1.2 and 1.3 mm FWHM for 125I. The simulations yielded maximal energy resolutions of 7% and 23% for 99mTc and 125I, respectively. PSAPDs also provided better spatial uniformity than APDs in the simple system studied. These results suggest that APDs constitute an attractive technology especially suitable to build compact, small field of view gamma cameras dedicated, for example, to small animal or organ imaging.

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“…These PSPMT arrays allow for the measurement of the photon detection position in monolithic scintillation crystals (see ref. [1]) or arrays of pixelated crystals with small pitch [2][3][4][5][6]. Although the dead area at the borders of the PMT is small, the space between adjacent photomultipliers imposes a challenge to spatial resolution and image uniformity in the central region of the reconstructed image.…”

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confidence: 99%

Correction algorithms for signal reduction in insensitive areas of a small gamma camera

et al. 2014

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The radiation sensitive part of the wide-field, small gamma camera Sentinella TM 108 consists of a monolithic, 102 × 102 mm 2 wide CsI(Na) crystal coupled to four position-sensitive photomultipliers. These are read out via a resistor mesh reducing the 256 PMT channels to four digitized values which allow for an image reconstruction, based on polynomials, with high spatial resolution. The sensor areas between neighboring PMTs suffer from reduced detection efficiency for scintillation light. The corresponding lack of signal amplitude translates to a poor uniformity and additional image compression in the border regions of the images after the first step of reconstruction. These effects cannot be completely eliminated by a global calibration procedure alone.We have developed and evaluated two classes of algorithms to compensate for this reduction of signal amplitude. Corrections are applied for each detected event separately, maintaining the real-time capability of the gamma camera. Algorithm 1 is based on a four-parameter, geometric calculation of the four output signals. This model aims to attack the underlying lack of detection efficiency without further assumptions on the true event distribution, preserving the global polynomial image decompression. Algorithm 2, to the contrary, starts from measured reference distributions of point sources which are used to model local deformations and energy loss without further information on the underlying detector geometry. Here too, a good image quality has been obtained after application of the deduced corrections.

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Feasibility study of a γ-ray detector based on square PSPMT array for breast cancer imaging

Cited by 7 publications

References 8 publications

Study of the characteristics of a scintillation array and single pixels for nuclear medicine imaging applications

Study of the characteristics of a scintillation array and single pixels for nuclear medicine imaging applications

Monte Carlo simulations of compact gamma cameras based on avalanche photodiodes

Correction algorithms for signal reduction in insensitive areas of a small gamma camera

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