Feasibility of free-breathing dynamic contrast-enhanced MRI of the abdomen: a comparison between CAIPIRINHA-VIBE, Radial-VIBE with KWIC reconstruction and conventional VIBE

Seo, Nieun; Park, Seong Joon; Kim, Bohyun; Lee, Chang Kyung; Huh, Jimi; Kim, Jeong Kon; Lee, Seung Soo; Kim, In Seong; Nickel, Dominik; Kim, Kyung Won

doi:10.1259/bjr.20160150

Cited by 10 publications

(11 citation statements)

References 19 publications

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“…Our findings are consistent with those in a previous similar study by Wu et al, 11 who compared radial VIBE with conventional T1-TSE and found that radial VIBE was more motion-robust. The motion-robust benefit of radial VIBE has been documented in other anatomic regions as well, such as the abdomen 16 and prostate. 9 The added value of the present study is the application of a novel GRASP-VIBE technique and its direct intraindividual comparison with the conventional T1-TSE for head and neck MR imaging in routine clinical settings.…”

Section: Discussionmentioning

confidence: 98%

Intraindividual Comparison between the Contrast-Enhanced Golden-Angle Radial Sparse Parallel Sequence and the Conventional Fat-Suppressed Contrast-Enhanced T1-Weighted Spin-Echo Sequence for Head and Neck MRI

Hur

Choi

Yoon

et al. 2021

AJNR Am J Neuroradiol

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BACKGROUND AND PURPOSE:The golden-angle radial sparse parallel-volumetric interpolated breath-hold (GRASP-VIBE) sequence is a recently introduced imaging technique with high resolution. This study compared the image quality between conventional fatsuppressed T1-weighted TSE and GRASP-VIBE after gadolinium enhancement in the head and neck region.MATERIALS AND METHODS: Data from 65 patients with clinical indications for head and neck MR imaging between September 2020 and January 2021 were retrospectively reviewed. Two radiologists assessed the overall image quality, overall artifacts, and image conspicuities in the oropharynx, hypopharynx, and cervical lymph nodes according to 5-point scores (best score: 5). Interobserver agreement was assessed using weighted k statistics. The SNR and contrast-to-noise ratio were calculated and compared between the 2 sequences using a paired Wilcoxon signed rank test.

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Section: Discussionmentioning

confidence: 98%

Intraindividual Comparison between the Contrast-Enhanced Golden-Angle Radial Sparse Parallel Sequence and the Conventional Fat-Suppressed Contrast-Enhanced T1-Weighted Spin-Echo Sequence for Head and Neck MRI

Hur

Choi

Yoon

et al. 2021

AJNR Am J Neuroradiol

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“…DCE-MRI studies with quantitative endpoints are being evaluated in multicenter clinical trials of other cancers, such as prostate and breast cancer (31)(32)(33)(34). Quantitative DCE-MRI in human abdominal applications including PDA will be facilitated by motion-robust, rapid imaging techniques and their feasibility in the clinic has been shown (35)(36)(37). A standardized clinical DCE-MRI protocol (38) is expected to help control data variability across centers.…”

Section: Discussionmentioning

confidence: 99%

Dynamic Contrast-enhanced MRI Detects Responses to Stroma-directed Therapy in Mouse Models of Pancreatic Ductal Adenocarcinoma

Cao

Pickup

Clendenin

et al. 2019

Clinical Cancer Research

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Purpose: The dense stroma underlies the drug resistance of pancreatic ductal adenocarcinoma (PDA) and has motivated the development of stroma-directed drugs. Our objective is to test the concept that dynamic contrastenhanced (DCE) MRI using FDA-approved contrast media, an imaging method sensitive to the tumor microenvironment, can detect early responses to stroma-directed drug. Experimental Design: Imaging studies were performed in three mouse models exhibiting high desmoplastic reactions: the autochthonous PDA in genetically engineered mice (KPC), an orthotopic model in syngeneic mice, and a xenograft model of human PDA in athymic mice. An investigational drug, PEGPH20 (pegvorhyaluronidase alfa), which degrades hyaluronan (HA) in the stroma of PDA, was injected alone or in combination with gemcitabine. Results: At 24 hours after a single injection of PEGPH20, K trans , a DCE-MRI-derived marker that measures how fast a unit volume of contrast media is transferred from capillaries to interstitial space, increased 56% and 50% from baseline in the orthotopic and xenograft tumors, respectively, compared with a 4% and 6% decrease in vehicle groups (both P < 0.05). Similarly, after three combined treatments, K trans in KPC mice increased 54%, whereas it decreased 4% in controls treated with gemcitabine alone (P < 0.05). Consistently, after a single injection of PEGPH20, tumor HA content assessed by IHC was reduced substantially in all three models while drug delivery (measured by paclitaxel accumulation in tumor) was increased by 2.6-fold. Conclusions: These data demonstrated a DCE-MRI marker, K trans , can detect early responses to stroma-directed drug and reveal the sustained effect of combination treatment (PEGPH20þ gemcitabine).

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“…Although our results revealed a significantly lower vessel contrast in the hepatic artery for VIBE CS in comparison to VIBE STD , there was no case of insufficient arterial enhancement and no significant differences were found regarding the conspicuity of early enhancing hepatic lesions. Nevertheless, more focused studies are desirable assessing hepatic artery phase imaging in comparison to other techniques, specifically designed for data acquisition at high temporal resolution …”

Section: Discussionmentioning

confidence: 99%

“…Nevertheless, more focused studies are desirable assessing hepatic artery phase imaging in comparison to other techniques, specifically designed for data acquisition at high temporal resolution. 23,24 The high temporal resolution of VIBE CS seems also promising to allow for calculating quantitative perfusion parameters as known from computed tomography imaging. 25 This would provide additional information about perfusion characteristics of liver pathologies and thus support diagnostic reliability.…”

Section: Discussionmentioning

confidence: 99%

Self‐gated 4D‐MRI of the liver: Initial clinical results of continuous multiphase imaging of hepatic enhancement

Weiß

Notohamiprodjo

Martirosian

et al. 2017

Magnetic Resonance Imaging

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Feasibility of free-breathing dynamic contrast-enhanced MRI of the abdomen: a comparison between CAIPIRINHA-VIBE, Radial-VIBE with KWIC reconstruction and conventional VIBE

Cited by 10 publications

References 19 publications

Intraindividual Comparison between the Contrast-Enhanced Golden-Angle Radial Sparse Parallel Sequence and the Conventional Fat-Suppressed Contrast-Enhanced T1-Weighted Spin-Echo Sequence for Head and Neck MRI

Intraindividual Comparison between the Contrast-Enhanced Golden-Angle Radial Sparse Parallel Sequence and the Conventional Fat-Suppressed Contrast-Enhanced T1-Weighted Spin-Echo Sequence for Head and Neck MRI

Dynamic Contrast-enhanced MRI Detects Responses to Stroma-directed Therapy in Mouse Models of Pancreatic Ductal Adenocarcinoma

Self‐gated 4D‐MRI of the liver: Initial clinical results of continuous multiphase imaging of hepatic enhancement

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