2005
DOI: 10.1097/01.mpg.0000176181.66390.54
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Fatty Acids in Early Human Milk after Preterm and Full‐Term Delivery

Abstract: In this study, percentage contributions of arachidonic and docosahexaenoic acids as well as the those of the intermediary metabolites of essential fatty acid metabolism were all significantly higher in early human milk samples of mothers giving birth to very low birth weight preterm as compared with full-term infants.

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Cited by 67 publications
(67 citation statements)
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References 31 publications
(43 reference statements)
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“…Because blood sampling was obtained at d 4, even considering the possible differences in the LCPUFA content in milk of mothers with preterm delivery, as found in cases of severe, and not mild, prematurity (24), the amount of milk consumed by the infant during the first days of life would have just a minimal impact on his LCPUFA status, at the point to explain differences in the FA pattern. Moreover, it has already been demonstrated that the relationships between LCPUFA concentrations at birth and postnatal changes during the first 6 wks after birth are just partly dependent on the composition of the supplied milk (25).…”
Section: Discussionmentioning
confidence: 99%
“…Because blood sampling was obtained at d 4, even considering the possible differences in the LCPUFA content in milk of mothers with preterm delivery, as found in cases of severe, and not mild, prematurity (24), the amount of milk consumed by the infant during the first days of life would have just a minimal impact on his LCPUFA status, at the point to explain differences in the FA pattern. Moreover, it has already been demonstrated that the relationships between LCPUFA concentrations at birth and postnatal changes during the first 6 wks after birth are just partly dependent on the composition of the supplied milk (25).…”
Section: Discussionmentioning
confidence: 99%
“…t he amount of n-3 long-chain polyunsaturated fatty acids (LCPUFAs) in human breast milk is subject to maternal nutrition and further modified by maternal adipose tissue stores (1), gestational age and stage of lactation (2,3), and the individual's genetic constitution (variants in the FADS1/2 gene cluster) (4,5). There is an ongoing debate about whether the amount of n-3 LCPUFAs, and particularly the proportions of docosahexaenoic acid (DHA, 22:6n-3), provided to the developing infant during the breastfeeding period may result in functional differences of health outcomes in the offspring.…”
mentioning
confidence: 99%
“…Было показано, что после рождения ферментные системы недоношенных младенцев характеризуются особенно низкой способностью метаболизировать эссенциальные жирные кислоты в ДЦПНЖК [51], что стало научным обо-снованием для обогащения смесей для питания недоно-шенных детей длинноцепочечными жирными кислотами.…”
Section: влияние обеспеченности дцпнжк на развитие и функционированиеunclassified