Fatty acid profile variations of Alpine goat’s milk in response to detoxified <i>Argania spinosa</i> press cake supplementation

Lakram, Nazha; Mercha, Ikram; Moutik, Sana; Maadoudi, El Haj El; Kabbour, Rachid; Douaik, Ahmed; Naciri, Mariam

doi:10.1080/00207233.2020.1781401

Cited by 1 publication

(1 citation statement)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to the data obtained, although there was a numerical difference in the experimental groups in terms of final body weight and average daily feed intake compared to the control group, it was not statistically significant (p>0.05) (Table 2). Studies conducted with the addition of various feed additives with different antioxidant properties to the rations have reported similar results to the control group (Çiftçi et al, 2013;Sarıkaya et al, 2018;Singh and Kumar, 2018;Youssef et al, 2021;Lakram et al, 2019;Chaudhary et al, 2018). As a result of the study, it was determined that there was a similarity between the control group and the experimental groups.…”

Section: Discussionmentioning

confidence: 69%

Investigation of the Bioactivity of Escin in Hydrogen Peroxide-Induced Oxidative Stress

KÜÇÜKGÜL,

İşgör,

Önel

2023

J Hellenic Vet Med Soc

View full text Add to dashboard Cite

Escin is a triterpene saponin obtained from the horse chestnut tree Aesculus hippocastanum L. (Hippocastanaceae). The aim of this study is to investigate the bioactivity of escin against hydrogen peroxide-induced oxidative stress in quails. The study was conducted in male Japanese quails (n=10) with similar pre-experimental weights (Coturnix coturnix japonica) on average. In order to create oxidative stress in quails, hydrogen peroxide was given to drinking water ad libitum for 1 week. At the end of the period, escin was injected intraperitoneally to the quails twice, every other day. The weights of the experimental animals were measured at the beginning and the end of the experiment and compared. In addition, the 10-day live weight change rate and feed consumption rates of the experimental animals were also compared. Total antioxidant (TAC), total oxidant (TOC) and oxidative stress index (OSI) were measured colorimetrically from serum and liver homogenates of animals in the experimental groups. In addition, IL-1β translation levels from serum samples were investigated by ELISA method. According to the data obtained from the study, 10-day body weight change rates increased by 33% in the hydrogen peroxide added group compared to the control group, while an increase of 133% was observed in the escin-treated group. Besides, in serum and liver samples, it was found that escin showed strong antioxidant properties by decreasing the amount of TOC and increasing TAC levels in the group escin administered with hydrogen peroxide, compared to the group administered only with hydrogen peroxide. It was also observed that escin significantly suppressed the levels of IL-1β induced by hydrogen peroxide. As a result, escin was thought to be an alternative molecule in improving growth performance by showing significant antioxidant activity in the prevention of oxidative stress and inflammation in quails. However, multiple trials and detailed molecular analyzes are needed to obtain more detailed information on the subject.

show abstract