Fatty acid composition of cholesteryl esters in serum in boys from 16 developing and developed countries

Knuiman, J.T.; West, C.E.; Hermus, R.J.J.; Hautvast, J.G.A.J.

doi:10.1016/0021-9150(80)90068-4

Cited by 23 publications

(5 citation statements)

References 16 publications

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“…The study of Knuiman et al (18) on the C E fatty acid composition in 7 to 8-year-old boys from 16 countries included 11 samples from urban and rural areas in Finland: the percentages of CE-18:2 were 55 and 50 070 in the urban and rural areas of Finland, respectively, while the mean values in nine other European countries ranged from 45 to 58 '70. So the proportion of polyunsaturated fatty acids in the sera of Finnish children and adolescents does not appreciably differ from that in other western populations.…”

Section: Discussionmentioning

confidence: 99%

Atherosclerosis precursors in Finnish children and adolescents. V. Fatty acid composition of serum cholesteryl esters: regional differences in Finland

et al. 1985

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ABSTRACT. Fatty acid compositions of serum cholesteryl esters (CE) were analysed with gas chromatography from a total of 1,348 Finnish children. The study was a part of a comprehensive survey of atherosclerosis precursors among children, and included 3‐, 6‐, 9‐, 12‐, 1.5, and 18‐year‐old children and adolescents from five urban and twelve rural communities in Finland. In all age groups and both sexes, the mean percentages of linoleate (CE‐18:2) were lower and those of saturated and monounsaturated fatty acids higher in eastern rural areas than elsewhere. Eastern rural children also had significantly higher proportions of ω3 polyunsaturated fatty acids in their serum CE's. The percentage of serum CE‐18:2 parellels the PIS values obtained by a dietary survey from the same populations. The reason for higher percentages of the ω3 fatty acids in rural communities cannot be explained by diet, and remains unclear.

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Section: Discussionmentioning

confidence: 99%

Atherosclerosis precursors in Finnish children and adolescents. V. Fatty acid composition of serum cholesteryl esters: regional differences in Finland

et al. 1985

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“…Besides a marker of adherence, we did not anticipate the contribution that other factors make in determining CE content. The CE fatty acid content varies within a relatively narrow range, 44 does not predict serum cholesterol levels, 45 and may be subject to genetic regulation. In a study of 69 twin pairs and their brothers, monozygotic twins had smaller differences in CE fatty acid content com-pared with dizygotic twins and brothers.…”

Section: Commentmentioning

confidence: 99%

Individual Cholesterol Variation in Response to a Margarine- or Butter-Based Diet

Denke¹,

Adams‐Huet²,

Nguyen³

2000

JAMA

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“…The pattern of fatty acids in the blood and adipose tissue is used as a biomarker to assess differences in fatty acid dietary intake between individuals or populations (Knuiman et al, 1980;Katan et al, 1991;Nikkari et al, 1995;Zock et al, 1997). Fish is the primary source of the major o-3 polyunsaturated fatty acids (PUFA), eicosapentaenoic acid (EPA; C20:5, o-3) and docosahexaenoic acid (DHA; C22:6, o-3).…”

Section: Introductionmentioning

confidence: 99%

Very-long-chain ω-3 fatty acids as markers for habitual fish intake in a population consuming mainly lean fish: the EPIC cohort of Gipuzkoa

Amiano

Dorronsoro

et al. 2001

Eur J Clin Nutr

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Objective: To assess the relationship between habitual fish intake and fatty acid levels in serum as well as in the LDL fractions of serum phospholipids and cholesteryl esters. Design: Cross-sectional study. Setting: Cohort of Gipuzkoa (Basque Country, northern Spain) included in the European Prospective Investigation into Cancer and Nutrition (EPIC) project. Subjects: Random sample of 120 healthy volunteers of both sexes aged 35 -65 y, divided into various consumption groups according to daily fish intake. Methods: Data on habitual intake over the previous year was collected by trained interviewers by means of a computerized questionnaire based on the diet history method. Fasting venous blood samples were drawn and fatty acids were measured by gas-liquid chromatography. Results: Lean fish accounted for 78% of all fish consumption in the highest consumption group ( > 115 g=day) and for 60% in the lowest ( < 31 g=day). The mean concentrations of o-3 polyunsaturated fatty acids (PUFA), eicosapentaenoic acid (EPA, C20:5, o-3), and docosahexaenoic acid (DHA, C22:6, o-3) in serum and in the LDL fractions of serum phospholipids and cholesteryl esters increased significantly from the lowest to the highest fish consumption categories. Fish intake showed a statistically significant relationship with o-3 PUFA, EPA and DHA in serum and in the LDL fractions of serum phospholipids and cholesteryl esters both in the simple linear regression analysis and in a multiple regression model adjusted by age, body mass index (BMI) and vegetable intake. Conclusions: Habitual fish intake is reflected in the content of EPA and DHA in serum and in the LDL phospholipid and cholesteryl esters fractions. The concentrations of very-long-chain o-3 fatty acids are useful biomarkers for dietary fish intake, mainly lean fish. Sponsorship: Europe Against Cancer Programme of the European Union (agreement SOC 97 200302 05F02); 'Fondo de Investigaciones Sanitarias', Spanish Ministry of Health (FIS grant 99=0024-05); Government of the Basque Country; and 'Fundación Científica de la Asociación Española contra el Cáncer'. Descriptors: fish intake; fish oil; n-3 fatty acids; biological markers; eicosapentaenoic acid; docosahexaenoic acid

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Fatty acid composition of cholesteryl esters in serum in boys from 16 developing and developed countries

Cited by 23 publications

References 16 publications

Atherosclerosis precursors in Finnish children and adolescents. V. Fatty acid composition of serum cholesteryl esters: regional differences in Finland

Atherosclerosis precursors in Finnish children and adolescents. V. Fatty acid composition of serum cholesteryl esters: regional differences in Finland

Individual Cholesterol Variation in Response to a Margarine- or Butter-Based Diet

Very-long-chain ω-3 fatty acids as markers for habitual fish intake in a population consuming mainly lean fish: the EPIC cohort of Gipuzkoa

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