Fate and bioavailability of sulfamethazine in freshwater ecosystems

Henderson, Keri L. D.; Coats, Joel R.

doi:10.1021/bk-2009-1018.ch009

Cited by 9 publications

(17 citation statements)

References 24 publications

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“…Our results and those of others (9,34,36,37) show that erythromycin and other antibiotics partition from the overlying water into stream and pond sediments. We examined the dissipation of erythromycin residues in sediment that had been previously aged for 1, 3 or 8 weeks.…”

Section: Aged Residues Study: Sedimentsupporting

confidence: 85%

Fate of Erythromycin in Sediment-Containing Surface Water Microcosms: How Does Aged Erythromycin in Sediment Influence Bioavailability?

Jessick

Coats

2013

ACS Symposium Series

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The detection of antibiotics in water and sediment systems is of concern due to the potential adverse effects which could be associated with their environmental fate. The central aim of this study was to evaluate the fate of erythromycin in microcosms consisting of pond water and submerged pond sediment. The first study examined the dissipation of erythromycin from spiked water and total recovery of [14C]-erythromycin from water and sediment within microcosms ranged between 90.1% and 48% throughout the 63-day study. Erythromycin was reduced in surface water of sediment-containing systems by day 7, which corresponded to an increase of eryrthromycin detected in sediment. In the second study the availability of aged erythromycin was evaluated by incubating sediment with and without a manure amendment with [14C]-erythromycin for 0, 1, 3, or 8 weeks; followed by assessing movement and availability of erythromycin in sediment microcosms after 1, 3, 7, and 14 days. Results indicated differences in residues from aged sediment, with and without manure additions, in extractable residues at day 7 and 14. The addition of manure resulted in greater extractable erythromycin from aged sediments than from sediments without manure. There was a greater release of erythromycin to the water overlying the manure-treated sediments with fresh and 1 week aged sediment than the unamended sediment after 1 and 2 weeks. The results from this experiment demonstrate the ability of manure to influence the fate of erythromycin in environmental matrices. RightsWorks produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted. The detection of antibiotics in water and sediment systems is of concern due to the potential adverse effects which could be associated with their environmental fate. The central aim of this study was to evaluate the fate of erythromycin in microcosms consisting of pond water and submerged pond sediment. The first study examined the dissipation of erythromycin from spiked water and total recovery of [ 14 C]-erythromycin from water and sediment within microcosms ranged between 90.1% and 48% throughout the 63-day study. Erythromycin was reduced in surface water of sediment-containing systems by day 7, which corresponded to an increase of eryrthromycin detected in sediment. In the second study the availability of aged erythromycin was evaluated by incubating sediment with and without a manure amendment with [ 14 C]-erythromycin for 0, 1, 3, or 8 weeks; followed by assessing movement and availability of erythromycin in sediment microcosms after 1, 3, 7, and 14 days. Results indicated differences in residues from aged sediment, with and without manure additions, in extractable residues at day 7 and 14. The addition of manure resulted in greater extractable erythromycin from aged sediments than from sediments without manure. There was a greater release of erythromycin to the water overlying the manure-treated

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Section: Aged Residues Study: Sedimentsupporting

confidence: 85%

Fate of Erythromycin in Sediment-Containing Surface Water Microcosms: How Does Aged Erythromycin in Sediment Influence Bioavailability?

Jessick

Coats

2013

ACS Symposium Series

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“…Treatment preparation was briefly described by Henderson et al (2009). 22 The fate of sulfamethazine was examined in four pond water systems: pond water and sediment (PWS), autoclaved pond water and sediment, pond water without sediment (PW), and pond water and sediment with SMZ added with dilute manure (PWS +M) with four replications of each. Microcosms were constructed by adding 73 g of sediment (50 g dry wt) into wide-mouth pint jars (Ball Corp., Broomfield, CO), and topped with 177 mL of pond water to equal 200 mL of water per jar.…”

Section: ■ Experimental Materials and Methodsmentioning

confidence: 99%

Sorption and Photodegradation Processes Govern Distribution and Fate of Sulfamethazine in Freshwater–Sediment Microcosms

Carstens

Gross

Moorman

et al. 2013

Environ. Sci. Technol.

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The antibiotic sulfamethazine can be transported from manured fields to surface water bodies. We investigated the degradation and fate of sulfamethazine in pond water using (14)C-phenyl-sulfamethazine in small pond water microcosms containing intact sediment and pond water. We found a 2.7-day half-life in pond water and 4.2-day half-life when sulfamethazine was added to the water (5 mg L(-1) initial concentration) with swine manure diluted to simulate runoff. Sulfamethazine dissipated exponentially from the water column, with the majority of loss occurring via movement into the sediment phase. Extractable sulfamethazine in sediment accounted for 1.9-6.1% of the applied antibiotic within 14 days and then declined thereafter. Sulfamethazine was transformed mainly into nonextractable sediment-bound residue (40-60% of applied radioactivity) and smaller amounts of photoproducts. Biodegradation, as indicated by metabolite formation and (14)CO2 evolution, was less significant than photodegradation. Two photoproducts accounted for 15-30% of radioactivity in the water column at the end of the 63-day study; the photoproducts were the major degradates in the aqueous and sediment phases. Other unidentified metabolites individually accounted for <7% of radioactivity in the water or sediment. Less than 3% of applied radioactivity was mineralized to (14)CO2. Manure input significantly increased sorption and binding of sulfamethazine residues to the sediment. These results show concurrent processes of photodegradation and sorption to sediment control aqueous concentrations and establish that sediment is a sink for sulfamethazine and sulfamethazine-related residues. Accumulation of the photoproducts and sulfamethazine in sediment may have important implications for benthic organisms.

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“…Thus, the hydrolysis of these antibiotics is not to be expected in surface water, groundwater or anaerobic lagoons. The recent study of Henderson et al (2009) has confirmed that in respect to the bioconcentration factor, sulfamethazine belongs to the class of persistent hydrophobic contaminants. Thus, sediment is a potential sink for this contaminant.…”

Section: Photodegradationmentioning

confidence: 86%