Fatal Henoch-Schonlein Purpura in an adult related to bowel perforation: Report and review of the literature

Miniter, Una; Bae‐Harboe, Yoon‐Soo Cindy; Powers, Jennifer G.; Campbell, Shannon; Goldberg, Lynne J.

doi:10.5070/d32f50n7g6

Cited by 12 publications

(3 citation statements)

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“…In 40–50% of the patients, the mesenteric circulation is involved [ 26 ]. Rarely (3–5%) patients may experience serious complications, including bowel infarct, perforation [ 84 ], obstruction, or irreducible intussusception [ 85 ]. Intestinal ischemia can even be the initial manifestation of the disease (29).…”

Section: Small-vessel Vasculitismentioning

confidence: 99%

Imaging of intestinal vasculitis focusing on MR and CT enterography: a two-way street between radiologic findings and clinical data

et al. 2022

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Diagnosis of intestinal vasculitis is often challenging due to the non-specific clinical and imaging findings. Vasculitides with gastrointestinal (GI) manifestations are rare, but their diagnosis holds immense significance as late or missed recognition can result in high mortality rates. Given the resemblance of radiologic findings with some other entities, GI vasculitis is often overlooked on small bowel studies done using computed tomography/magnetic resonance enterography (CTE/MRE). Hereon, we reviewed radiologic findings of vasculitis with gastrointestinal involvement on CTE and MRE. The variety of findings on MRE/CTE depend upon the size of the involved vessels. Signs of intestinal ischemia, e.g., mural thickening, submucosal edema, mural hyperenhancement, and restricted diffusion on diffusion-weighted imaging, are common in intestinal vasculitis. Involvement of the abdominal aorta and the major visceral arteries is presented as concentric mural thickening, transmural calcification, luminal stenosis, occlusion, aneurysmal changes, and collateral vessels. Such findings can be observed particularly in large- and medium-vessel vasculitis. The presence of extra-intestinal findings, including within the liver, kidneys, or spleen in the form of focal areas of infarction or heterogeneous enhancement due to microvascular involvement, can be another radiologic clue in diagnosis of vasculitis. The link between the clinical/laboratory findings and MRE/CTE abnormalities needs to be corresponded when it comes to the diagnosis of intestinal vasculitis.

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Section: Small-vessel Vasculitismentioning

confidence: 99%

Imaging of intestinal vasculitis focusing on MR and CT enterography: a two-way street between radiologic findings and clinical data

et al. 2022

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“…Появление множественных геморрагий и эрозий СО ЖКТ может вызывать серьезное кровотечение, которое отмечается примерно у 1/3 больных и проявляется гематемезисом и меленой. Эндоскопическая картина поражения ЖКТ неспецифична: при эзофагогастродуоденоскопии (ЭГДС) и фиброколоноскопии (ФКС) выявляются множественные геморрагии, эрозии, иногда язвы, преимущественно локализованные в области ДПК и подвздошной кишки [2,[25][26][27].…”

Section: системные васкулитыunclassified

“…Как было отмечено выше, серьезные затруднения в дифференциальном диагнозе могут возникнуть, если развитию ПШГ предшествует кишечная инфекция: в этом случае требуется большое внимание для разделения клиники инфекционного и ревматического заболевания. Важную помощь в диагностике IgA-васкулита может оказать сочетание абдоминальных симптомов и поражения почек (варь ирующего от мочевого синдрома до гломерулонефрита) -второй по частоте органной патологии, возникающей при ПШГ [2,[25][26][27].…”

Section: системные васкулитыunclassified

Manifestations of the gastrointestinal tract in systemic rheumatic diseases: A narrative review

Moroz¹,

Попкова²,

Karateev³

2022

Naučno-praktičeskaâ revmatologiâ

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Gastrointestinal disorders are important place among the visceral manifestations of systemic autoimmune and immunoinflammatory rheumatic diseases (RD). Pathology of the esophagus, stomach, small and large intestine can vary from moderate functional disorders to the development of severe chronic inflammation with metaplasia and dysplasia of the mucous membrane, the formation of multiple erosions, hemorrhages and deep ulcers. Complications of gastrointestinal pathology in RD, such as bleeding, perforations and strictures, can cause death. This review examines the main clinical manifestations, possibilities of diagnosis and treatment of gastrointestinal lesions in systemic scleroderma, idiopathic inflammatory myopathies, systemic vasculitis, Sjogren’s syndrome and disease, as well as systemic lupus erythematosus.

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Small bowel ischemia as an unusual complication of Henoch‐Schönlein purpura in an adult: A case report

Yen

Hsu

et al. 2020

Adv in Digestive Medicine

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Fatal Henoch-Schonlein Purpura in an adult related to bowel perforation: Report and review of the literature

Cited by 12 publications

References 0 publications

Imaging of intestinal vasculitis focusing on MR and CT enterography: a two-way street between radiologic findings and clinical data

Imaging of intestinal vasculitis focusing on MR and CT enterography: a two-way street between radiologic findings and clinical data

Manifestations of the gastrointestinal tract in systemic rheumatic diseases: A narrative review

Small bowel ischemia as an unusual complication of Henoch‐Schönlein purpura in an adult: A case report

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