Fatal cerebral venous sinus thrombosis as major complication of metastatic cervical mass: computed tomography and magnetic resonance findings

López-Peláez, María F.; Millán, José María; Vergas, Joaquín De

doi:10.1258/0022215001903979

Cited by 12 publications

(11 citation statements)

References 13 publications

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“…5 Furthermore, CVST accompanied by squamous cell metastatic cervical mass, non-Hodgkin's lymphoma, and cerebral metastases of a colorectal cancer have been described. [8][9][10] The CVST infrequently presents as a paraneoplastic syndrome. 6 The CVST may accompany brain tumors such as brain glioma, and meningioma; it is noticeable that in brain tumors, the direct invasion of sinuses by tumors (especially in meningioma) provokes the development of CVST.…”

Section: Discussionmentioning

confidence: 99%

Superior sagittal sinus and transverse sagittal sinus thrombus secondary to occult meningioma

et al. 2017

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The superior sagittal sinus is the largest of the venous sinuses. It receives blood from the frontal, parietal, and occipital superior cerebral veins and the diploic veins, which communicate with the meningeal veins. The superior sagittal sinus drains into the transverse sinuses. Central nervous system tumors like meningioma, glomus tumor, and meduloblastoma, often directly compress the veins and sinuses of the brain. Major sites of the occlusion include superior sagittal sinus (SSS) and transverse sinus. Initial days cerebral venous sinus thrombosis (CVST) was diagnosed only on autopsy. Since the advent of modern investigative modalities like magnetic resonance Imaging (MRI), Computerised Tomography Angiography (CTA) and Magnetic Resonance Venography (MRV), more and more cases are being diagnosed confidently.

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Section: Discussionmentioning

confidence: 99%

Superior sagittal sinus and transverse sagittal sinus thrombus secondary to occult meningioma

et al. 2017

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“…Potential mechanisms for an association of cancer with cerebral venous thrombosis (CVT) include direct tumor compression, tumor invasion of cerebral sinuses, the hypercoagulable state associated with cancer, or the chemotherapeutic side effects [3–5]. Cerebral venous thrombosis has been reported to be associated with various cancers like squamous cell cervical cancer [6], non-Hodgkin's lymphoma [7], and breast cancer [8]. Cerebral sinus venous thrombosis associated with chemotherapy has so far been described in a patient with colon cancer treated with FOLFIRI/bevacizumab [9], in a patient with a brain tumor treated with temozolomide, focal brain radiotherapy plus bevacizumab [10], in an adolescent with Ewing sarcoma treated with cisplatin, ifosfamide, adriamycin, and vincristine [11], and in two patients of nonseminomatous germ cell tumor treated with cisplatin, bleomycin, and etoposide [12].…”

Section: Discussionmentioning

confidence: 99%

Cerebral Venous Thrombosis: A Mimic of Brain Metastases in Colorectal Cancer Associated with a Better Prognosis

Iqbal

Sharma

2013

Case Reports in Oncological Medicine

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Malignancy is known to be one of the predisposing factors of cerebral venous thrombosis (CVT) due to its hypercoagulable state. CVT is a rare disorder which can lead to frequent misdiagnoses of brain metastases in such cases. We report here the case of a 35-year-old female with metastatic colon adenocarcinoma presenting with sudden neurological symptoms. Brain MRI and magnetic resonance venography confirmed the presence of CVT. She was treated with low molecular weight heparin followed by warfarin. She recovered and is doing well on warfarin after 5 months of diagnosis of CVT. CVT should be strongly suspected as a cause of neurological dysfunction in any case of disseminated malignancy including colon adenocarcinoma. Rapid diagnosis and initiation of therapy should be considered because of its favourable outcome.

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“…Different kinds of malignancies have been reported with CVST (17,18). It was supposed that coagulation disorders, direct effect of tumor, therapeutic agents might be the reason (17).…”

Section: Discussionmentioning

confidence: 99%

Cerebral venous sinus thrombosis: gender differences in ten years experience

Özcan¹,

Meral²,

Özben³

et al. 2013

Dusunen Adam

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Cerebral venous sinus thrombosis: gender differences in ten years experienceObjective: Cerebral venous sinus thrombosis (CVST) is an uncommon subtype of stroke. CVST is much more common in women than men with a ratio of three to one. This women preponderance is attributed to gender-specific risk factors (GSRF). In many patients, symptoms develop over days or weeks. In some patients, clinical presentations are nonspesific. Patients and Methods: We reviewed the records of patients with CVST treated at Neurology department of Haseki Training and Research Hospital between 2001-2011, which diagnoses were confirmed with cranial magnetic resonance imaging (MRI) and magnetic resonance venography (MRV). Thirty-four patients were included the study. Women/men ratio was 3.25/1. We analyzed the demographic features, comorbid conditions, clinical presentation, neuroradiological findings. Results: Thirty-four patients were included the study. Headache was present in all patients and it was present as isolated in 47.1% (n=16) of the patients. In 52.9% (n=18) of the patients onset of the symptoms were subacute, 29.4% (n=10) chronic, 17.6 (n=6) acute. Of all patients, 76.5% (n=26) were women. Transverse sinus was the mostly affected sinus as either isolated or with the other CSVT in both groups (in 20 women and 8 men). The most common presentation symptom (43.78%) in women was headache whereas; it was intracranial hypertension (34.78%) in men. Half of our women patients with GRSF; 7 (26.92%) women were oral contraceptives user and 5 (15.38%) women were in pregnancy or puerperium period. Conclusion: We have found differences between women and men in the presentation and risk factors. Key words: Gender, risk factors, sinus thrombosis ÖZET Serebral sinus ven trombozu: On yıllık tecrübede cinsiyet farklılıklarıAmaç: Serebral sinus ven trombozu (SSVT) inmenin nadir nedenlerindendir. SSVT kadınlarda erkekleklere göre üçe bir oranında daha sık görülür. Bu kadın baskınlığı cinsiyete özgü rik faktörlerine bağlanmaktadır. Hastaların çoğunda semptomlar günler veya haftalar içinde yerleşmektedir. Bazı hastalarda klinik görünüm nonspesifik olmaktadır. Yöntem: Haseki Eğitim ve Araştırma Hastanesinde 2001-2011 yılları arasında cranial MR ve MR venografi ile tanısı doğrulanarak SSVT tedavisi almış hasta kayıtlarını inceledik. Çalışmaya otuz dört hasta dahil edildi. Kadın/ erkek oranı 3.25/1 idi. Hastaların demografik özelliklerini, komorbid durumlarını, klinik görünümlerini, nöroradyolajik bulgularını inceledik. Bulgular: Çalışmaya otuz dört hasta dahil edildi. Başağrısı hastaların %47.1'inde (n=16) izole olmak üzere tüm hastalarda mevcuttu. Semptomların başlangıcı hastaların %52.9'unda (n=18) subakut, %29.4'ünde (n=10) kronik, %17.6'sında (n=6) akut idi. Tüm hastaların %76.5'i (n=26) kadındı. Her iki cinsiyette de en sık etkilenen sinus transvers sinus olarak saptandı (20 kadın ve 8 erkek). Başvurudaki en sık semptom kadınlarda başağrısı (%43.78) iken, erkeklerde intracranial hipertansiyon (%34.78) idi. Cinsiyete özgü risk faktörü sap...

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Fatal cerebral venous sinus thrombosis as major complication of metastatic cervical mass: computed tomography and magnetic resonance findings

Cited by 12 publications

References 13 publications

Superior sagittal sinus and transverse sagittal sinus thrombus secondary to occult meningioma

Superior sagittal sinus and transverse sagittal sinus thrombus secondary to occult meningioma

Cerebral Venous Thrombosis: A Mimic of Brain Metastases in Colorectal Cancer Associated with a Better Prognosis

Cerebral venous sinus thrombosis: gender differences in ten years experience

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