Fat Absorption in Newborns: Commentary on the article by Rings et al. on page 57

Clandinin, Michael T.

doi:10.1203/00006450-200201000-00003

Cited by 4 publications

References 2 publications

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High‐DHA eggs: Feasibility as a means to enhance circulating DHA in mother and infant

Smuts

Borod

Peeples

et al. 2003

Lipids

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Dietary DHA enhances infant attention and visual development. Because the DHA content of red blood cells and plasma lipids varies approximately threefold in pregnancy, maternal DHA status may influence subsequent infant function. It would be feasible to study the effects of higher maternal DHA intake on infant development if dietary intake of DHA could be increased by a reliable means. This study was designed to determine whether women provided with one dozen high-DHA hen eggs (135 mg DHA/egg) would consume the eggs and have higher blood DHA levels than women consuming ordinary eggs (18 mg DHA/egg). The study was a randomized, double-masked comparison of the effect of eggs with different concentrations of DHA on intake and blood lipid DHA content of women and their infants. A third nonrandomized group ate few eggs. In this study, DHA intake reported from eggs was eightfold higher in the high-DHA egg group compared to the ordinary egg group. Including all groups, DHA intake ranged from 0 to 284 mg/d. In this intake range, maternal blood lipid DHA content at enrollment best predicted DHA content at delivery, accounting for 36.5 and 51.7% of the variance in ordinary and high-DHA egg intake groups, respectively. The high-DHA vs. ordinary egg groups had similar maternal and cord blood lipid DHA, but there was a positive relationship between maternal plasma phospholipid DHA and daily DHA intake from eggs controlled for study duration (r = 0.278, P = 0.048). DHA intake and birth weight were also correlated (r = 0.299, P = 0.041). High-DHA eggs were well accepted and increased DHA intake. Other benefits of DHA intake during pregnancy were also suggested.

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High‐DHA eggs: Feasibility as a means to enhance circulating DHA in mother and infant

Smuts

Borod

Peeples

et al. 2003

Lipids

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The Role of Essential Fatty Acids in Development

2005

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The presence of docosahexaenoic acid (DHA) and arachidonic acid (ARA) in human milk but not in infant formula, coupled with lower plasma and brain lipid contents of DHA in formula-fed than in breast-fed infants and reports of higher IQ in individuals who were breast-fed versus formula-fed as infants, suggest that exogenous DHA (and ARA) may be essential for optimal development. Thus, since 1990, several studies have examined the impact of formulas containing DHA or DHA plus ARA on visual function and neurodevelopmental outcome. Some of these studies have shown benefits but others have not. These results leave largely unanswered the question of whether these fatty acids are beneficial for either the term or preterm infant. However, evidence that preterm infants might benefit is somewhat more convincing than that for term infants. Despite the limited evidence for efficacy, formulas supplemented with DHA and ARA are now available and appear to be safe.

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Nutrition Support for the Critically Ill Neonate

Bhatia¹,

Nagy²

2005

Nutrition Support for the Critically Ill Patient

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Fat Absorption in Newborns: Commentary on the article by Rings et al. on page 57

Cited by 4 publications

References 2 publications

High‐DHA eggs: Feasibility as a means to enhance circulating DHA in mother and infant

High‐DHA eggs: Feasibility as a means to enhance circulating DHA in mother and infant

The Role of Essential Fatty Acids in Development

Nutrition Support for the Critically Ill Neonate

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