Fasting Plasma Glucose Mediates the Prospective Effect of Maternal Metal Level on Birth Outcomes: A Retrospective and Longitudinal Population-Based Cohort Study

Zhou, Zixing; Yu, Dandan; Chen, Gengdong; Li, Pengsheng; Wang, Limin; Yang, Jie; Rao, Jiaming; Lin, Dongxin; Fan, Dazhi; Wang, Haiyan; Gou, Xiaoyan; Guo, Xiaoling; Suo, Dongmei; Huang, Fang; Liu, Zheng­ping

doi:10.3389/fendo.2021.763693

Cited by 2 publications

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References 51 publications

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“…Additionally, zinc has multiple roles in brain growth, differentiation, and repair (48). One prospective study of 7,644 pregnant women in Foshan, China also showed that maternal serum zinc levels at 24 GW were positively correlated with neonatal HC (49). Notably, the level of zinc in shellfish is much higher than that in fish and shrimp, which may lead to their different effects on HC (28).…”

Section: Discussionmentioning

confidence: 99%

Associations of maternal dietary patterns during pregnancy and fetal intrauterine development

Qin

Lü

et al. 2022

Front. Nutr.

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Dietary pattern is excellent in reflecting an individual's eating conditions. Longitudinal data on fetal growth can reflect the process of intrauterine growth. We aimed to evaluate the associations between maternal dietary patterns and intrauterine parameters in middle and late pregnancy. The present study was conducted within Jiangsu Birth Cohort (JBC) study. Dietary information was assessed with a food frequency questionnaire (FFQ) in the second and third trimester of gestation. B-ultrasound scans were performed to obtain fetal intrauterine parameters, including head circumference (HC), femur length (FL), abdominal circumference (AC), and estimated fetal weight (EFW). Exploratory factor analysis was used to extract dietary patterns. Multiple linear regression and linear mixed-e ects model (LMM) were used to investigate the association between maternal dietary patterns and fetal growth. A total of , pregnant women were eligible for the study. We observed inverse associations of maternal "Vegetables and fish" and "Snack and less eggs" patterns during mid-pregnancy with fetal HC Z-score, respectively ("Vegetables and fish": β = − . , % CI − . , − . ; "Snack and less eggs": β = − . , % CI − . , − . ). On the contrary, "Animal internal organs, thallophyte and shellfish" pattern in the second trimester was associated with increased HC Z-scores (β = . , % CI . , . ). Consistently, score increase in "Vegetables and fish" pattern in the third trimester was inversely associated with the Z-scores of HC (β = − . , % CI − . , − . ), while "Meat and less nuts" pattern was positively correlated with the Z-scores of HC (β = . , % CI . , . ). As compared to the fetus whose mothers at the lowest tertile of "Snack and less eggs" pattern in both trimesters, those whose mothers at the highest tertile demonstrated . fold (RR = . , % CI . -. ) increased risk of small HC for gestational age (GA). No correlation was observed between maternal Frontiers in Nutrition frontiersin.org Qin et al. . /fnut. .dietary patterns and other intrauterine parameters. Our results suggested the e ects of maternal dietary patterns on fetal growth, particularly HC. These findings highlighted the adverse impact of unhealthy dietary pattern on fetal growth, might provide evidence for strategies to prevent intrauterine dysplasia and dietary guidelines during pregnancy.

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Section: Discussionmentioning

confidence: 99%