Fast Local Regulations of Muscle pO2-Fields in Patients Suffering from Cirrhosis of the Liver

Fleckenstein, W.; Heinrich, R.; Grauer, W.; Schomerus, H.; Dölle, W; Weiß, Ch.

doi:10.1007/978-1-4684-4895-5_67

Cited by 8 publications

(2 citation statements)

References 4 publications

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“…Los sensores de oximetría tisular no fueron ideados inicialmente para monitorizar el parénquima encefálico 23,25 . Contrastada y validada la información que ofrecían este tipo de sensores, su aplicación se dirigió inicialmente a la monitorización de órganos e injertos trasplantados, con el objetivo de evaluar su viabilidad.…”

Section: Origen De Los Sensores De Oximetría Tisular Sistemas Disponunclassified

Actualizaciones en los métodos de monitorización cerebral regional en los pacientes neurocríticos: presión tisular de oxígeno, microdiálisis cerebral y técnicas de espectroscopía por infrarrojos

et al. 2005

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The long term outcome of head-injured patients depends not only on the primary brain lesions but also to a large extent on the secondary lesions. The diagnosis of many secondary lesions, and specially that of brain ischemia, is based on simultaneous monitoring of several intracranial and systemic variables. Continuous intracranial pressure (ICP) monitoring is currently considered indispensable in the management of all patients with a severe head injury and intracranial lesions. However, the information provided by this technique is insufficient to diagnose some of the complex physiopathological processes that characterize traumatic brain lesions. Consequently, the use of methods to estimate cerebral blood flow such as transcranial Doppler and jugular oximetry to complement ICP monitoring is becoming increasingly widespread. Nevertheless, determining the effect of tissue lesions and therapeutic measures on cerebral metabolism currently requires direct access to the brain parenchyma at the bedside. In this review we focus on three methods of regional cerebral monitoring: oxygen tissue pressure (PtiO(2)) monitoring, microdialysis and near-infrared spectroscopy. The bases of each method and reference values for the variables analyzed will be discussed. We also make a series of recommendations on how results should be interpreted in light of current knowledge.

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Section: Origen De Los Sensores De Oximetría Tisular Sistemas Disponunclassified

Actualizaciones en los métodos de monitorización cerebral regional en los pacientes neurocríticos: presión tisular de oxígeno, microdiálisis cerebral y técnicas de espectroscopía por infrarrojos

et al. 2005

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show abstract

Section: Origen De Los Sensores De Oximetría Tisular Sistemas Disponunclassified

Actualizaciones en los métodos de monitorización cerebral regional en los pacientes neurocríticos: presión tisular de oxígeno, microdiálisis cerebral y técnicas de espectroscopía por infrarrojos

et al. 2005

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PALABRAS CLAVE: Traumatismos craneoencefálicos. Metabolismo cerebral. Oxigenación tisular. Microdiálisis. Espectroscopía por infrarrojos. Recent advances in regional cerebral monitoring in the neurocritical patient: brain tissue oxygen pressure monitoring, cerebral microdialysis and near-infrared spectroscopy Summary The long term outcome of head-injured patients depends not only on the primary brain lesions but also to a large extent on the secondary lesions. The diagnosis of many secondary lesions, and specially that of brain ischemia, is based on simultaneous monitoring of several intracranial and systemic variables. Continuous intracranial pressure (ICP) monitoring is currently considered indispensable in the management of all patients with a severe head injury and intracranial lesions. However, the information provided by this technique is insufficient to diagnose some of the complex physiopathological processes that characterize traumatic brain lesions. Consequently, the use of methods to estimate cerebral blood flow such as transcranial Doppler and jugular oximetry to complement ICP monitoring is becoming increasingly widespread. Nevertheless, determining the effect of tissue lesions and therapeutic measures on cerebral metabolism currently requires direct access to the brain parenchyma at the bedside. In this review we focus on three methods of regional cerebral monitoring: oxygen tissue pressure (PtiO 2) monitoring, microdialysis and near-infrared spectroscopy. The bases of each method and reference values for the varia

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In vivo oximetry using a nitroxide‐liposome system

Glockner

Chan

Swartz

1991

Magnetic Resonance in Med

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Liposomes containing the deuterated, charged, aqueous soluble nitroxide 4-trimethyl-ammonium-2,2,6,6-tetramethylpiperidine-d16-1-oxyl (d-Cat1) were used as probes to measure oxygen concentrations in vivo. Following intramuscular or intraperitoneal injection of the liposome suspension. ICR mice were placed over the surface probe of a low frequency (1.1 GHz) electron paramagnetic resonance (EPR) spectrometer. The linewidth of the deuterated nitroxide is sensitive to changes in the dissolved oxygen concentration: this parameter was calibrated separately so that linewidths measured in the injected mice could be converted into oxygen tensions. This technique detected substantial changes in pO2 as the oxygen content of the breathing gas was changed from 21 to 85 to 0%. Intravenous injection of the liposomes also is possible, and the liposomes accumulate in the liver and spleen, where detectable, oxygen-sensitive EPR signals can be measured.

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Fast Local Regulations of Muscle pO2-Fields in Patients Suffering from Cirrhosis of the Liver

Cited by 8 publications

References 4 publications

Actualizaciones en los métodos de monitorización cerebral regional en los pacientes neurocríticos: presión tisular de oxígeno, microdiálisis cerebral y técnicas de espectroscopía por infrarrojos

Actualizaciones en los métodos de monitorización cerebral regional en los pacientes neurocríticos: presión tisular de oxígeno, microdiálisis cerebral y técnicas de espectroscopía por infrarrojos

Actualizaciones en los métodos de monitorización cerebral regional en los pacientes neurocríticos: presión tisular de oxígeno, microdiálisis cerebral y técnicas de espectroscopía por infrarrojos

In vivo oximetry using a nitroxide‐liposome system

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