Fast and Efficient Synthesis of Mono-(6-<i>p</i>-toluenesulfonyl)-<i>β</i>-cyclodextrin via Ultrasound Assisted Method

Abstract

The mono-(6-p-toluenesulfonyl)-β-cyclodextrin was firstly synthesized fast and efficiently by adopting ultrasound assisted method in alkaline water solution. The reaction time was only 40 min but with the yield of 31.1% under ultrasound condition. Compared with the conventional synthetic methods, the proposed novel method could shorten the reaction time and improve the yield. It is a simple, rapid and efficient method.