Famotidine vs. omeprazole: a prospective randomized multicentre trial to determine efficacy in non‐erosive gastro‐oesophageal reflux disease

Fujiwara, Yasuhiro; Higuchi, Kazuhide; Nebiki, Hiroko; Chono, Shinji; Uno, H; Kitada, K.; Satoh, Hiroshi; Nakagawa, Kenichiro; Kobayashi, Kanao; Tominaga, Kazunari; Watanabe, Toshio; Oshitani, Nobuhide; Arakawa, Tetsuo

doi:10.1111/j.1365-2036.2005.02468.x

Cited by 34 publications

(40 citation statements)

References 43 publications

(79 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This instrument is an abdominal symptom-related QOL scale similar to the GSRS (4, 10); it is composed of 5 symptom domains for determining various abdominal symptom-and domain-specific QOL impairments. GSRS has been widely used to measure abdominal symptom-specific QOL impairments and is reported to clearly show the QOL changes in response to treatment in Japanese patients with abdominal symptoms (11,12). However, in contrast to the GSRS and other general QOL scales, the Izumo scale was designed to detect QOL changes caused by abdominal symptoms frequently noted by Japanese patients (13)(14)(15).…”

Section: Discussionmentioning

confidence: 99%

Abdominal Symptom-related QOL in Individuals Visiting an Outpatient Clinic and those Attending an Annual Health Check

et al. 2011

View full text Add to dashboard Cite

Objective Quality of life (QOL) impairment of patients who visit an outpatient clinic for abdominal symptoms has not been clarified. We investigated symptom-related QOL impairment that led patients to seek medical care. Patients and MethodsAbdominal symptom-related QOL was determined using the Izumo scale instrument in 172 patients who visited a clinic for their abdominal symptoms and in 961 healthy subjects who attended an annual health check. Results QOL was more strongly impaired in the patients with abdominal symptoms than in subjects who attended health checks. Patients with heartburn consulted physicians even when QOL impairment was minimal, while those with epigastric fullness tended to consult a physician only when QOL impairment was significant. Conclusion Abdominal symptom-related QOL impairment is considered to lead patients to seek medical care, though different symptoms have varying levels of influence.

show abstract

Section: Discussionmentioning

confidence: 99%

Abdominal Symptom-related QOL in Individuals Visiting an Outpatient Clinic and those Attending an Annual Health Check

et al. 2011

View full text Add to dashboard Cite

show abstract

“…Three studies using the Medical Outcomes Study Short Form-36 (SF-36) demonstrated that HR-QOL in GERD patients was lower than that in the general Japanese population. [66][67][68] A recent study by Hongo et al [69] using a new questionnaire (QOLRAD) which has been developed as a specific QOL assessment of GERD, showed impairment of HR-QOL in GERD patients.…”

Section: Prevalence and Clinical Characteristics Of Symptomatic Gerd mentioning

confidence: 99%

Epidemiology and clinical characteristics of GERD in the Japanese population

2009

View full text Add to dashboard Cite

We reviewed articles on the epidemiology and clinical characteristics of gastroesophageal reflux disease (GERD) in Japan to clarify these features of GERD in this country. Although the definition of GERD depends on the individual study, the prevalence of GERD has been increasing since the end of the 1990s. The reasons for the increase in the prevalence of GERD may be due to increases in gastric acid secretion, a decrease in the Helicobacter pylori infection rate, more attention being paid to GERD, and advances in the concept of GERD. More than half of GERD patients had non-erosive reflux disease, and the majority (87%) of erosive esophagitis was mild type, such as Los Angeles classification grade A and grade B. There were several identified risk factors, such as older age, obesity, and hiatal hernia. In particular, mild gastric atrophy and absence of H. pylori infection influence the characteristics of GERD in the Japanese population. We also discuss GERD in the elderly; asymptomatic GERD; the natural history of GERD; and associations between GERD and peptic ulcer disease and H. pylori eradication. We examined the prevalence of GERD in patients with specific diseases, and found a higher prevalence of GERD, compared with that in the general population, in patients with diabetes mellitus, those with obstructive sleep apnea syndrome, and those with bronchial asthma. We provide a comprehensive review of GERD in the Japanese population and raise several clinical issues.

show abstract

“…The prevalence of the symptoms respectively in males and females were: heartburn, 15.8% (sometimes 15.3%, usually 0.5%) vs 20.7% (sometimes 20.1%, usually 0.6%); dysphagia, 5.4% (sometimes 5.0%, usually 0.4%) vs 7.8% (sometimes 7.3%, usually 0.5%); and abdominal pain, 6.6% (sometimes 6.5%, usually 0.1%) vs 9.6% (sometimes 9.4%, usually 0.2%). Among these symptoms, heartburn was significantly high compared with the other symptoms, and all symptoms were significantly more common in females than in males.…”

Section: Frequency Of Respective Symptomsmentioning

confidence: 99%

“…Some studies have reported acid suppressive therapy resolves epigastric pain in patients with GERD [5,6] . According to these studies, epigastric pain might be one of the clinical symptoms of GERD.…”

Section: Figurementioning

confidence: 99%

“…Recent studies have suggested GERD causes a wide spectrum of non-esophageal conditions including asthma, non-obstructive dysphagia, and noncardiac chest pain [3,4] . Moreover, it has been reported that acid-suppressive therapy resolves heartburn and epigastric pain in GERD patients [5,6] . Therefore, epigastric pain may be a clinical symptom of GERD.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of gastroesophageal reflux symptoms in a large unselected general population in Japan

Yamagishi¹,

Koike²,

Ohara³

et al. 2008

WJG

View full text Add to dashboard Cite

AIM:To examine the prevalence of gastroesophageal reflux disease (GERD) symptoms in a large unselected general population in Japan. METHODS:In Japan, mature adults are offered regular check-ups for the prevention of gastric cancer. A notice was sent by mail to all inhabitants aged > 40 years. A total of 160 983 Japanese (60 774 male, 100 209 female; mean age 61.9 years) who underwent a stomach check up were enrolled in this study. In addition, from these 160 983 subjects, we randomly selected a total of 82 894 (34 275 male, 48 619 female; mean age 62.4 years) to evaluate the prevalence of abdominal pain. The respective subjects were prospectively asked to complete questionnaires concerning the symptoms of heartburn, dysphagia, and abdominal pain for a 1 mo period. RESULTS:The respective prevalences of the symptoms in males and females were: heartburn, 15.8% vs 20.7%; dysphagia, 5.4% vs 7.8%; and abdominal pain, 6.6% vs 9.6%. Among these symptoms, heartburn was significantly high compared with the other symptoms, and the prevalence of heartburn was significantly more frequent in females than in males in the 60-89-year age group. Dysphagia was also significantly more frequent in female patients. CONCLUSION:The prevalence of typical G ERD symptoms (heartburn) was high, at about 20% of the Japan population, and the frequency was especially high in females in the 60-89 year age group.

show abstract

Famotidine vs. omeprazole: a prospective randomized multicentre trial to determine efficacy in non‐erosive gastro‐oesophageal reflux disease

Cited by 34 publications

References 43 publications

Abdominal Symptom-related QOL in Individuals Visiting an Outpatient Clinic and those Attending an Annual Health Check

Abdominal Symptom-related QOL in Individuals Visiting an Outpatient Clinic and those Attending an Annual Health Check

Epidemiology and clinical characteristics of GERD in the Japanese population

Prevalence of gastroesophageal reflux symptoms in a large unselected general population in Japan

Contact Info

Product

Resources

About