Family History, Blood Pressure and Life Style. Results From Ehuh Study

Krtalic, B.; Knežević, Tamara; Željković-Vrkić, Tajana; Kos, Janko; Pećin, Ivan; Gellineo, Lana; Golubic, I.; Jelaković, Ana; Dika, Živka; Jug, Juraj; Jelaković, Bojan

doi:10.1097/01.hjh.0000572956.60503.d4

Cited by 6 publications

(5 citation statements)

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“…Our results demonstrated that those having a family history of hypertension was more likely to be hypertensive (adjusted adds ratio = 1.8), more likely to be aware (adjusted adds ratio = 1.8) and controlled (adjusted adds ratio = 1.8), in line with previous studies [ 56 57 ]. This confirms the hereditary pattern of hypertension [ 58 ].…”

Section: Discussionsupporting

confidence: 92%

Epidemiologic Profile of Hypertension in Northern Iranian Population: The PERSIAN Guilan Cohort Study (PGCS)

Naghipour

Joukar

Salari

et al. 2021

Annals of Global Health

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Background: Estimates region-related prevalence of hypertension and attempts to identify its related factors at the district levels are required for prevention and management of hypertension. Objective: The aim of this study was to investigate the epidemic features and related factors of hypertension and its awareness, treatment, and control rates among the northern Iranian population. Methods: It was a community based cross-sectional study based on data from PERSIAN Guilan Cohort Study (PGCS). In total, 10,520 participants (aged 35–70 years) from the Guilan Province in northern Iran included in this study, between October 8, 2014, and January 20, 2017. Hypertension was defined as systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg or a prior diagnosis of hypertension or being on antihypertensive medication. Potential correlates of hypertension and its awareness, treatment and control were analyzed by multivariate logistic regression adjusted for demographic factors, anthropometric characteristics, lifestyle variables, past medical history, and laboratory data. Results: The prevalence of hypertension was 43.2% and the hypertension awareness, treatment, and control rate were 53.4%, 49.8%, and 73.7%, respectively. The multivariate logistic regression analyses revealed that older age, urbanization, lower education, overweight and obesity, lower physical activity, prediabetes and diabetes, cardiovascular disease, psychiatric disorder, positive family history of hypertension and raised serum creatinine were independently associated with presence of hypertension. Awareness of hypertension was greater in the female sex, older age, rural residency, higher education and patient with comorbidities. Older age, rural residency and comorbidities were associated with treatment of hypertension. Control of hypertension was better among younger age, higher education, normal weight and higher physical activity. Conclusion: Hypertension is highly prevalent in the northern Iranian population. About half of affected persons are unaware of their disease and untreated. Modifying risk factors (such as weight lose and increase physical activity) and increasing hypertension awareness (by screening) is essential for primary and secondary prevention of high blood pressure in this population, especially in urban areas and among males, younger ages, and less educated.

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Section: Discussionsupporting

confidence: 92%

Epidemiologic Profile of Hypertension in Northern Iranian Population: The PERSIAN Guilan Cohort Study (PGCS)

Naghipour

Joukar

Salari

et al. 2021

Annals of Global Health

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“…We found no association between the PRS for SBP and DBP and HBP in the adolescents, even when we ran the analyses after excluding the family history of AH variable from the adjusted model. The risk of AH in individuals with a family history is much higher compared with nonrelatives in the general population, 45 which is consistent with our finding of an association between a family history of AH and HBP among female adolescents. Genome‐wide association studies have identified many BP loci, although each individually accounts for slight BP differences (<1 mm Hg).…”

Section: Discussionsupporting

confidence: 91%

Prevalence of and Factors Associated With High Blood Pressure at 15 Years of Age: A Birth Cohort Study

Petracco,

Mattiello,

Bortolotto

et al. 2023

JAHA

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Background Arterial hypertension is the greatest cause of morbidity and mortality worldwide. Our aim was to investigate the prevalence of and factors associated with high blood pressure (HBP) among adolescents. Methods and Results The Pelotas 2004 Birth Cohort included 4231 newborns from hospital births in Pelotas, Brazil. A digital automatic OMRON sphygmomanometer (model HEM 742) was used to measure blood pressure on 3 occasions (at 6, 11, and 15 years of age). Those with blood pressure ≥95th percentile for age, height, and sex on each of the 3 occasions were considered as presenting HBP. Independent variables included family (income and history of arterial hypertension), maternal (schooling, age, pregestational body mass index, and smoking during pregnancy), and adolescent characteristics at birth (sex, skin color, gestational age, intrauterine growth, and systolic and diastolic genetic factors), and at 15 years (sleep, physical activity, sodium intake, screen time, work, body mass index, fat mass index, fat‐free mass index, growth pattern, and puberty status). The prevalence of HBP (95% CI) was calculated. Crude and adjusted odds ratios (ORs) stratified by sex were obtained by logistic regression. A total of 1417 adolescents with complete information on blood pressure on the 3 occasions were analyzed. The prevalence of HBP was 3.2% (95% CI, 1.9%–4.5%) in female adolescents and 4.3% (95% CI, 2.8%–5.8%) in male adolescents. Female adolescents with a family history of arterial hypertension had a 3 times higher chance of HBP than their counterparts (OR, 3.1 [95% CI, 1.26–7.54]). In male adolescents, excessive maternal pregestational weight was associated with a 2.3‐fold increase in the chance of HBP. In both sexes, excessive adolescent weight was associated with HBP (ORs, 3.5 and 5.0, for female and male adolescents, respectively). A higher fat mass index and fat‐free mass index in female (ORs, 1.4 and 1.2, respectively) and male adolescents (ORs, 2.5 and 3.0, respectively) increased the chance of HBP. Among male adolescents, the chance of HBP was higher among those with rapid weight gain between 48 months and 6 years and between 6 and 11 years and rapid height gain between 6 and 11 years. Conclusions Higher fat mass in both sexes and rapid weight gain in male adolescents are risk factors for HBP in adolescents aged 15 years, potentially amenable to prevention.

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“…Individuals who are raised in a family that lacks awareness of healthy eating and physical activity may have a higher risk of developing prehypertension and hypertension compared to those raised in families practicing healthy lifestyles. 41 , 42 In addition, studies have shown that genetic factors, such as high sodium–lithium countertransport, elevated uric acid levels, high fasting plasma insulin concentrations, fat pattern index, and BMI can contribute to the relationship between hypertension and family history. 43 , 44 , 45 …”

Section: Discussionmentioning

confidence: 99%

Prevalence and Factors Associated with Prehypertension and Hypertension Among Adults: Baseline Findings of PURE Malaysia Cohort Study

Ismail

Isa

Tamil

et al. 2023

American Journal of Medicine Open

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Family History, Blood Pressure and Life Style. Results From Ehuh Study

Cited by 6 publications

References 0 publications

Epidemiologic Profile of Hypertension in Northern Iranian Population: The PERSIAN Guilan Cohort Study (PGCS)

Epidemiologic Profile of Hypertension in Northern Iranian Population: The PERSIAN Guilan Cohort Study (PGCS)

Prevalence of and Factors Associated With High Blood Pressure at 15 Years of Age: A Birth Cohort Study

Prevalence and Factors Associated with Prehypertension and Hypertension Among Adults: Baseline Findings of PURE Malaysia Cohort Study

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