Family Functioning, Comorbidities, and Behavioral Profiles of Children With ADHD and Disruptive Mood Dysregulation Disorder

Uran, Pınar; Kılıç, Birim Günay

doi:10.1177/1087054715588949

Cited by 18 publications

(16 citation statements)

References 28 publications

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“…Interestingly, the percentage of securely attached children and mothers in the clinical sample was, respectively, 51% ( N = 43) and 45% ( N = 38), much lower than in the control sample, with 75% ( N = 48) and 66% ( N = 42) of youths and mothers, respectively, displaying secure attachment. This observation confirms that children with DMDD experience difficulties in constructing and maintaining positive affective relationships with their caregivers, as suggested in other studies (American Psychiatric Association, 2013; Bell, 1979; Cerniglia, Cimino, Tafà, & Marzilli, 2017; Cicchetti, Toth, & Handley, 2015; Fonagy & Target, 2005; Sameroff, 1975; Uran & Family, 2015). The mothers of these children, on the other hand, showed low rates of secure attachment to their own mothers.…”

Section: Discussionsupporting

confidence: 89%

The μ‐opioid receptor gene A118G polymorphism is associated with insecure attachment in children with disruptive mood regulation disorder and their mothers

et al. 2020

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Background The A118G single nucleotide polymorphism (SNP) of the μ‐opioid receptor gene, with high expression of the A allele and low expression of the G allele, has been associated with emotional/behavioral dysregulation and depressive disorders and is recognized as a mediator of affiliative behavior. No study has thus far investigated this SNP in school‐age children with disruptive mood regulation disorder (DMDD). This study compared a sample of healthy children and their mothers with a sample of children with DMDD and their mothers, evaluating whether insecure attachment and psychopathological symptoms are associated with A allele‐ or G allele‐carrying mothers and children and whether caregiving capacities are associated with A allele‐ or G allele‐carrying mothers. Methods For evaluation of their psychopathological symptoms and attachment styles, mothers filled out the CBCL/6‐18, the SCL‐90‐R, and the ECR. To evaluate the types of relationship children were experiencing with their mothers, children filled out the ECR‐revised child version and the PBI. Genotypic analyses were conducted on DNA samples obtained by buccal swabbing from children and mothers. Results An insecure attachment style was more frequent in mothers and children carrying the G allele (G/G + A/G genotypes). In the clinical sample, G allele‐carrying children scored higher than homozygous A/A ones on the subscales of Withdrawal and Conduct Problems. G‐carrying mothers showed higher interpersonal sensitivity, depression, hostility, and paranoid ideation and provided less care than A/A mothers. Conclusions This study offers new insights into the associations between the A118G SNP of the μ‐opioid receptor gene and emotional/behavioral functioning, attachment style in children, and psychopathology and caregiving ability in mothers.

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Section: Discussionsupporting

confidence: 89%

The μ‐opioid receptor gene A118G polymorphism is associated with insecure attachment in children with disruptive mood regulation disorder and their mothers

et al. 2020

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Section: Case Conceptualizationmentioning

confidence: 74%

“…For Bella, however, her prolonged instances of angry and irritable mood in between temper outbursts indicated a diagnosis of DMDD. It is also important to note that early onset of ADHD and co-occurring symptoms of anxiety are also consistent with the diagnosis of DMDD (Dougherty et al, 2014;Mulraney et al, 2015;Uran & Kılıç, 2015). Although Bella demonstrated many strengths, such as athletic ability and sense of humor, many of her social experiences became overshadowed by negative interactions, which were interfering with her enjoyment of home and school life.…”

Section: Case Conceptualizationmentioning

confidence: 76%

Cognitive-Behavioral Therapy for a 9-Year-Old Girl With Disruptive Mood Dysregulation Disorder

Tudor

Ibrahim

Bertschinger

et al. 2016

Clinical Case Studies

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Disruptive mood dysregulation disorder (DMDD) is a relatively new diagnosis in the field of childhood onset disorders. Characterized by both behavior and mood disruption, DMDD is a purportedly unique clinical presentation with few relevant treatment studies to date. The current case study presents the application of cognitive-behavioral therapy (CBT) for anger and aggression in a 9-year-old girl with DMDD, co-occurring attention deficit hyperactivity disorder (ADHD), and a history of unspecified anxiety disorder. At the time of intake evaluation, she demonstrated three to four temper outbursts and two to three episodes of aggressive behavior per week, in addition to prolonged displays of non-episodic irritability lasting hours or days at a time. A total of 12 CBT sessions were conducted over 12 weeks and 5 follow-up booster sessions were completed over a subsequent 3-month period. Irritability-related material was specially designed to target the DMDD clinical presentation. Post-treatment and 3-month follow-up assessments, including independent evaluation, demonstrated significant decreases in the target symptoms of anger, aggression, and irritability. Although the complexities of diagnosing and treating DMDD warrant extensive research inquiry, the current case study suggests CBT for anger and aggression as a viable treatment for affected youth.

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“…Finally, in Uran's study [30], it appears that children with DMMD have a higher comorbidity rate than those with ADHD. Results showed that DMDD children's average scores were higher than ADHD children in Conners and in "Communication", "Affective Responsiveness", "Affective Involvement" and "General Functioning" subscales of Family Assessment Device (FAD).…”

Section: Distinctionsmentioning

confidence: 91%

ADHD and DMDD Comorbidities, Similarities and Distinctions

Masi¹,

Gignac²

2016

J Child Adolesc Behav

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Since the mid-90s, the number of children treated for bipolar disorder has increased considerably. Although the need to avoid a confusing terminology regarding bipolar disorder was generally accepted, agreement on diagnosis for this population was difficult to conclude. In particular, the controversy concerned children with chronic irritability and high comorbidity with ADHD. The DSM-5 working group on mood disorders proposed a new diagnosis: Dysruptive Mood Dysregulation Disorder (DMDD). If the distinction with bipolar appears now clear, high comorbidity with ADHD is concerning and makes the nosological limits unclear. However, differences are present and these two diseases must be distinguished in order to recognize their particular problems. Investigation of overlaps between ADHD and DMDD should help clarify their etiology, course and outcome.

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Family Functioning, Comorbidities, and Behavioral Profiles of Children With ADHD and Disruptive Mood Dysregulation Disorder

Abstract: Children with DMDD were distinguished from children with ADHD-C by their higher comorbidity rate, more impaired behavioral patterns, and family functioning.

Cited by 18 publications

References 28 publications

The μ‐opioid receptor gene A118G polymorphism is associated with insecure attachment in children with disruptive mood regulation disorder and their mothers

The μ‐opioid receptor gene A118G polymorphism is associated with insecure attachment in children with disruptive mood regulation disorder and their mothers

Cognitive-Behavioral Therapy for a 9-Year-Old Girl With Disruptive Mood Dysregulation Disorder

ADHD and DMDD Comorbidities, Similarities and Distinctions

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