Abstract:AimsPostoperative cognitive dysfunction (POCD) is a common complication associated with poor outcome. Our previous study has shown that living with familiar observers in the same cage reduces anxiety of mice with surgery. Anxiety can impair learning and memory. Thus, this study was designed to determine whether living with familiar observers attenuated the dysfunction of learning and memory of mice with surgery.MethodsSix‐ to eight‐week‐old CD‐1 male mice or 18‐month‐old C57BL/6 male mice had left carotid arte… Show more
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