Familial combined duodenal and jejunal atresia

Colonic atresia without mesenteric vascular occlusion. The role of the fibroblast growth factor 10 signaling pathway

“…Familial hereditary forms of duodenal, jejuno-ileal, colonic, and multiple atresias have been reported clinically. The associated presence of nongastrointestinal developmental defects raises the possibility of intestinal atresia being a heritable condition in some cases [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20].…”

The fibroblast growth factor pathway serves a regulatory role in proliferation and apoptosis in the pathogenesis of intestinal atresia

“…Clinically, familial hereditary forms of duodenal, jejunoileal, colonic, and multiple atresias have been reported. The associated presence of nongastrointestinal developmental defects raises the possibility of intestinal atresia being a heritable condition in some cases [3][4][5][6][7][8][9][10][11][12][13][14].…”

A proposed classification system for familial intestinal atresia and its relevance to the understanding of the etiology of jejunoileal atresia

“…Three individuals in one family had simple, single jejunoileal atresia associated with renal dysplasia [44,45]. Another family had 2 siblings with both duodenal atresia and proximal jejunal atresia [46]; and a third family had 2 siblings with duodenal atresia and malrotation as well as a second cousin with a proximal jejunal atresia and malrotation [47]. In the absence of any other reports of the same complex of anomalies, the significance of the findings in each of these families is uncertain.…”