False‐mildew (Phytophtora Infestans) as an Allergenic Factor

Liebeskind, A

doi:10.1111/j.1398-9995.1969.tb03749.x

Cited by 6 publications

(2 citation statements)

References 2 publications

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“…With regard to the effect of tetracycline on yeasts, the results of the present study confirm the view held by many that broad‐spectrum antibiotics suppress the normal intestinal flora, thus encouraging an overgrowth of fungus, the most common of these being Candida albicans (Childs 1956; Dunlop et al 1950; Cormane & Gosling 1963; Liebeskind 1962). Such an overgrowth may or may not give rise to symptoms at this stage.…”

Section: Discussionsupporting

confidence: 87%

The Effect of Nystatin on the Growth of Candida Albicans during short term Tetracycline therapy

Middleton¹

1967

Int J Clinical Practice

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Section: Discussionsupporting

confidence: 87%

The Effect of Nystatin on the Growth of Candida Albicans during short term Tetracycline therapy

Middleton¹

1967

Int J Clinical Practice

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“…Two members of this order, Phytophthora infestans and Plasmopara viticola, have been implicated as allergenic fungi. One early report provided circumstantial evidence for the induction of allergic asthma in three members of the same household following exposure to Phytophthora infestans on moldy potatoes (112). This study did not include controls, however.…”

Section: Oomycetesmentioning

confidence: 97%

Fungal allergens

et al. 1995

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Airborne fungal spores occur widely and often in far greater concentrations than pollen grains. Immunoglobulin E-specific antigens (allergens) on airborne fungal spores induce type I hypersensitivity (allergic) respiratory reactions in sensitized atopic subjects, causing rhinitis and/or asthma. The prevalence of respiratory allergy to fungi is imprecisely known but is estimated at 20 to 30% of atopic (allergy-predisposed) individuals or up to 6% of the general population. Diagnosis and immunotherapy of allergy to fungi require well-characterized or standardized extracts that contain the relevant allergen(s) of the appropriate fungus. Production of standardized extracts is difficult since fungal extracts are complex mixtures and a variety of fungi are allergenic. Thus, the currently available extracts are largely nonstandardized, even uncharacterized, crude extracts. Recent significant progress in isolating and characterizing relevant fungal allergens is summarized in the present review. Particularly, some allergens from the genera Alternaria, Aspergillus, and Cladosporium are now thoroughly characterized, and allergens from several other genera, including some basidiomycetes, have also been purified. The availability of these extracts will facilitate definitive studies of fungal allergy prevalence and immunotherapy efficacy as well as enhance both the diagnosis and therapy of fungal allergy.

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