Failure Analysis of Dental Prosthesis

Miculescu, Florin; Ciocan, Lucian Toma; Miculescu, Marian; Berbecaru, Andrei; Oliva, Josep; Comăneanu, Raluca Monica

doi:10.1007/978-3-319-09230-0_56-1

Cited by 3 publications

(5 citation statements)

References 36 publications

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“…Not all the components were recognizable due to the complexity of the natural tissue and, even if they were detected in previous studies, they remain not assigned. [ 59,60 ] Quantitatively, the final residue in the range of 36%–39% was in accordance with a previous study (35.6% and 36.4%). [ 61 ]…”

Section: Discussionsupporting

confidence: 90%

Modeling the Osteogenic Potential of Decellularized Human Bone Particles by Tuning their Size Distribution Through a Sonic Microfragmentation Approach

Bucciarelli,

Pedranz,

Gambari

et al. 2023

Adv Materials Technologies

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Human decellularized bone fragments are commonly used in clinics to perform allograft surgeries. To reduce the immunological response in the recipient and ensure their safety, these fragments underwent decellularization, a procedure that greatly reduces their osteogenicity (the ability to induce differentiation into osteoblast). In this work, by the introduction of an ultrasonication step to fragment the human bone, the size distribution of the resulting demineralize bone particles can be controlled, tuning their osteogenic potential. The sonication protocol is optimized by a response surface method, using 12 different sonication protocols, allowing to model the relationship between the sonication parameters and the outcoming particles properties in terms of dimensions, physical/chemical properties, and biological activity. The size distribution is extrapolated by a deep learning image segmentation while the structure is characterized by infrared and thermal analysis. The particles are combined with methacrylated silk gel to test in vitro their biological response on adipose‐derived stromal cells. The ultrasonication fragmented the bone particles, revealing their internal organic matrix as proved by secondary electron microscopy and confocal microscopy. An inverse linear correlation is found between the particles’ sizes and their osteogenic activity, thus proving the efficacy of the proposed ultrasonication treatment in tuning the biological response.

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Section: Discussionsupporting

confidence: 90%

Modeling the Osteogenic Potential of Decellularized Human Bone Particles by Tuning their Size Distribution Through a Sonic Microfragmentation Approach

Bucciarelli,

Pedranz,

Gambari

et al. 2023

Adv Materials Technologies

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“…As our results show, the groups with added ASCs present statistically significant better cartilage formation than the control group, where the collagen I/III membrane was implanted without adding cells, although with this method there are very good results reported in the literature [28][29][30]. The utilization of a validated chondrogenic scaffold (Chondro-Gide®; Geistlich Pharma AG, Wolhusen, Switzerland) [31][32][33] eliminated the risk of bias due to surgical procedure and implants.…”

Section: Histologic Evaluationmentioning

confidence: 99%

Collagen Scaffold and Lipoaspirate Fluid-derived Stem Cells for the Treatment of Cartilage Defects in a Rabbit Model

Benea¹,

Earar²,

Lattanzi³

et al. 2018

Rev. Chim.

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The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.

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“…In clinical practice, many surgical interventions need the support given by the synthetic biomaterials. Also, the various aspects related to the interface between synthetic biomaterials and human tissue appear to be interesting not just for neurosurgery [1,2], but also for many clinical specializations like orthopedics [3][4][5][6][7], dentistry [8][9][10], abdominal surgery [11][12][13][14], gynecology [15][16][17][18], cardiovascular surger y [19,20], and ophthalmology [21].…”

mentioning

confidence: 99%

“…However, cranioplasty can present different complications like excessive inflammation, infection, dislocation, bone resorbtion, convulsions, excessive bleeding quickly turning into haemorrhage and even intracranial hematomas. Many of these complications appear based on the dimension and localization of the defect more than on the type of material used for bone reconstruction [10,23].…”

mentioning

confidence: 99%

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Influence of the Bone Cements Processing on the Mechanical Properties in Cranioplasty

Riviș¹,

Pricop²,

Talpoș³

et al. 2018

Rev. Chim.

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The aim of this study is to observe the time of mixing influence on the properties of commercially available PMMA bone cement, widely used in cranioplasty. The studied bone cement is provided in the form of a solid powder (the copolymer) and a liquid monomer. The increase of the mixing phase duration and the use of two mixing methods (manual and mechanical) effect on surface and mechanical characteristics were studied. The samples were prepared as if in the operation room. Surface characteristics were studied by means of contact angle measurements, morphology by scanning electron microscopy (SEM) and mechanical characteristics determined by flexural tests in a three point bending configuration. The conclusion of this study is that by using a mechanical mixing method and increasing mixing time higher flexural strength can be achieved by reducing pore content within bone cement.

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Failure Analysis of Dental Prosthesis

Cited by 3 publications

References 36 publications

Modeling the Osteogenic Potential of Decellularized Human Bone Particles by Tuning their Size Distribution Through a Sonic Microfragmentation Approach

Modeling the Osteogenic Potential of Decellularized Human Bone Particles by Tuning their Size Distribution Through a Sonic Microfragmentation Approach

Collagen Scaffold and Lipoaspirate Fluid-derived Stem Cells for the Treatment of Cartilage Defects in a Rabbit Model

Influence of the Bone Cements Processing on the Mechanical Properties in Cranioplasty

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