Facts and Artefacts in Bone Densitometry

Gnanasegaran, Gopinath; Blake, Glen M.; Crane, F.M.; Dulnoan, Dwight; Clarke, S. E.M.; Fogelman, I; Fogelman, Ignac

doi:10.2174/157340507779940318

Cited by 3 publications

(2 citation statements)

References 13 publications

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“…2B). Treatment of vertebral fractures by vertebroplasty will also increase the measured BMD, owing to density of the polymethylmethacrylate cement preparation, which has purposefully been rendered radiopaque 44,45 (Fig. 2C).…”

Section: Osseous Conditions With Focal Increase In Bmd Measurementsmentioning

confidence: 99%

Artifacts and Incidental Findings Encountered on Dual-Energy X-Ray Absorptiometry: Atlas and Analysis

Martineau

Bazarjani

Zuckier

2015

Seminars in Nuclear Medicine

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Section: Osseous Conditions With Focal Increase In Bmd Measurementsmentioning

confidence: 99%

Artifacts and Incidental Findings Encountered on Dual-Energy X-Ray Absorptiometry: Atlas and Analysis

Martineau

Bazarjani

Zuckier

2015

Seminars in Nuclear Medicine

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“…Thus, superimposed dense tissues can skew the measurements toward artifactually high values . Even more importantly, metal in the region of interest may result in elevated BMD values …”

mentioning

confidence: 99%

Agreement and precision of periprosthetic bone density measurements in micro-CT, single and dual energy CT

Mussmann¹,

Overgaard

Torfing³

et al. 2016

J. Orthop. Res.

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The objective of this study was to test the precision and agreement between bone mineral density measurements performed in micro CT, single and dual energy computed tomography, to determine how the keV level influences density measurements and to assess the usefulness of quantitative dual energy computed tomography as a research tool for longitudinal studies aiming to measure bone loss adjacent to total hip replacements. Samples from 10 fresh-frozen porcine femoral heads were placed in a Perspex phantom and computed tomography was performed with two acquisition modes. Bone mineral density was calculated and compared with measurements derived from micro CT. Repeated scans and dual measurements were performed in order to measure between- and within-scan precision. Mean density difference between micro CT and single energy computed tomography was 72 mg HA/cm . For dual energy CT, the mean difference at 100 keV was 128 mg HA/cm while the mean difference at 110-140 keV ranged from -84 to -67 mg HA/cm compared with micro CT. Rescanning the samples resulted in a non-significant overall between-scan difference of 13 mg HA/cm . Bland-Altman limits of agreement were wide and intraclass correlation coefficients ranged from 0.29 to 0.72, while 95% confidence intervals covered almost the full possible range. Repeating the density measurements for within-scan precision resulted in ICCs >0.99 and narrow limits of agreement. Single and dual energy quantitative CT showed excellent within-scan precision, but poor between-scan precision. No significant density differences were found in dual energy quantitative CT at keV-levels above 110 keV. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:1470-1477, 2017.

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US White and Black Women Do Not Represent the Bone Mineral Density of Sub-Saharan Black Women

Mukwasi

Chibanda

Banhwa

et al. 2015

Journal of Clinical Densitometry

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Facts and Artefacts in Bone Densitometry

Cited by 3 publications

References 13 publications

Artifacts and Incidental Findings Encountered on Dual-Energy X-Ray Absorptiometry: Atlas and Analysis

Artifacts and Incidental Findings Encountered on Dual-Energy X-Ray Absorptiometry: Atlas and Analysis

Agreement and precision of periprosthetic bone density measurements in micro-CT, single and dual energy CT

US White and Black Women Do Not Represent the Bone Mineral Density of Sub-Saharan Black Women

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