Factors related to the effectiveness of hypercholesterolemia treatment following hospitalization for coronary artery disease

Abstract

in patients with CAD. 1,2 One of the most important risk factors is hypercholesterolemia, while the use of statins is related to improved prognosis. The European guidelines recommend lowering low-density lipoprotein (LDL) cholesterol levels below 1.8 mmol/l in all coronary patients. 3,4 INTRODUCTION Patients with established coronary artery disease (CAD) are at high risk of recurrent cardiovascular events. Despite advances in pharmacological and invasive treatment methods, a number of risk factors remain independent predictors of cardiovascular mortality

Adherence to treatment — a pivotal issue in long-term treatment of patients with cardiovascular diseases. An expert standpoint

“…Jankowski at al. [46] pointed out different healthcare-related factors and patient-related factors affecting proper treatment of patients with cardiovascular diseases. According to Jankowska-Polanska at al.…”

Changes in the prevalence, management and treatment of hypercholesterolemia and other dyslipidemias over 10 years in Poland. The WOBASZ study

“…In the Polish part of the EUROASPIRE IV study, over 80% of patients were taking lipid-lowering medication (36% statins at high dose). 22,23 Nevertheless, overall, only about 25% were at treatment target of LDL-C of less than 1.8 mmol/l, which is, in any case, a 2-fold difference from the very high-risk group in the general population. 22,23 The use of moderate-intensity and high-intensity statin therapy in WOBASZ II seems to be more frequent than that found in the 3ST-POL study of nearly 50 000 ambulatory patients in Poland before 2010, in which almost 71% of patients received the daily statin dose of less than 20 mg.…”

Treatment and outcomes of patients under 40 years of age with acute myocardial infarction in Poland in 2009-2013 (analysis from PL-ACS Registry)

“…19,20 The second frequent risk factor in our study was hypertension, observed in over 40% of the patients. The incidence of hypertension in young patients with AMI seems to have increased over the years.…”