Factors Related to Corneal Epithelial Complications After Closed Vitrectomy in Diabetics

Changes in corneal sensation following 20 and 23 G vitrectomy in diabetic and non-diabetic patients

“…[1][2][3][4][5][6] Systemic predisposing factors include diabetes mellitus and neurological disorders affecting sensory innervations. [1][2][3][4][5][6] Diabetic neurotrophic keratopathy is a component of diabetic polyneuropathy and is recognized to be a cause of corneal morbidity. 13 Local predisposing factors are herpetic eye diseases, previously traumatized, glaucoma, and chronic use of topical medications.…”

“…Other surgical factors that might increase the rate of corneal complications postoperatively; are surgical time and intraoperative epithelial debridement. [1][2][3][4][5][6] We did not need to do any surgical debridement and the surgical times between groups were similar. It is interesting to note that none of the study cases had any complications, this is could be probably attributed to improved surgical techniques and equipment.…”

“…Significant predisposing factors include diabetes, surgical trauma such as epithelial debridement and prolonged operative surgery time, aphakia, and postoperative glaucoma or hyphema. [1][2][3][4][5][6] One of the pathological changes that has been described and found to be positively correlated with an increased incidence of post vitrectomy corneal complication is reduced corneal sensitivity. 3 Multiple factors have been described that predispose to increased incidence of reduced corneal sensitivity postoperative including diabetes mellitus, neurological disorders, herpetic eye diseases, previous mechanical or surgical corneal trauma, and chronic use of topical eye drops.…”

“…[1][2][3][4][5][6] Slow or non-healing epithelial abrasions, recurrent corneal erosions, and corneal edema are among the most frequent problems. Significant predisposing factors include diabetes, surgical trauma such as epithelial debridement and prolonged operative surgery time, aphakia, and postoperative glaucoma or hyphema.…”

“…In addition, intraoperative direct or indirect insult (ischemia) to the two long posterior ciliary nerves may also contribute to an already compromised cornea. [1][2][3][4][5][6][7][8][9][10][11][12] In this study, we investigate the effect of diabetes and the use of different vitrectomy gauge systems (20 vs 23) on the post vitrectomy corneal sensation (CS) changes.…”