Factors Influencing the Status of the Surgical Margin in the Resection of Oral Squamous Cell Carcinoma

Payne, Kfb

doi:10.26717/bjstr.2017.01.000562

Cited by 2 publications

(1 citation statement)

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“…Maximum tumour diameter and depth of invasion were significant factors relating to poorer margins (p=0.015 and 0.021). 7 In our study more than 50% of deep tumours have close margins and more than 75% of superficial tumours have adequate margin thus signifiying the importance of DOI in local tumour control.…”

Section: Discussionsupporting

confidence: 54%

A prospective study to evaluate the impact and independency of depth of invasion in comparison with other clinicopathologic prognostic variables in oral cavity malignancy

Shanmugam

Govindasamy

Raja

2020

Int J Otorhinolaryngol Head Neck Surg

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Background: Depth of invasion is included in the staging of oral cavity malignancies in the recent 8 th edition of American Joint Committee on Cancer or tumour, node and metastasis staging system. This study analyses the impact of diffuse optical imaging (DOI) on incidence of lymph node involvement, stage migration, postoperative margin and independency. Methods: Postoperative HPE of fifty patients with oral cavity malignancy operated in our institute from January 2018 were collected. Depth of invasion and other pathological parameters were documented. DOI divided into three groups and statistical analysis done. Results: No lymph node metastasis is found in superficial tumours, 43% of intermediate thickness and 76% of deep tumours had lymph node involvement. Positive margin is seen only in patients with tumour DOI more than 0.5 cm, more than 50% of deep tumours had close margins while 75% of superficial tumours had adequate margin. Out of the 24 T3 tumours in this study 13 were upstaged due to inclusion of DOI, which would have been T2 according to the previous staging system. There is 54.1% (13 out of 24) upstaging in T3 tumours (T2 to T3), 23% (3 out of 13) in T2 (T1 to T2). There is no significant correlation between DOI and anatomical site, tumour size, tumour thickness, lymphovascular invasion and grade. Conclusions: Depth of invasion in oral cavity malignancies impacts adversely lymph node metastasis and margin status. It is an independent prognostic factor in oral cavity malignancy.

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Section: Discussionsupporting

confidence: 54%