Titanium (Ti)-Niobium (Nb) alloys are generally produced by casting methods. Since the melting temperatures of pure Ti and Nb are quite high, their fabrication by casting techniques is costly. On the other hand, it is possible to produce these alloys economically at much lower temperatures (less than melting temperature of Ti), completely in solid state using powder metallurgy. In the present study, Ti74Nb26 alloys were produced using pure Ti and pure Nb powders by combination of hot pressing and high temperature sintering for the first time. The influences of processing temperature and time on density, microstructure, and mechanical behavior were investigated. Density measurements showed that hot pressing at 800 °C provided full density. XRD and SEM investigations revealed that amount of β phase formed increased with increasing sintering time. In addition to main phase β, little amount of α phase and a very small amount of pure Nb were observed in the microstructure. Mechanical properties were measured by means of uniaxial compression and micro Vickers indentation tests. The results indicated that 4 h of sintering at 1200 °C exhibited the highest value of hardness (336 HV), elastic modulus (44 GPa), yield strength (894 MPa), and compressive strength (1178 MPa).