Factors Influencing the Alveolar-Arterial Oxygen Pressure Gradient Role of the Left Heart

Atwell, Robert J.; Ryan, Joseph M.; Hull, H; Tomashefski, Joseph F.

doi:10.1152/ajplegacy.1955.183.3.451

Cited by 7 publications

(1 citation statement)

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“…Perkins et aX. With a modified Riley technique, Atwell et al (7) found no oxygen loss across the membrane lining of the left ventricle or on the way to peripheral arteries. determina tions.…”

Section: Pulmonary Gas Exchangementioning

confidence: 98%

Respiratory System

Bjurstedt¹

1957

Annu. Rev. Physiol.

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The rapid acceleration of research activities dealing with the interaction of ventilatory, circulatory, and metabolic components in the homeostasis of the body has made even an arbitrary categorization increasingly difficult. It may therefore be justified to limit this article to recent facts and theories within a few fields of investigation which either have aroused the specific interest of the reviewer or have been marked by special progress, and to appraise the present status of these fields.Last year's review by Heemstra (98) covered much of the neurophysiol ogy of respiration, and therefore, in this review, a greater emphasis on the chemical control of respiration may be rationalized On the grounds that this topic has of late attracted increasing interest. A comprehensive monograph by Winterstein (218) should be consulted in this connection. The problems of gas exchange in the lungs are marked by a sharpened dissociation in their treatment by physicists and clinical research workers. Special mention should therefore be made of a new publication from the Rochester group (164), which aims at presenting accumtilated knowledge and new data on the complexities of gas exchange in the body in a fashion serving to bring closer the extremes. Their use of the OrC02 diagram for this purpose may safely be predicted to become a classic achievement before long. An introduc tion into the study of respiratory function is given by Cara (31), while clinical aspects of the respiratory system and various functional tests are reviewed by Christie & Bates (38). Rossier, Biihlmann & Wiesinger have written a comprehensive book on the physiology and pathophysiology of respiration (173), while interest was concentrated on the changes involved in pulmonary emphysema in a review by Ebert (66). Dripps & Severinghaus (62) and Whittenberger (213) have presented long-desired reviews on the influence of anesthesia on the respiratory system and of artificial respiration, respectively.Experimental progress in the pulmonary gas exchange area goes pari passu with our knowledge of the pulmonary circulation, and the latter has therefore been given special consideration in the present review. Many interesting papers dealing with this subject and respiratory functions may be found in a recent symposium (163).

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Section: Pulmonary Gas Exchangementioning

confidence: 98%