Factors influencing left ventricular ejection fraction in patients with coronary microvascular disease and obstructive coronary artery disease

Abstract

The aim of our research was to evaluate the relationship involving left ventricular ejection fraction, low density lipoprotein, B-type natriuretic peptide, Troponin I and coronary flow reserve, and to determine the predictors of left ventricular ejection fraction in patients with coronary microvascular disease and obstructive coronary artery disease, and in patients with coronary microvascular disease. Results: The mean age was 58.5 ± 12.5 years. In patients with obstructive coronary disease and coronary microvascular disease we found low density lipoprotein-c had significant inverse relationship with left ventricular ejection fraction, left ventricular ejection fraction also had significant negative relationship with B-type natriuretic peptide, and Troponin-I. While a significant direct relationship turned out to be observed linking left ventricular ejection fraction with coronary flow reserve. Left ventricular ejection fraction had significant negative relationship with low density lipoprotein, and B-type natriuretic peptide in patients with obstructive coronary artery disease only. Age, blood pressure, lipid levels, red cell distribution width, glycated hemoglobin, symptoms, New York heart association classification, alcohol drinking, hypertension, diabetes mellitus, troponin levels and B-type natriuretic peptide were the predictors for left ventricular ejection fraction in coronary microvascular disease patients.

A Comprehensive Analysis of Clinical, Demographic, Risk Factor, and Echocardiography Profiles of Coronary Slow Flow Phenomenon from Somalia’s Largest PCI Center

“…19 The relationship between coronary slow flow and low ejection fraction is complicated and multifaceted, involving coronary microvascular dysfunction, coronary artery disease, and their impact on left ventricular function. 20 Although some studies have not identified a statistically significant relationship between traditional cardiovascular risk factors and the coronary slow flow phenomenon, others have pointed out the association of atherosclerosis, vascular spasm, and microvascular dysfunction with the CHA2DS2-VASc score, which is commonly used to assess risk for stroke. 21,22 Complete blood cell count components have been demonstrated to be a valid and easily available predictor of cardiovascular events, especially among patients with coronary artery disease.…”

Comparison between the Levels of N Terminal Pro-Brain Natriuretic Peptide and Troponin I to Predict Left Ventricular Ejection Fraction in Patients Presenting with First ST-Elevation Myocardial Infarction

“…The left ventricular ejection fraction (LVEF) and 2 years of survival following an AMI has been predicted independently by using the values of cardiac biomarker NT-proBNP which was estimated approximately 2 to 4 days after the event. [10][11][12] There is a rapid rise in the levels of NT-proBNP over the first 24 hours after acute myocardial infarction which then tends to stabilize. After AMI the elevated levels of NT-proBNP was useful in identifying patients at risk for heart failure.…”

LDL levels and ejection fraction in ischemic stroke patients: a hospital based cross-sectional study

“…A study by Mayala et al showed a negative correlation between left ventricular ejection fraction and serum LDL cholesterol levels. 18 The limitation of this study was that it was conducted in a single tertiary care centre. Multi-centre studies with larger sample sizes are needed to be more conclusive.…”