Factors Influencing Hepatitis C Viral Infections in the Population of Algamosi Locality, Gezira State, Central Sudan

Abstract

Hepatitis C (HCV) remains a global health challenge and is transmitted via contact with contaminated blood and body fluids. This study aimed To find the factors influencing hepatitis c viral infections and to identify its prevalence among populations of the Algamosi area, Gezira state central Sudan. This cross-sectional community-based study was conducted. A total of 492 participants were randomly selected from among 4 villages and were interviewed to find out the factors that lead to transmission of infection and tested for markers of hepatitis C infection. ELISA confirmed all the positive card tests. The results showed that the individuals within the age groups > 45 and 31 -45 years are more affected by HCV the percentage was 3.37% and 0.6% respectively, while the age groups of 15 -30 and <15 years have zero prevalence 0%. There was a significant association between HCV with age groups (p < 0.05). Among the possible cause (1.4%) had a previous history of tattooing and were significantly reactive for anti-HCV (X 2 = 14.588 and p value = 0.001) The study concluded that the prevalence of hepatitis C viruses was only detected in three areas. This study explored many possible causes associated with viral hepatitis, tattooing is the common cause of hepatitis C virus. Based on the finding the study recommends, the crucial intervention program to screen most of the Algamosi population who have been not screened for HCV, proper treatment for HCV, and the health education program is strongly recommended to create awareness among the general population.

Anti-hepatitis C antibody carriage and risk of liver impairment in rural-Cameroon: adapting the control of hepatocellular carcinoma for resource-limited settings

“…While some studies reported high HCVAb carriage: in the southern 12% [ 34 ], in the western 6.3% [ 35 ], numerous studies on the contrary revealed a relative much lower prevalence: 2.2% anti-HCV in the Northern [ 27 ], 0.6% in the eastern [ 36 ], 0.4% in the western [ 37 ], 4.8% in the Littoral Region [ 38 ], 1.44% in the center region [ 39 ]. Equally, various burden of anti-HCV antibodies have also been reported in community settings worldwide: 0.77% in Romania [ 40 ], 1.02% in Sudan [ 41 ], 1.2% in Madagascar [ 42 ], 2.4%in Iraq [ 43 ], 3.6% in India [ 44 ], 19.80% in Cairo [ 45 ]. It is known that anti-HCV seropositivity from population-based studies is used to compare levels of HCV infection [ 9 ].…”

Anti-Hepatitis C Antibody Carriage and Risk of Liver Impairment in Rural-Cameroon: Adapting the Control of Hepatocellular Carcinoma for Resource-Limited Settings

“…While some studies reported high HCVAb carriage: in the southern 12% [35], in the western6.3% [36], numerous studies on the contrary revealed a relative much lower prevalence: 2.2% anti-HCV in the Northern [37], 0.6% in the eastern [38], 0.4% in the western [39], 4.8% in the Littoral Region [40], 1.44% in the center region [41]. Equally, various burden of anti-HCV antibodies have also been reported in community settings worldwide: 0.77% in Romania [42], 1.02% in Sudan [43], 1.2% in Madagascar [44], 2.4%in Iraq [45], 3.6% in India [46], 19.80% in Cairo [47]. It is known that anti-HCV seropositivity from population-based studies is used to compare levels of HCV infection [9].…”