Factors influencing contralateral lymph node metastasis from oral carcinoma

Contralateral lymph neck node metastasis of primary squamous cell carcinoma of the tongue: a retrospective analytic study of 203 patients

“…Other authors have suggested similar results, although they considered T1-T3 as earlier cancers 7,8 . In a recent study by YAO et al 19 concerning intensity-modulated radiation treatment for head and neck SCC, neither T stage nor N stage had a significant effect on local-regional control.…”

“…This value increased to 46% in cases that invaded over the midline by more than 1 cm. KOWALSKI et al 7 showed that clinical staging, tumour crossing the midline and floor of the mouth involvement were the most important predictors of contralateral metastasis. All the present cases involved the lateral side of the tongue, but midline involvement of a tumour primarily located on the lateral side of the tongue was not considered as an exclusion criterion.…”

“…In relation to SCC of the oral cavity, a variable frequency of contralateral metastasis ranging from 0.9% to 34.7% has been referred in the literature 12,18 . KOWALSKI et al 7 reported an incidence of 14% for CLNR, in concordance with that reported by KURITA et al 8 Some features may influence the appearance of CLNR. Location of the primary tumour seems to play an important role.…”

Functional imaging of head and neck cancers

“…Management of occult neck node metastasis and the role of imaging methods such as ultrasound-guided needle biopsy and SLN biopsy continues to be a matter of debate (Kowalski et al [11]), still being evaluated by various multiinstitutional groups as alternatives to elective neck dissections. Whether one of these techniques will change the current management of cervical node metastasis will definitively be proved in prospective multiinstitutional trials involving clinical follow-up and evaluation for neck recurrence.…”

Clinicopathological factors related to cervical lymph node metastasis in a patient with carcinoma of the oral floor

“…This discrimination in thickness may be due to the different method of measurement of tumor depth. Kowalski et al [15] found that clinical stage, tumor crossing midline, and oral floor involvement were the most important predictors of contralateral lymph node metastasis in oral cancer. It has been demonstrated that the risk of contralateral cervical metastases is particularly high in oral floor cancer involving the midline region [16].…”