Factors Influencing Adherence to Antiretroviral Therapy among People Living with HIV in Coastal South India

Yathiraj, Arjun Banagi; Unnikrishnan, Bhaskaran; Ramapuram, John T; Kumar, Nithin; Mithra, Prasanna; Kulkarni, Vaman; Holla, Ramesh; Bhagawan, Darshan; Thapar, Rekha

doi:10.1177/2325957416661424

Cited by 17 publications

(7 citation statements)

References 24 publications

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“…9 , 12 , 26 , 27 Similarly at-risk alcohol use has been reported to affect HIV antiretroviral adherence in South India. 28 Notably, having household contacts who drank or had at-risk alcohol use did not predict LTFU, suggesting household alcohol use does not drive adherence. Our findings suggest that in this region of India, high rates of at-risk alcohol use are driving outcomes and may subsequently impact transmission and development of drug resistance.…”

Section: Discussionmentioning

confidence: 98%

Predictors of Loss to Follow-Up among Men with Tuberculosis in Puducherry and Tamil Nadu, India

Zhou

Lakshminarayanan

Sarkar

et al. 2020

The American Journal of Tropical Medicine and Hygiene

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Identifying predictors of loss to follow-up (LTFU; treatment lapse ³ 2 months) among people with tuberculosis (TB) may assist programmatic efforts in controlling the spread of TB. Newly diagnosed smear-positive TB patients were enrolled in the Regional Prospective Observational Research for TB study in Puducherry and Tamil Nadu, India. Treatment records were used to identify LTFU of those who were enrolled from May 2014 through December 2017. This nested case-control study evaluated male TB patients. Predictors were assessed using multivariable logistic regression. Of 425 men with TB, 82 (19%) were LTFU. In the adjusted analyses of males, divorced/separated marital status (adjusted odds ratio [aOR] 3.80; 95% CI: 1.39-10.38) and at-risk alcohol use (aOR 1.92; 95% CI: 1.12-3.27) were significant predictors for increased risk of LTFU, and diabetes was a significant predictor for decreased risk of LTFU (aOR 0.52; 95% CI: 0.29-0.92). Of 53 men with recorded date of last treatment visit, 23 (43%) and 43 (81%) had LTFU within the first 2 and first 4 months of treatment, respectively. Addressing at-risk alcohol use and providing more intensive follow-up could lead to improved treatment completion.

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Section: Discussionmentioning

confidence: 98%

Predictors of Loss to Follow-Up among Men with Tuberculosis in Puducherry and Tamil Nadu, India

Zhou

Lakshminarayanan

Sarkar

et al. 2020

The American Journal of Tropical Medicine and Hygiene

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“…A meta-analysis reported that adherence is 1.74 times higher in participants from cohesive families 25. Yathiraj et al (2016) reported that the participants with a good family care (74.0%; OR = 3.0, CI=1.2, 5.2) were found to be adherent to ART (p <0.05) 27. Joseph et al (2018) found that partners/family support statistically significant associated with ART adherence (p<0.001) 28…”

Section: Discussionmentioning

confidence: 99%

<p>Factors Associated With Adherence To Anti-Retroviral Therapy Among People Living With HIV/AIDS At Wangaya Hospital In Denpasar, Bali, Indonesia: A Cross-Sectional Study</p>

Suryana¹,

Suharsono

Antara

2019

HIV

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BackgroundAcquired Immunodeficiency Syndrome (AIDS) is a major public health problem. Recently AIDS was considered as a manageable chronic disease. High adherence to Anti-Retroviral Therapy (ART) is necessary to achieve undetectable viral load, reduce morbidity, mortality and to improve the quality of life. It is also preventing the drug resistance, reducing the transmission and finally leading to live longer and healthier.ObjectivesTo assess the factor associated with ART adherence among people living with HIV/AIDS (PLWHA) at Wangaya Hospital, in Denpasar, Bali, Indonesia.MethodologyA cross-sectional study was carried out during January 2015–December 2017 among 202 PLWHA taking ART for at least 6 months. The participants were interviewed using a semi-structured questionnaire to obtain data on socio-demographic characteristics. The data were analyzed using SPSS software for windows version 24.0. Chi-square test was done, the precision value of 95% (p<0.05) was considered statistically to be significant.ResultsA total of 202 PLWHA taking ART, 170 (84.16%) were reported with high adherence (≥95%), 32 (15.84%) were low adherence (<95%). Factors found to be independently associated with high adherence to ART were employment status/occupation (p = 0.011), type of ARV (due to adverse effect of ART) (p = 0.002) and family support (p < 0.001).ConclusionThis study found that the factor associated with ART adherence among PLWHA who visited Wangaya Hospital, in Denpasar, Bali, Indonesia, was employment status, type of ARV and family support.

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“…A total of 603 articles was found using Medical Subject Headings 31 and key terms and/or phrases. After removing duplicates and irrelevant articles, we reviewed 52 full-text articles.…”

Section: Literature Search and Selection Of Eligible Articlesmentioning

confidence: 99%

HIV infection and unknown HIV status among tuberculosis patients in Ethiopia: a systematic review and meta-analysis

Endalamaw¹,

Ambachew²,

Geremew

2019

int j tuberc lung dis

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Each case of human immunodeficiency virus (HIV) infection worsens the global HIV situation, leads to the failure to achieve tuberculosis (TB) control targets worldwide, and impacts on the use of health service resources. We determined the prevalence of HIV infection among TB patients and the proportion of TB patients with unknown HIV status in Ethiopia. M E T H O D S : We searched PubMed, EMBASE, Google Scholar and Web of Science electronic databases. Heterogeneity of the included studies was checked using the I 2 statistic and publication bias was assessed using funnel plots and Egger's regression statistical test. We employed a random-effects model to determine the pooled prevalence of HIV infection and unknown HIV status. A sensitivity analysis was also conducted to examine the effect of possible outliers on the overall estimate. R E S U LT S :The prevalence of HIV infection among TB patients and the proportion of TB patients with unknown HIV status was respectively 23.4% (95%CI 19.6-27.2) and 6.4% (95%CI 1.7-11.0). Based on geographical location, the prevalence of HIV infection was 31.4% (95%CI 19.2-43.6) in Amhara Region, 23.2% (95%CI 9.9-36.5) in Oromia, 20.9% (95%CI 17.8-24.0) in Addis Ababa and 16.5% (95%CI 12.0-21.0) in Southern Nations, Nationalities and Peoples' Region (SNNPR). C O N C L U S I O N : In Ethiopia, almost one in four TB patients is infected with HIV. Given the epidemiological variation of Ethiopia, responsive, integrated sustainable programmes for HIV and TB are essential to minimise the epidemics of HIV infection and TB.

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Factors Influencing Adherence to Antiretroviral Therapy among People Living with HIV in Coastal South India

Cited by 17 publications

References 24 publications

Predictors of Loss to Follow-Up among Men with Tuberculosis in Puducherry and Tamil Nadu, India

Predictors of Loss to Follow-Up among Men with Tuberculosis in Puducherry and Tamil Nadu, India

<p>Factors Associated With Adherence To Anti-Retroviral Therapy Among People Living With HIV/AIDS At Wangaya Hospital In Denpasar, Bali, Indonesia: A Cross-Sectional Study</p>

HIV infection and unknown HIV status among tuberculosis patients in Ethiopia: a systematic review and meta-analysis

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