Factors contributing to poor treatment outcomes in childhood atopic dermatitis

Соколова, Aнна; Smith, Saxon D

doi:10.1111/ajd.12331

Cited by 41 publications

(48 citation statements)

References 71 publications

(131 reference statements)

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“…Therefore, we were unable to evaluate the actual change in TOPICOP score according to class attendance. While TCC is still a major obstacle to AD treatment, we believe that the scores before attending class might reflect data from caretakers with no attendance. Secondly, the questionnaire and the data from the medical records were not linked; therefore, the original disease severity of patients before starting treatment was unknown.…”

Section: Discussionmentioning

confidence: 98%

Topical corticosteroid phobia among caretakers of children with atopic dermatitis: A cross‐sectional study using TOPICOP in Japan

Saito‐Abe

Futamura

Yamamoto‐Hanada

et al. 2019

Pediatric Dermatology

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All the authors have approved the manuscript and agree with submission to Pediatric Dermatology.This study was carried out with the approval of the hospital ethics committee of the National Center for Child Health and Development (Reception number: 761). AbstractBackground/Objectives: The TOPICOP scale is an easy-to-use scale for assessing topical corticosteroid (TCS) phobia in atopic dermatitis (AD) patients and their caretakers. TCS phobia is a common problem among AD patients and their caretakers.The aim of this study was to examine the relationship between TCS phobia in caretakers of children with AD and the characteristics of patients using the TOPICOP scale. Methods: Caretakers of AD patients who visited the allergy clinic at the National Center for Child Health and Development in Tokyo between February 2014 and May 2014 were recruited. Caretakers of patients in follow-up had already attended an education session on treatment at the institution. All participants completed an anonymous questionnaire on the characteristics of the respondents and patients using the Patient-Oriented Eczema Measure (POEM) and the Japanese version of TOPICOP.Results: In total, 243 participants (88.9% female) completed the survey. The average TOPICOP score was 40.3 and the median POEM score was 4. The TOPICOP score was significantly higher for patients younger than 12 months old with moderate to very severe AD (POEM ≥ 8) whose caretaker had not attended an educational session (P < 0.01, respectively). There was no significant difference in the family history of AD, age, or gender of the respondents. In multivariable analysis, preattendance at an education session was the only significant factor accounting for a higher TOPICOP score (P < 0.001). Conclusions:Regardless of their background, caretakers of AD patients can be affected from TCS phobia. Attending an educational session might ease their anxiety. K E Y W O R D S atopic dermatitis, questionnaire, steroid phobia, topical corticosteroid, TOPICOP 312 | Pediatric Dermatology SAITO-ABE ET Al. Patients Age, median (range) 238 4 (range: 0-17) POEM, median (range) 243 4 (2-9) Very severe (25-28), n (%) 2 (0.8) Severe (17-24), n (%) 17 (7.0) Moderate (8-16), n (%) 60 (24.7) Mild (3-7), n (%) 72 (29.6) Clear or almost clear (0-2), n (%) 92 (37.9) AD class attendance: Preattendance, n (%) 237 95(40.1) Family history of AD, n (%) 243 143 (58.8) Mother history, n (%) 243 74 (30.5) Father history, n (%) 243 77 (31.7) Sibling history, n (%) 243 50 (20.6) a Number of respondents and patients without missing value.

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Section: Discussionmentioning

confidence: 98%

Topical corticosteroid phobia among caretakers of children with atopic dermatitis: A cross‐sectional study using TOPICOP in Japan

Saito‐Abe

Futamura

Yamamoto‐Hanada

et al. 2019

Pediatric Dermatology

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“…Corticophobia in patients has been well described in multiple studies (9-13). Possible causative factors for TCS phobia include misinformation provided by health- care providers (7,8), which may be due to TCS phobia among healthcare professionals (14)(15)(16)(17).…”

Section: Discussionmentioning

confidence: 99%

“…Fear of using corticosteroids, known as corticophobia, is a universal problem in developed countries. It is one of the main reasons for poor adherence to treatment (5)(6)(7). In chronic diseases, such as atopic dermatitis (AD), adherence to topical treatment is a key issue.…”

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confidence: 99%

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Topical Corticosteroid Phobia Among Healthcare Professionals Using the TOPICOP Score

Lambrechts¹,

Gilissen²,

Morren³

2019

Acta Derm Venerol

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Fear of using corticosteroids (corticophobia) is a universal problem and one of the main reasons for poor treatment compliance. This study examined cortico phobia among healthcare professionals (pharmacists, paediatricians, general practitioners and dermatologists) using the Topical Corticosteroid Phobia (TOPICOP) question naire. Pharmacists had the highest scores for cortico phobia (48.5 ± 13.9%), followed by general practitioners (46.0 ± 13.5%), paediatricians (39.7 ± 14.5%) and dermatologists (32.3 ± 12.1%). In conclusion, there is prominent corticophobia among healthcare professionals, especially among pharmacists and general practitioners, probably based on insufficient knowledge of topical corticosteroids. In order to improve patient compliance, re-education of healthcare providers is suggested. Corticophobia is a major problem in adherence to therapy. This study examined corticophobia among health care professionals using the Topical Corticosteroid Phobia (TOPICOP) questionnaire. The TOPICOP questionnaire was adapted for use with professionals (TOPICOP-P). Four groups of professionals: pharmacists, paediatricians, general practitioners and dermatologists were observed. The mean ± standard deviation global TOPICOP score was 41.9 ± 14.9%. Pharmacists had the highest scores for corticophobia: a global score of 48.5 ± 13.9%, followed by general practitioners, 46.0 ± 13.5%, paediatricians 39.7 ± 14.5%, and dermatologists 32.3 ± 12.1%. Overall, there was a statistically significant difference in the mean score between the 4 groups (p < 0.05). In conclusion, there is prominent corticophobia among healthcare professionals, especially among pharmacists and general practitioners, which is probably based on insufficient knowledge of topical corticosteroids. In order to improve patient compliance, re-education of healthcare providers is suggested.

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“…The AD in their children could therefore worsen to an extent where referral to larger treatment centres such as hospital-and university-based clinics that care for moderate-to-severe AD (and at the same time contribute to the Danish health registries) is necessary. 64 It is also worth noting that a child's AD may adversely influence the emotional health and social functioning of his or her parents potentially driving or worsening substance abuse issues. 65,66 In this study, no attempt was made to differentiate the possible effects of psychotropic medication use compared with the psychiatric disease itself.…”

Section: Discussionmentioning

confidence: 99%

Exploring the association between parental psychiatric disease and childhood atopic dermatitis: a matched case–control study

Hamann

Egeberg

Silverberg

et al. 2018

Acad Dermatol Venereol

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Background Maternal prenatal psychiatric disease has been identified as a possible risk factor for atopic dermatitis development in her children. We quantified the associations between maternal and paternal psychiatric disease and the development of atopic dermatitis in their offspring using nationwide registries.Methods All children in Denmark born between 1 January 1996 and 31 December 2011 who developed atopic dermatitis prior to their fifth birthday were identified and individually matched 1:10 with controls from the general population and with children receiving care in a similar ambulatory/hospital setting. Conditional logistic regression was used to calculate odds ratios (OR) with 95% confidence intervals.Results A total of 8602 children with atopic dermatitis were matched with controls. Rates of parental psychiatric care were similar in the atopic dermatitis and control groups. When compared to the general population, weak associations were found between childhood atopic dermatitis and maternal history of depression [OR 1.18 (95% confidence interval:

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Factors contributing to poor treatment outcomes in childhood atopic dermatitis

Cited by 41 publications

References 71 publications

Topical corticosteroid phobia among caretakers of children with atopic dermatitis: A cross‐sectional study using TOPICOP in Japan

Topical corticosteroid phobia among caretakers of children with atopic dermatitis: A cross‐sectional study using TOPICOP in Japan

Topical Corticosteroid Phobia Among Healthcare Professionals Using the TOPICOP Score

Exploring the association between parental psychiatric disease and childhood atopic dermatitis: a matched case–control study

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