Factors Associated with the Failed Induction of Labour in Post-Term Pregnancy at a Tertiary Care Hospital in Karachi, Pakistan

Makhijani, Pushpa; Kazi, Sarah; Rabia, Syeda

doi:10.36570/jduhs.2017.3.524

Cited by 3 publications

(4 citation statements)

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“…Mothers with fetal weights ≥3.5kg had a 1.2 times higher likelihood of induction failure compared to those with lower fetal weights. This association is consistent with ndings from other studies done in Pakistan (15), Thailand (20), and Tanzania (9). It can be attributed to factors such as poor fetal descent, malposition, and malpresentation in larger babies, hindering optimal application of the fetal head to the cervix and impeding cervical effacement and dilation.…”

Section: Birthsupporting

confidence: 91%

Predictors of failed induction of labor among women delivering at Jinja Regional Referral Hospital: A prospective cohort study

Onanga,

Kasujja,

Ddamulira

et al. 2024

Preprint

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Background:Induction of labor (IOL) is increasingly common in Ugandan referral hospitals but remains a clinical challenge due to its association with adverse maternal and perinatal outcomes. Identifying predictors of failed induction is crucial for optimizing patient care and outcomes. This study aimed to determine the incidence and predictors of failed induction of labor at Jinja Regional Referral Hospital. Materials and Methods: A hospital-based prospective cohort study was conducted among 150 women undergoing labor induction at Jinja Regional Referral Hospital from July 4, 2023, to September 29, 2023. Participants were recruited using a consecutive sampling technique, and data were collected using a pretested questionnaire. A log-binomial regression model was utilized to estimate the relative risk of failed induction for each associated factor, controlling for potential confounders. Results: The incidence of failed induction of labor was 35.33%. Nulliparity (P0) was associated with a heightened risk of failed induction compared to primi/multiparity (P1 or more), as indicated by an adjusted relative risk (aRR) of 1.68 (95% CI: 1.27-2.22, p < 0.001). A pre-induction Bishop score <6 significantly increased the risk, with an aRR of 2.44 (95% CI: 1.63-3.67, p < 0.001). Higher BMI (≥30 kg/m²) was found to pose a substantial risk, with an aRR of 1.87 (95% CI: 1.42-2.48, p < 0.001). Infants with a birth weight ≥3.5kg exhibited a notably elevated risk, with an aRR of 1.14 (95% CI: 1.13-1.14, p < 0.001). Conclusion: The study found a fIOL incidence rate of 35.33%, consistent with the varying global trends, emphasizing the need for standardized definitions and protocols in assessing induction outcomes. Parity, pre-induction Bishop Score, birth weight, and BMI were identified as predictors of fIOL, highlighting the importance of considering maternal characteristics and obstetric factors in predicting induction outcomes.

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Section: Birthsupporting

confidence: 91%

Predictors of failed induction of labor among women delivering at Jinja Regional Referral Hospital: A prospective cohort study

Onanga,

Kasujja,

Ddamulira

et al. 2024

Preprint

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“…Comparative analysis of the studied groups (positive vs. negative blood culture), revealed that gestational age and weight were the same in both groups, with no significant difference regarding sex, place, and mode of delivery between 2 groups. Maternal risk factors were presented in 30.4% of positive blood culture cases with preeclampsia and DM were the predominant risk factor as shown in Fig (1). RDS was the most encountered cause for admission in our cases and also presented in 57% of positive blood culture cases as shown in Fig (2) The relationship between the results of blood culture and lab findings showed that there was no significant difference regarding hemoglobin level and platelets count while there was a significant difference regarding the WBCs Count between both groups.…”

Section: Statisticsmentioning

confidence: 99%

“…Although the major advances in health care of neonatal management, sepsis is still considered as one of the major causes of morbidity and mortality in neonates. It is considered as the commonest cause of neonatal mortality reaching up to 30-50% of the total neonatal deaths each year in developing countries (1) . Timely recognition of sepsis, rational antimicrobial therapy, and aggressive supportive care.…”

Section: Introductionmentioning

confidence: 99%

Microbiological pattern of Neonatal Sepsis in Aswan University Hospital: hospital based study

2021

Aswan University Medical Journal

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Background: Neonatal sepsis is still considered as one of the major causes of morbidity and mortality in neonates. Objective: This study aimed to estimate the prevalence, microbiological pattern, and antibiotic susceptibility of neonatal sepsis in the Neonatal Intensive Care Unit (NICU) in Aswan University Hospital (AUH) in a specific time. Methodology: The study was a prospective cross-sectional study carried out on all neonates admitted to the NICU with suspected neonatal sepsis a from August 2017 to July 2018. All neonates were subjected to history, examination, and investigations which included complete blood count, Creactive protein, and blood cultures at the time of presentation. Results: Our study included 100 neonates with suspected neonatal sepsis. Positive growth in blood culture was 23% of cases. Isolated organisms were 11% S. aureus, 7% K. Pneumonia and 5% Enterobacter cocci. Antibiotic sensitivity revealed that the three organism were sensitive to Ciprofloxacin. All cases were resistant to Erythromycin and Gentamycin. About 8.6% were leucopenic, 38% had leukocytosis and 95.7 % had high CRP. Conclusion: This study revealed increasing rate of neonatal sepsis with high degree of antibiotic resistance to commonly used antibiotics among both gram-positive and gram-negative isolates.

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“…Neonatal sepsis is a recognized cause of morbidity and mortality at this age. In developing countries, sepsis is the commonest cause of neonatal mortality and reported to be responsible for about 50% of the total neonatal deaths annually (2). Sepsis poses a demanding constraint on the heart (3).…”

Section: Introductionmentioning

confidence: 99%

Frequency of Myocardial Dysfunction in Neonatal Sepsis: A Single Center Experience

AboElnour,

AL Gameel,

Hammad

2023

Pediatric Sciences Journal

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Background: Myocardial dysfunction is an association of neonatal sepsis that might occur without underlying cardiac structural defect (CSD). Aims of the work:To study frequency of myocardial dysfunction (MD) in sepsis in full term neonates without CSD. Subjects and Methods: All the full term neonates with neonatal sepsis admitted to Neonatal Intensive Care Unit, Fayoum University between December 2019 and December 2020 without underlying CSD were included in the study. They underwent conventional echocardiography and tissue Doppler studies. Results: 103 neonates with neonatal sepsis were included in the study. Of them 30 patients (29.12%) were found to have myocardial dysfunction. Global myocardial dysfunction was encountered in 16 (53.3%), isolated right ventricle dysfunction in 8 (26.6%) cases, isolated left ventricle dysfunction among 6 (20%). The dysfunction was both systolic and diastolic in 2 (6.6%) cases, isolated systolic in 6 (20%), and isolated diastolic in 22 (73.3 %). No noted risk factors were associated with myocardial dysfunction as age (p=0.193), weight (p=0.100), sex (p=0.130) or type of bacterial infection (p=0.125). The outcome among those with myocardial dysfunction and those without was complete resolution in 13 (43.3%) and 43 (59%) patients (p=0.149), cardiogenic shock and death in 17 cases (56.7%) and 30 (41%) (p=0.149) respectively while no cases developed progressive cardiomyopathy. Conclusions: Full terms with neonatal sepsis can experience significant cardiovascular dysfunction that is either global or limited to right or left ventricle. The dysfunction might be systolic or diastolic or both. Myocardial dysfunction among neonates with sepsis might be selflimiting or culminates increasing the risk of mortality.

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Factors Associated with the Failed Induction of Labour in Post-Term Pregnancy at a Tertiary Care Hospital in Karachi, Pakistan

Cited by 3 publications

References 0 publications

Predictors of failed induction of labor among women delivering at Jinja Regional Referral Hospital: A prospective cohort study

Predictors of failed induction of labor among women delivering at Jinja Regional Referral Hospital: A prospective cohort study

Microbiological pattern of Neonatal Sepsis in Aswan University Hospital: hospital based study

Frequency of Myocardial Dysfunction in Neonatal Sepsis: A Single Center Experience

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