Objective:To determine the prevalence, etiology and complications of emergency obstetric hysterectomy (EOH) at a tertiary care hospital in Karachi.Methods:This was a retrospective cohort study which was carried out in the Department of Obstetrics & Gynecology Unit II, Civil Hospital Karachi from March 2015 to March 2017. All patients undergoing EOH were included in the study. Data was collected from medical files and labor room registers in accordance with ethical guidelines. Information included demographic characteristics, reasons for EOH, procedure associated morbidity and mortality. Data was recorded on a predesigned pro forma and analyzed using IBM SPSS Statistics for Macintosh, Version 18.0.Results:Out of 7,968 deliveries in two years, 32 patients under went EOH, (prevalence 4.01 per 1,000 deliveries). The mean age was 30.0 ± 5.2 years. Most women (75%) were multipara. The main mode of delivery was caesarean section (80%), mostly done as an emergency procedure (81%). In 10(30%) patients EOH was performed for uncontrollable hemorrhage due to uterine atony, followed by a morbidly adherent placenta (28%). Morbidity included disseminated intravascular coagulation (DIC) in four patients(19%) and three patients underwent repeat laparotomy for uncontrollable hemorrhage. There were three maternal deaths, giving a case-fatality index of 9.3%.Conclusion:Uterine atony and morbidly adherent placenta were the main reasons for emergency obstetric hysterectomy (EOH) in our set up.

To compare the effect of abdominal binder versus no binder after major abdominal surgery and cesarean section on various post-operative recovery parameters.

IntroductionThe ABO blood group type has been considered an independent risk factor in the occurrence of pregnancyrelated complications leading to significant morbidity and mortality in pregnant mothers and neonates. This study aims to determine the maternal ABO blood group and its correlation with pregnancy-related complications. MethodsWe analysed data of 497 pregnant female patients aged between 25 and 40 years who presented with a gestational age of > 14 weeks from June 1, 2020, to November 30, 2020. Patients' age, parity, gestational age at the first visit, body mass index (BMI) at the first visit, ABO blood group, gestational age at delivery, mode of delivery, birth weight of neonate, and pregnancy-related complications including preeclampsia, gestational diabetes mellitus (GDM), preterm delivery, low birth weight (LBW), and small for gestational age (SGA) infants were evaluated. ResultsThe mean age of 497 patients was 27.6 (27.62 ± 3.35) years. Mean BMI was 22.7 (22.7 ± 3.1 kg/m 2 ), parity was 1.85 (1.85 ± 2.3), gestational age at first visit was 23.19 (23.19 ± 3.4) weeks and gestational age at delivery was 37.0 (37.0 ± 2.6) weeks. There were 205 (41.25%) spontaneous vaginal delivery and 292 (58.75%) cesarean sections. The average birth weight of the neonate was 2684.31 ± 622.4 g. Preeclampsia was observed in 107 (21.53%), GDM in 17 (3.42%), and preterm delivery in 154 (30.99%) women. Considering the neonatal outcome, 124 (24.95%) babies had LBW and 49 (9.86%) were SGA. The rate of preeclampsia and GDM was not statistically significant among different blood groups while the rate of preterm delivery, LBW, and SGA was significant among women with different blood groups. ConclusionWe conclude that the ABO blood group is associated with maternal and neonatal pregnancy-related complications when considering the risk of preterm delivery, LBW, and SGA but not with GDM and preeclampsia. This finding will help clinicians to identify the patients at risk of developing pregnancyrelated complications and hence, to take timely and appropriate measures.

In this paper we have used sentiment analysis on news articles to see its effect on stock prices. We collected our dataset using Bing API which gave us links to news articles about a specific company. As no pre-existing sentiment dictionary specifically for stock articles exited, we created a specialized sentiment dictionary only meant to analyze stock articles. Two different machine learning algorithms were applied to the dataset and the accuracy of the two was compared. In order to test our results we attached an overall sentiment to each article in our data set which was compared to the predicted sentiment by the algorithm. We also compared the predicted results with the actual change in the stock prices on the market.

IntroductionInduction of labor (IOL) is characterized by stimulating contractions of the uterus just before the instantaneous onset of labor, with or without amniotomy. According to the recommendation of the World Health Organization (WHO), induction must only be carried out when there is a clear medical need for one and when potential benefits outweigh the expected harm that may be caused by it. The present study was to determine the frequency of fetomaternal outcomes among pregnant women subject to the induction of labor. MethodsThe present prospective cross-sectional study was conducted over a period of one year starting from June 17, 2018, to July 25, 2019, in the Department of Obstetrics and Gynecology Unit III, Civil Hospital Karachi. After institutional ethical committee approval, 302 pregnant women who were subject to induction of labor were enrolled using a non-probability consecutive sampling technique. Outcome variables, i.e., postpartum hemorrhage, mode of delivery, hospital stay more than seven days, birth asphyxia, Apgar score < 7 at five minutes, neonatal jaundice, and low birth weight were noted. IBM Statistical Package for Social Sciences (SPSS) Statistics for Windows, version 21.0 (IBM Corp., Armonk, NY) was used for data analysis. ResultsA total of 302 women with an average age range was 18-45 years with a mean age of 28.5 ± 4.47, body mass index (BMI) 29.83 ± 3.83, and mean gestational age was 37 ± 4.3. Almost 205 (67.9%) of the cases were booked. One hundred and eighty (59.6%) were nulliparas, 57(18.8%) had para-1, 43 (14.4%) had para-2, and 22 (7.14%) had par-3. When fetomaternal outcome among the pregnant women subject to induction of labor was observed, postpartum hemorrhage was observed in 55 (18.21%), hospital stay more than seven days was in 51 (17%), birth asphyxia was in 45 (14.9%), neonatal jaundice was in 53 (17.6%), low birth weight was in 15 (4.96%), Apgar score < 7 was in 48 (16%), 39 (13%) women underwent for C-section and 263 (87%) of the women delivered vaginally. ConclusionThis study concludes that the induction of labor (IOL) is safe and reliable and less risk of adverse fetomaternal outcome is associated with pregnancies between 37 weeks and 42 weeks of gestation. The evidence regarding IOL prior to 37 weeks and beyond 42 weeks of gestation is inadequate to reach any conclusion.