2018
DOI: 10.1093/occmed/kqy051
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Factors associated with positive Mantoux results in NHS healthcare workers

Abstract: BCG vaccination, stay or work in a high TB prevalence country and previous TST were associated with positive Mantoux results. These factors could be used to predict Mantoux results, with the potential of substituting Mantoux testing.

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“…Providing a definitive diagnostic test such as the IGRA testing to HCW with positive TST could enhance treatment uptake. Some HCWs felt that TST was not diagnostic and there is a possibility of false positive results due to multiple factors such as the misconception of history of BCG vaccination and working in an environment with continuous exposure to active TB [ 35 ]. In TST-positive patients, studies had supported the use of IGRA to reduce false positive results of TST and improve clinical management of LTBI [ 36 , 37 ].…”
Section: Discussionmentioning
confidence: 99%
“…Providing a definitive diagnostic test such as the IGRA testing to HCW with positive TST could enhance treatment uptake. Some HCWs felt that TST was not diagnostic and there is a possibility of false positive results due to multiple factors such as the misconception of history of BCG vaccination and working in an environment with continuous exposure to active TB [ 35 ]. In TST-positive patients, studies had supported the use of IGRA to reduce false positive results of TST and improve clinical management of LTBI [ 36 , 37 ].…”
Section: Discussionmentioning
confidence: 99%