Factors associated with mortality after an asthma admission: A national United Kingdom database analysis

Abstract

Co-morbid conditions experienced by older asthma patients may contribute to mortality post an asthma admission and greater understanding of risk factors contributing to fatality are required.

Fatores associados à mortalidade em pacientes hospitalizados por asma aguda grave em 1994, 1999 e 2004 na Espanha e América Latina

“…The mortality rate among patients hospitalized in Spain and Latin America was similar to that found in previous studies conducted in the United States and the United Kingdom (less than 1% of all admissions). (12)(13) Most of the patients who died were over 34 years of age. In addition, recent studies have reported that the incidence of asthma-related in-hospital mortality is higher among women than among men.…”

“…In addition, recent studies have reported that the incidence of asthma-related in-hospital mortality is higher among women than among men. (13)(14)18) Although it is difficult to understand why the mortality risk is greater for female patients hospitalized for asthma, it might be due to the gender bias (predominance of females) among adults with asthma. Among patients with severe asthma, the female/male ratio can be as high as 4:1.…”

“…Among patients with severe asthma, the female/male ratio can be as high as 4:1. (13)(14)19) In addition, biological differences and other factors, including environmental concerns, poverty, and quality of care, might play a role. (20) Finally, 72% of the deaths appeared to be attributable to out of hospital cardiopulmonary arrest and the resulting anoxic encephalopathy.…”

“…However, there have been few studies assessing the characteristics of patients with acute asthma who died during hospitalization, and most have been conducted in countries such as the United States or those in the United Kingdom. (12)(13) Very few studies have reported data from Latin America or Spain. (14) In order to address this lack of information, we conducted a multinational, multicenter retrospective study to evaluate, for the first time, the characteristics of patients with acute asthma who died during hospitalization in Spain and Latin America, as well as to evaluate factors associated with asthma mortality.…”

A Pharmaco-Economic Analyzis of Treating Severe Uncontrolled Child Asthma with Omalizumab — Actual Russian Clinical Practice Data

“…Статистика смертности больных БА в РФ неизвестна, поэтому при моделировании была использована экстра-поляция риска смерти по сравнению с обычной популя-цией у больных БА в Великобритании на основе открытых данных [26]. Средневзвешенный по возрастным группам риск смерти для больных БА вне обострения по отноше-нию к обычной популяции в Великобритании составил 0,8 (что интерпретировалось нами как отсутствие разли-чий), а во время астматического статуса риск смерти был повышен в 5,7 раз.…”