Factors Associated With Influenza in an Emergency Department Setting

Pedersen, Courtney J.; Quinn, James V.; Rogan, Daniel T.; Yang, Samuel

doi:10.1016/j.jemermed.2018.12.012

Cited by 12 publications

(17 citation statements)

References 21 publications

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“…On the other hand, sore throat, conjunctival hyperemia, tearing, sneezing, sputum production, dyspnea, vomiting and rhonchi at pulmonary auscultation were more frequently described in influenza group than COVID-19 group with statistically significant differences. Sore throat was a well-known symptom in influenza, found in about 30e40% of the patients in the literature as in our study [25,27,28]. Conjunctival hyperemia seems to be rare with COVID-19, less than 5% of cases in our study vs 30% of cases in influenza group (p < 0.001).…”

Section: Comparison Of Patients With Covid-19 and Patients With Influsupporting

confidence: 50%

“…On the contrary, in a cohort from an emergency department including 119 patients with confirmed influenza no one had diarrhea. Pedersen et al conclude that the absence of gastrointestinal symptoms was one of the factors that can help distinguish influenza from other acute respiratory illnesses in the ambulatory population [25]. During pulmonary auscultation, cracklings sounds were statistically more frequents in COVID-19 group than influenza group (39% vs 20%, p ¼ 0,032), especially bilateral cracklings (24% vs 9%, p ¼ 0.034).…”

Section: Comparison Of Patients With Covid-19 and Patients With Influmentioning

confidence: 99%

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Clinical features of COVID-19 and influenza: a comparative study on Nord Franche-Comte cluster

Zayet

Kadiane-Oussou

Lepiller

et al. 2020

Microbes and Infection

176

175

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Clinical descriptions about influenza-like illnesses (ILI) in COVID-19 seem non-specific. We aimed to compare the clinical features of COVID-19 and influenza. We retrospectively investigated the clinical features and outcomes of confirmed cases of COVID-19 and influenza in Nord Franche-Comt e Hospital between February 26th and March 14th 2020. We used SARS-CoV-2 RT-PCR and influenza virus A/B RT-PCR in respiratory samples to confirm the diagnosis. We included 124 patients. The mean age was 59 (±19 [19e98]) years with 69% female. 70 patients with COVID-19 and 54 patients with influenza A/B. Regarding age, sex and comorbidities, no differences were found between the two groups except a lower Charlson index in COVID-19 group (2 [±2.5] vs 3 [±2.4],p ¼ 0.003). Anosmia (53% vs 17%,p < 0.001), dysgeusia (49% vs 20%,p ¼ 0.001), diarrhea (40% vs 20%,p ¼ 0.021), frontal headache (26% vs 9%,p ¼ 0.021) and bilateral cracklings sounds (24% vs 9%,p ¼ 0.034) were statistically more frequent in COVID-19. Sputum production (52% vs 29%,p ¼ 0.010), dyspnea (59% vs 34%,p ¼ 0.007), sore throat (44% vs 20%,p ¼ 0.006), conjunctival hyperhemia (30% vs 4%,p < 0.001), tearing (24% vs 6%,p ¼ 0.004), vomiting (22% vs 3%,p ¼ 0.001) and rhonchi sounds (17% vs 1%,p ¼ 0.002) were more frequent with influenza infection. We described several clinical differences which can help the clinicians during the cocirculation of influenza and SARS-CoV-2.

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Section: Comparison Of Patients With Covid-19 and Patients With Influsupporting

confidence: 50%

Section: Comparison Of Patients With Covid-19 and Patients With Influmentioning

confidence: 99%

Clinical features of COVID-19 and influenza: a comparative study on Nord Franche-Comte cluster

Zayet

Kadiane-Oussou

Lepiller

et al. 2020

Microbes and Infection

176

175

View full text Add to dashboard Cite

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“…Both groups presented with gastrointestinal symptoms such as diarrhea and vomiting in our study. Several studies suggest that the presence of gastrointestinal symptoms such as diarrhea in adult COVID-19 patients is an important subjective finding that distinguishes it from other viral illnesses [10,11]. İnfluenza infection is characterized by fever and respiratory tract symptoms in all age groups, however, gastrointestinal symptoms such as diarrhea, and vomiting are often observed among young children [12].…”

Section: Discussionmentioning

confidence: 99%

Comparison of clinical features and laboratory findings of coronavirus disease 2019 and influenza A and B infections in children: a single-center study

Siddiqui

Gultekingil²,

Bakırcı³

et al. 2021

Clin Exp Pediatr

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“…In other studies, influenza patients with complaints longer than 3 or 7 days were excluded. 1,13,14 Neuraminidase inhibitors may alleviate the course of the disease, particularly if administered within 48 hours of onset. We started treatment directly in our emergency department in 81% of patients.…”

Section: Discussionmentioning

confidence: 99%

Clinical Characteristics of Influenza in Season 2017/2018 in a German Emergency Department: A Retrospective Analysis

et al. 2019

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Introduction: Influenza infection is a viral disease with significant morbidity and mortality during the cold months. Clinical presentation typically includes cough, fever, and pain. Influenza disease is hardly diagnosed only on the basis of clinical symptoms due to similar clinical presentation of other diseases such as a typical cold or other flu-like diseases. We evaluated patients with proven influenza who presented at an emergency department of internal medicine in a university hospital according to the clinical presentation and different age groups. Materials and Methods: From October 2017 to April 2018, 723 reverse transcription-polymerase chain reaction (RT-PCR) tests for influenza were performed in the emergency department on patients with suspected influenza diagnosed clinically. A total of 240 influenza-positive patients were retrospectively assessed for documented main symptoms, vital parameters, risk factors for an unfavorable course, hospitalization, and death. Results: The mean age of influenza patients was 65 years. Overall, 30 patients were aged 18 to 39 years, 48 patients 40 to 59 years, and 162 patients ⩾60 years. Influenza B in 168 (70%) was predominant to 72 influenza A (mostly H1N1). In only 30% of the patients all three typical symptoms (cough, fever, and headache/myalgia) were documented. Headache or myalgia (with 34%) was rather uncommon in influenza B. Sudden onset was cited in only 5.4%; 57% of all influenza patients were in hospital for a mean of 7.1 days, and 5.8% of all influenza patients died. Patients aged above 60 years had more risk factors, showed typical symptoms less frequently, and were hospitalized longer than younger patients (<60 and <40 years). Conclusions: At an emergency department of internal medicine, influenza-diseased patients are of higher age, show an increased number of comorbidities, and are more likely to have milder symptoms documented. Elderly patients with influenza have a higher hospitalization rate with a longer hospital stay as compared with younger patients.

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Factors Associated With Influenza in an Emergency Department Setting

Cited by 12 publications

References 21 publications

Clinical features of COVID-19 and influenza: a comparative study on Nord Franche-Comte cluster

Clinical features of COVID-19 and influenza: a comparative study on Nord Franche-Comte cluster

Comparison of clinical features and laboratory findings of coronavirus disease 2019 and influenza A and B infections in children: a single-center study

Clinical Characteristics of Influenza in Season 2017/2018 in a German Emergency Department: A Retrospective Analysis

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