Factors Associated With Anthropometric Indicators of Nutritional Status in Children With Chronic Kidney Disease Undergoing Peritoneal Dialysis, Hemodialysis, and After Kidney Transplant

Verduzco, Julieta García De Alba; López, Erika Fabiola Hurtado; Vázquez, C; Serrano, Adriana de la Torre; Romero‐Velarde, Enrique; Garibay, Edgar M Vásquez

doi:10.1053/j.jrn.2018.03.002

Cited by 7 publications

(3 citation statements)

References 24 publications

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“…[ 6 ] In 33 European children on dialysis,[ 4 ] reduced fat stores was observed in 24% using BIA-BF% and similar findings were noted in other studies using BIA and skin fold thickness. [ 6 7 ] We observed preserved body fat in majority of children by both DXA and BIA despite a high prevalence of low MUAC. This finding suggests that muscle wasting is profound in these children resulting in low MUAC.…”

Section: Discussionmentioning

confidence: 78%

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Body fat in children with chronic kidney disease - A comparative study of bio-impedance analysis with dual energy X-ray absorptiometry

et al. 2021

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Introduction: Nutritional impairment in patients with chronic kidney disease (CKD) is due to decreased body stores of both protein and fat. We need a tool that can be used in clinics to determine and monitor fat composition with a special focus on normalizing fat measurements to height in these children. Bio-impedance analysis (BIA), a portable and simple tool, has been used to estimate body fat in children with CKD but needs validation against the reference tool dual energy X-ray absorptiometry (DXA). The purpose of the cross-sectional study was to estimate the prevalence of low body fat in children with stages 2-5 CKD (non-dialysis) and CKD 5D (dialysis), and to compare fat measures from two different methods namely BIA and DXA. Method: Children in stages 2–5 CKD ( n = 19) and in CKD 5D ( n = 14) were recruited for assessment of fat mass (FM, Kg) by BIA and DXA, from which percent body fat (BF %) and fat mass index (FMI, Kg/M 2 ) were obtained. Low body fat was defined as <5 th age and gender centile for BF% or FMI by DXA and BF% by BIA. Results: Low body fat was detected equally using BF% and FMI in 18% of children by DXA while only 12% were detected using BF% by BIA. In children with CKD2–5, a good degree of reliability was found with FMI measurements (ICC 0.76 CI [0.48,0.9]) and poor reliability in children with CKD 5D (ICC 0.58 CI [0.1,0.84]). BF% had poor to fair reliability in the children with CKD 2-5 and CKD 5D (ICC 0.64 [0.28,0.84] and 0.53 [0.02,0.82]), respectively. Comparing BF% and FMI obtained by BIA and DEXA, BIA overestimated BF% by 3.5% in comparison to DXA. Conclusion: In children with CKD, body fat is preserved in the majority. Among the two measures of fat, BF% estimated by BIA did not compare well with DXA while FMI measure was comparable with a lower bias. However, due to lack of reference values in Indian children for FMI obtained by BIA, BIA cannot be used to measure fat in this population.

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Section: Discussionmentioning

confidence: 78%

“…[ 3 ] While few studies[ 4 5 ] have observed body fat to be preserved in majority of children with CKD, others have shown fat deficits in these children. [ 6 7 ].…”

Section: Introductionmentioning

confidence: 99%

Body fat in children with chronic kidney disease - A comparative study of bio-impedance analysis with dual energy X-ray absorptiometry

et al. 2021

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“… 105 A global survey of 160 countries identified that patient out-of-pocket costs for KRT are greatest in low-income countries and lower-middle income countries, with patients bearing 100% of transplantation costs in 20% of low-income countries. 116 Burdens appear to be particularly extreme for HD, 105 , 117 with transport costs estimated to be 5.5 times as expensive for families with a child on HD compared to peritoneal dialysis in South Africa (∼27% of monthly income for those on HD). 118 High transport costs have also been reported for families receiving free HD in Pakistan.…”

Section: Aimsmentioning

confidence: 99%