Mobile commerce (m‐commerce) is extensively being deployed in both formal and informal sectors in Africa. There is evidence that mobile services such as m‐commerce can improve the overall revenue and productivity in various sectors globally. M‐commerce interventions have gained popularity for the last decades owing to their nature of being ubiquitous, convenient, localised, and personalised. However, there is little comprehensive and integrated literature on m‐commerce services on the informal sector in the developing countries in Africa. This article therefore provides results of systematic review from literature on the opportunities, barriers, and adoption factors of m‐commerce services for the informal sector in Africa. This systematic review followed the Preferred Reporting Items for System Reviews and Meta‐Analysis (PRISMA) guidelines. Out of 459 records that were screened, 20 was the final number of eligible studies after applying the exclusion criteria. This systematic review found that there are technical, social, cultural, and financial factors that hamper the uptake of m‐commerce for the informal sector in Africa. Furthermore, benefits and m‐commerce adoption factors have also been discussed. The study finally provides recommendations for the effective and sustainable utilisation of m‐commerce services for the informal sector in Africa.