A recent trend in the development of CO2 pipelines is the shift from the predominance of transport of CO2 for enhanced oil recovery (EOR) to the transportation of CO2 as part of the carbon capture and storage (CSS) process for global warming mitigation. Among the processes of capture, transport, and storage, less attention has been paid to transport as it is assumed to be for granted, existing technology. This paper presents a focused analysis of the problem of structural integrity of CO2 pipelines through reviewing the state-of-the-art literature and practice, and highlights the need for a unified code of practice for the modelling of integrity and, due to the potentially hazardous nature of CO2, safety, in these pipelines.